DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG31100 and ATR1

DIOPT Version :9

Sequence 1:NP_001262395.1 Gene:CG31100 / 41075 FlyBaseID:FBgn0051100 Length:716 Species:Drosophila melanogaster
Sequence 2:NP_013591.1 Gene:ATR1 / 854924 SGDID:S000004584 Length:542 Species:Saccharomyces cerevisiae


Alignment Length:528 Identity:103/528 - (19%)
Similarity:182/528 - (34%) Gaps:174/528 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   267 FNQLYDELITQ-------KAIELSADGIPPPGQRRTLGQRLRMWRKRSFLVPFLLVSFSFFTGHF 324
            |..:..:|:.|       ..:.:.:|.....|..::       |...||  |.:..||...:|..
Yeast    73 FTCMISQLLNQAGTTQTLSIMNILSDSFGSEGNSKS-------WLMASF--PLVSGSFILISGRL 128

  Fly   325 SG-----KTPLQTYAVQIFHTLKAPMNKYHAT----IL------LGVAEMLATILGVVLIHFTGK 374
            ..     |..|..|.:.|..:|...:.||..:    |:      ||:|.:|..:||::...:.|.
Yeast   129 GDIYGLKKMLLVGYVLVIIWSLICGITKYSGSDTFFIISRAFQGLGIAFVLPNVLGIIGNIYVGG 193

  Fly   375 --RPLVLVSTVG-------TGLCFF----GT--------ATYAHFLSEVPGFTVNNVVVNAS--- 415
              |..:::|.||       |..|.|    ||        |.||:.::....|.::...:.::   
Yeast   194 TFRKNIVISFVGAMAPIGATLGCLFAGLIGTEDPKQWPWAFYAYSIAAFINFVLSIYAIPSTIPT 258

  Fly   416 -----------SIMPKEGILSQQNISKIFETEQQAIRQETERFTTQLPDIETTTLFDQEIYNRSR 469
                       |::...|::...     |...|..|....:.:...:..|....|....||.   
Yeast   259 NIHHFSMDWIGSVLGVIGLILLN-----FVWNQAPISGWNQAYIIVILIISVIFLVVFIIYE--- 315

  Fly   470 RDVVEMMTTDAPMDTTMWPEPSSSPEPIASSSLAPPSTSVKPPLVEELLLVVPKQEHNYLVWVPL 534
                                                ....|.||:...::   |..|       :
Yeast   316 ------------------------------------IRFAKTPLLPRAVI---KDRH-------M 334

  Fly   535 ILLLLSAFFSHLGIRMLPWILIGEV------FPAEIRNSASGFAGGVGYIF---GFLANKLFLLM 590
            |.::|:.||.        |...|..      |...||...:.:|||..::|   |.:|     .:
Yeast   335 IQIMLALFFG--------WGSFGIFTFYYFQFQLNIRQYTALWAGGTYFMFLIWGIIA-----AL 386

  Fly   591 LSALTL----PGTFAFYASVAF-FGTVVLYFT-LPETEGRT-LGE-------IEAHFSKKSDVNL 641
            |...|:    |..|.|::.||| .|:::...| :.||..|| ||.       ::..|...|.:. 
Yeast   387 LVGFTIKNVSPSVFLFFSMVAFNVGSIMASVTPVHETYFRTQLGTMIILSFGMDLSFPASSIIF- 450

  Fly   642 LRKQPSNKLPIKDEAQFPGNTINMQGNFQVPIT----STQQTKIIHLQQSDFTPRSQNGRTA--- 699
                 |:.||::.:. ..|:.:|...|:.:.:.    :|.:|::    .||.....:..|.|   
Yeast   451 -----SDNLPMEYQG-MAGSLVNTVVNYSMSLCLGMGATVETQV----NSDGKHLLKGYRGAQYL 505

  Fly   700 GVGLSNPA 707
            |:||::.|
Yeast   506 GIGLASLA 513

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31100NP_001262395.1 MFS 59..>232 CDD:119392
Sugar_tr 98..633 CDD:278511 85/445 (19%)
MFS <531..616 CDD:119392 24/98 (24%)
ATR1NP_013591.1 MFS_Amf1_MDR_like 73..517 CDD:341029 103/528 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0254
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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