DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31100 and AMF1

DIOPT Version :9

Sequence 1:	NP_001262395.1	Gene:	CG31100 / 41075	FlyBaseID:	FBgn0051100	Length:	716	Species:	Drosophila melanogaster
Sequence 2:	NP_015023.1	Gene:	AMF1 / 854560	SGDID:	S000005905	Length:	515	Species:	Saccharomyces cerevisiae

Alignment Length:	401	Identity:	77/401 - (19%)
Similarity:	130/401 - (32%)	Gaps:	124/401 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 QGGEGRSETSGDIL------LNKDEISWFSSINLICVPLGCLFSGLLTQPLGKRRAMQFVNLPIL 137
            |.|.|:|.....|:      .|..::|||:|...:.|....|.:|.|....|.::   |..|...
Yeast    57 QAGLGQSLAPLHIIGNSFGTTNAGQLSWFASAYSLTVGTFILIAGRLGDIFGHKK---FFVLGFF 118

  Fly   138 --AAW-LMFHFATRTEHLYAALCLA--GLGGGLMEAPVLTYVAEITEPKYRG--ILSALGTTC-- 193
              |.| |:..|:..:..::...|.|  |:|...:....:..:....:|..|.  :.|..|.:.
Yeast   119 WYALWSLLAGFSVYSNQIFFDCCRAFQGMGPAFLLPNAIAILGRTYKPGRRKNMVFSLFGASAPG 183

  Fly   194 -VITGVFIQFILGSLMDWRSVAAVSSAFPVITIIMLCFV---------PESPVWLIREQRFREAV 248
             ...|.....:||.|..|      ..|:.::.|  .|||         |.:|:    ..|...:.
Yeast   184 GFFLGAVFSSMLGQLAWW------PWAYWIMGI--ACFVLAVAGYFVIPHTPM----PSRDASSF 236

  Fly   249 KSLQWLRGWVPEHMIEAEFNQLYDELITQKAIELSADGIPPPGQRRTLGQRLRMWRKRSFLVPFL 313
            |.|                                              :|:......:.:|..:
Yeast   237 KLL----------------------------------------------ERIDFAGSVTGVVGLI 255

  Fly   314 LVSFSFFTGHFSG-KTPLQTYAVQI----FHTLKAPMNKYHATILLGVAEM---LATILGVVL-- 368
            |.:|::..|...| :|| .|||:.|    |..:.|.:....|..||..|.:   .|.:|..:.
Yeast   256 LFNFAWNQGPVVGWQTP-YTYALLIVGTFFLVIFAYIESRAAFPLLPFAALSSDTAFVLSCIAAG 319

  Fly   369 -------IHFT--------GKRPLV------------LVSTVGTGLCFFGTATYAHFLSEVPGFT 406
                   |.:|        |:.||:            ..:.|.||.....|......|..:..||
Yeast   320 WASFGIWIFYTWQFMEDSRGQTPLLSSAQFSPVAISGFCAAVTTGFLLSHTPPSTVMLFAMTAFT 384

  Fly   407 VNNVVVNASSI 417
            |..:::..:.:
Yeast   385 VGTILIATAPV 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31100	NP_001262395.1	MFS	59..>232	CDD:119392	39/177 (22%)
		Sugar_tr	98..633	CDD:278511	71/376 (19%)
		MFS	<531..616	CDD:119392
AMF1	NP_015023.1	MFS_Amf1_MDR_like	48..493	CDD:341029	77/401 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900