Protein Alignment CG31100 and Slc2a8

DIOPT Version :9

• Sequence 1: NP_001262395.1
• Gene: CG31100 / 41075
• FlyBaseID: FBgn0051100
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_445946.2
• Gene: Slc2a8 / 85256
• RGDID: 620611
• Length: 478
• Species: Rattus norvegicus
• Alignment Length: 594
• Identity: 129/594 - (21%)
• Similarity: 227/594 - (38%)
• Gaps: 156/594 - (26%)

  Fly    51 FLAVSIKNILLFGYGMTLGFPTIVIPAIQGGEGRSETSGDILLNKDEISWFSSINLICVPLGCLF 115
            |||.....:....:|..||:.:..||::     |......:.|.....|||.::..:....|.:.
  Rat    27 FLATFAAALGPLSFGFALGYSSPAIPSL-----RRTAPPALRLGDTAASWFGAVVTLGAAAGGVL 86

  Fly   116 SGLLTQPLGKRRAMQFVNLPILAAWLMFHFATRTEHLYAALCLAGLGGGL--MEAPVLTYVAEIT 178
            .|.|....|::.::....:|.:..:.:...|.....|.....|.||..|:  :.|||  |::||.
  Rat    87 GGWLLDRAGRKLSLLLCTVPFVTGFAVITAARDVWMLLGGRLLTGLACGVASLVAPV--YISEIA 149

  Fly   179 EPKYRGILSALGTTCVITGVFIQFILGSLMDWRSVAAVSSAFPVITIIMLCFVPESPVWLIREQR 243
            .|..||:|.:.....|:||:.:.::.|.:::||.:|.:....|.:.::::|::||:|.:|:.:.:
  Rat   150 YPAVRGLLGSCVQLMVVTGILLAYVAGWVLEWRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQ 214

  Fly   244 FREAVKSLQWL----RGWVPEHMIEAEFNQLYDELITQKAIELSADGIPPPGQRRTLGQRLRMWR 304
            ::||:.:|::|    .||              :|              ||.|.... |.:|.|.|
  Rat   215 YQEAMAALRFLWGSEEGW--------------EE--------------PPVGAEHQ-GFQLAMLR 250

  Fly   305 KRSFLVPFLLVSFSFFTGHFSGKTPLQTYAVQIFHTLKAPMNKYHATILLGVAEMLATILGVVLI 369
            :.....|.::..........||...:..||..||...|...:.. |::.:|:.::|.|.:..:::
  Rat   251 RPGVHKPLIIGICLMVFQQLSGVNAIMFYANTIFEEAKFKDSSL-ASVTVGIIQVLFTAVAALIM 314

  Fly   370 HFTGKRPLVLVSTVGTGLCFFGTATYAHFLSEVPGFTVNNVVVNASSIMPKEGILSQQNISKIFE 434
            ...|::.|:.:|.|                                 ||    :.|.......|:
  Rat   315 DRAGRKLLLALSGV---------------------------------IM----VFSMSAFGTYFK 342

  Fly   435 TEQQAIRQETERFTTQLPDIETTTLFDQEIYNRSRRDVVEMMTTDAPMDTTMWPEPSSSPEPIAS 499
            ..|..                                                  ||:|..
  Rat   343 LTQSG--------------------------------------------------PSNSSH---- 353

  Fly   500 SSLAPPSTSVKPPLVEELLLVVPKQEHNYLVWVPL--ILLLLSAFFSHLGIRMLPWILIGEVFPA 562
                   ..:..|:..|     |...|..|.|:.:  :.|.::.|  .:|...:||:|:.|:||.
  Rat   354 -------VGLLVPISAE-----PADVHLGLAWLAVGSMCLFIAGF--AVGWGPIPWLLMSEIFPL 404

  Fly   563 EIRNSASGFAGGVGYIFGFLANKLFLLMLSALTLPGTFAFYASVAFFGTVVLYFTL---PETEGR 624
            .|:..|:|......:...||..|.|..::..|...|  ||:.:.||....|| |||   |||:||
  Rat   405 HIKGVATGVCVLTNWFMAFLVTKEFNSIMEILRPYG--AFWLTAAFCILSVL-FTLTFVPETKGR 466

  Fly   625 TLGEIEAHF 633
            ||.:|.|||
  Rat   467 TLEQITAHF 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31100	NP_001262395.1	MFS	59..>232	CDD:119392	40/174 (23%)
		Sugar_tr	98..633	CDD:278511	117/545 (21%)
		MFS	<531..616	CDD:119392	25/86 (29%)
Slc2a8	NP_445946.2	Dileucine internalization motif. /evidence=ECO:0000269|PubMed:10671487	12..13
		MFS	27..470	CDD:421695	125/587 (21%)
		Monosaccharide binding. /evidence=ECO:0000250|UniProtKB:P11166	268..274		2/5 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920