DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31100 and TMT2

DIOPT Version :9

Sequence 1:	NP_001262395.1	Gene:	CG31100 / 41075	FlyBaseID:	FBgn0051100	Length:	716	Species:	Drosophila melanogaster
Sequence 2:	NP_001190923.1	Gene:	TMT2 / 829684	AraportID:	AT4G35300	Length:	739	Species:	Arabidopsis thaliana

Alignment Length:	760	Identity:	155/760 - (20%)
Similarity:	256/760 - (33%)	Gaps:	229/760 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 GFPTIVIPAIQG----GEGRSETSGDILLNKDEISWFS---------SINLICVPLGCLFSGLLT 120
            |...:.|.|..|    |...:..:|.:|..|.|.:..|         :::||...|....||.:.
plant     3 GAVLVAIAAAVGNLLQGWDNATIAGAVLYIKKEFNLESNPSVEGLIVAMSLIGATLITTCSGGVA 67

  Fly   121 QPLGKRRAMQFVNLPILAAWLMFHFATRTEHLYAALCLAGLGGGLMEAPVLTYVAEITEPKYRGI 185
            ..||:|..:...::......|:..::.....|.....|.|.|.||:...|..|::|...|:.||:
plant    68 DWLGRRPMLILSSILYFVGSLVMLWSPNVYVLLLGRLLDGFGVGLVVTLVPIYISETAPPEIRGL 132

  Fly   186 LSALGTTCVITGVFIQF--ILG-SLM---DWRSVAAV----SSAFPVITIIMLCFVPESPVWLIR 240
            |:.|.......|:|:.:  :.| |||   .||.:..|    |..|..:|:.   |:||||.||:.
plant   133 LNTLPQFTGSGGMFLSYCMVFGMSLMPSPSWRLMLGVLFIPSLVFFFLTVF---FLPESPRWLVS 194

  Fly   241 EQRFREAVKSLQWLRG---------------------WVPEHMIEAEFNQLYDELITQKAIELSA 284
            :.|..||.:.||.|||                     .:.|::|...     ||:.....|.:..
plant   195 KGRMLEAKRVLQRLRGREDVSGEMALLVEGLGIGGETTIEEYIIGPA-----DEVTDDHDIAVDK 254

  Fly   285 DGIPPPGQRRTLGQRLR-----------------MWRKRSFLVPFLLVSFSFF------TG---- 322
            |.|...|....|....|                 |.|::..|:..|:..|...      ||
plant   255 DQIKLYGAEEGLSWVARPVKGGSTMSVLSRHGSTMSRRQGSLIDPLVTLFGSVHEKMPDTGSMRS 319

  Fly   323 ----HFSG--------------------------------------KTPL---QTYAVQ--IFHT 340
                ||..                                      .:||   ||.:::  :.||
plant   320 ALFPHFGSMFSVGGNQPRHEDWDEENLVGEGEDYPSDHGDDSEDDLHSPLISRQTTSMEKDMPHT 384

  Fly   341 LKAPMNKY-HATILLGVAEMLATILGV--------------------------VLIH---FTGKR 375
            ....::.: |.:.:.|.....|..:|:                          :.:|   |.|.|
plant   385 AHGTLSTFRHGSQVQGAQGEGAGSMGIGGGWQVAWKWTEREDESGQKEGGFKRIYLHQEGFPGSR 449

  Fly   376 PLVLVSTV---GTGLCFFGTATYAHFLSEVPGFTVNNVVVNASSIMPKEGILSQQNISKIF---- 433
            ...:||..   |||...|..|               :.:|:..::..|: :|.:..|....
plant   450 RGSIVSLPGGDGTGEADFVQA---------------SALVSQPALYSKD-LLKEHTIGPAMVHPS 498

  Fly   434 ETEQQAIRQETE--------------RFTTQLPDIETTTLFDQEIYNRSRRDVVEMMTTDAPMDT 484
            ||.:.:|..:..              :...|...|.....:..:|..::.   |.::.::..:
plant   499 ETTKGSIWHDLHDPGVKRALVVGVGLQILQQFSGINGVLYYTPQILEQAG---VGILLSNMGI-- 558

  Fly   485 TMWPEPSSSPEPIASSSLAP----PSTSVK-----------------PPLVEELL-LVVPKQEH- 526
                  |||...:..|:|..    |:.:|.                 |.|:..|| ||:....|
plant   559 ------SSSSASLLISALTTFVMLPAIAVAMRLMDLSGRRTLLLTTIPILIASLLVLVISNLVHM 617

  Fly   527 NYLVWVPL--ILLLLSAFFSHLGIRMLPWILIGEVFPAEIRNSASGFAGGVGYIFGFLANKLFLL 589
            |.:|...|  :.::|...|..:|....|.||..|:||..:|...........:|...:......:
plant   618 NSIVHAVLSTVSVVLYFCFFVMGFGPAPNILCSEIFPTRVRGICIAICALTFWICDIIVTYSLPV 682

  Fly   590 MLSALTLPGTFAFYASVAFFGTVVLYFTLPETEGRTLGEIEAHFS 634
            :|.::.|.|.|..||.|.....|.::..:|||:|..|..|...||
plant   683 LLKSIGLAGVFGMYAIVCCISWVFVFIKVPETKGMPLEVITEFFS 727

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31100	NP_001262395.1	MFS	59..>232	CDD:119392	46/185 (25%)
		Sugar_tr	98..633	CDD:278511	144/724 (20%)
		MFS	<531..616	CDD:119392	20/86 (23%)
TMT2	NP_001190923.1	MFS	14..>174	CDD:421695	39/159 (25%)
TMT2	NP_001190923.1	MFS	<516..713	CDD:421695	40/207 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000