Protein Alignment CG31100 and SLC2A10

DIOPT Version :9

• Sequence 1: NP_001262395.1
• Gene: CG31100 / 41075
• FlyBaseID: FBgn0051100
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: XP_011527362.1
• Gene: SLC2A10 / 81031
• HGNCID: 13444
• Length: 562
• Species: Homo sapiens
• Alignment Length: 650
• Identity: 149/650 - (22%)
• Similarity: 235/650 - (36%)
• Gaps: 172/650 - (26%)

  Fly    48 LPQFLAVSIKNILLFGYGMTLGFPTIVIPAIQGGEGRSETSGDIL-LNKD------EISWFSSIN 105
            ||...:||:...|.|||.:.:                  .||.:| |..|      |..:.....
Human    29 LPLCASVSLLGGLTFGYELAV------------------ISGALLPLQLDFGLSCLEQEFLVGSL 75

  Fly   106 LICVPLGCLFSGLLTQPLGKRRAMQFVNLPILAAWLMFHFATRTEHLYAALCLAGLGGGLMEAPV 170
            |:...|..|..|.|....|:::|:...||.:||..|....|.....|.....:.|....|.....
Human    76 LLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMAC 140

  Fly   171 LTYVAEITEPKYRGILSALGTTCVITGVFIQFIL-----GSLMDWRSVAAVSSAFPVITIIMLCF 230
            ..||:|:..|:.||:|.:|....:..|:.:.:.|     |:...||.:...::|..|:..:.|.|
Human   141 CIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYALAGTPWGWRHMFGWATAPAVLQSLSLLF 205

  Fly   231 VPESPVWLIREQRFREAVKSLQWLRGWVPEHMIEAEFNQLYDELITQK-AIELSADGIPPPGQRR 294
            :|...                                    ||..|.| .|.|.....|..|..|
Human   206 LPAGT------------------------------------DETATHKDLIPLQGGEAPKLGPGR 234

  Fly   295 TLGQRLRMWRKRSFL-----VPFLLVSFSFFTGHFSGKTPLQTYAVQIFHTLKAPMNKYH----- 349
            .....|.::|.|..:     |...||.|...|    |:..:..||..||.::     .:|
Human   235 PRYSFLDLFRARDNMRGRTTVGLGLVLFQQLT----GQPNVLCYASTIFSSV-----GFHGGSSA 290

  Fly   350 --ATILLGVAEMLATILGVVLIHFTGKRPLVL-------VSTVGTGLCFF------GTATYAHFL 399
              |::.||..::.||:..:.|:...|:|.|:|       :|..|.||..|      |.:..|
Human   291 VLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMALSVSGIGLVSFAVPMDSGPSCLA--- 352

  Fly   400 SEVPGFTVNNVVVNASSIMPKEGILSQQNISKIFETEQQAIRQETERFTTQLPDIETTTLFDQEI 464
              ||..|       ..:.:|.:..|.|.                     :.||.|..|
Human   353 --VPNAT-------GQTGLPGDSGLLQD---------------------SSLPPIPRT------- 380

  Fly   465 YNRSRRDVVEMMTTDAPMDTTMWPEPSSSPEPIASSSLAPPSTSVK-----PPLVEELLLVVPKQ 524
             |..:|:         |:.:|   ...:.|.|.:....|||..::.     |||        |.:
Human   381 -NEDQRE---------PILST---AKKTKPHPRSGDPSAPPRLALSSALPGPPL--------PAR 424

  Fly   525 EHNYLVWVPLILLL--LSAFFSHLGIRMLPWILIGEVFPAEIRNSASGFAGGVGYIFGFLANKLF 587
            .|..|.|..|:.|:  :|||  ..|...:.|:::.|::|.|||..|..|.....:......:..|
Human   425 GHALLRWTALLCLMVFVSAF--SFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSF 487

  Fly   588 LLMLSALTLPGTFAFYASVAFFGTVVLYFTLPETEGRTLGEIEAHFSKKS-DVNLLRKQPSNKLP 651
            |.::..:.|..||..|...|..|...:|..:|||:|::|.||:..|.|:. .::...:|.|..:|
Human   488 LDLIGTIGLSWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQKRRFTLSFGHRQNSTGIP 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31100	NP_001262395.1	MFS	59..>232	CDD:119392	43/184 (23%)
		Sugar_tr	98..633	CDD:278511	130/572 (23%)
		MFS	<531..616	CDD:119392	23/86 (27%)
SLC2A10	XP_011527362.1	Sugar_tr	32..533	CDD:278511	142/626 (23%)
		MFS	35..518	CDD:119392	135/608 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	69	1.000	Domainoid score	I9615
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D524131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820