Protein Alignment CG31100 and SLC2A2

DIOPT Version :9

• Sequence 1: NP_001262395.1
• Gene: CG31100 / 41075
• FlyBaseID: FBgn0051100
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_000331.1
• Gene: SLC2A2 / 6514
• HGNCID: 11006
• Length: 524
• Species: Homo sapiens
• Alignment Length: 641
• Identity: 130/641 - (20%)
• Similarity: 219/641 - (34%)
• Gaps: 205/641 - (31%)

  Fly    38 DVEVSNFRRALPQFLAVSIKNILLFGYGMTLGFPTIVIPAIQGGEGRSETSGDILLNKDEIS--- 99
            |:.|.|    .||       .:::..|...||.|.         :.|...:..::.:.||:.
Human    27 DIGVIN----APQ-------QVIISHYRHVLGVPL---------DDRKAINNYVINSTDELPTIS 71

  Fly   100 -------------------------WFSSINLICV--PLGCLFSGLLTQPLGKRRAMQFVN-LPI 136
                                     |..|::...|  .....|.|.|...||:.:||...| |.:
Human    72 YSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSL 136

  Fly   137 LAAWLMFHFATRTEH--LYAALCLAGLGGGLMEAPVLTYVAEITEPKYRGILSALGTTCVITGVF 199
            :.|.||........|  :.|...::||..||:...|..|:.||.....||.|.......::||:.
Human   137 VGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGIL 201

  Fly   200 I------QFILGSLMDWRSVAAVSSAFPVITIIMLCFVPESPVWL-IREQRFREAVKSLQWLRGW 257
            |      :||||:...|..:..:|....::..::|.|.||||.:| |:.....:|.:||:.|||
Human   202 ISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRG- 265

  Fly   258 VPEHMIEAEFNQLYDELITQKAIELSADGIPPPGQRRTLGQRLRMWRKRSFLVPFLLVSFSFFTG 322
                         ||: :|:...|:..:......:::.  ..::::...|:..|.|:........
Human   266 -------------YDD-VTKDINEMRKEREEASSEQKV--SIIQLFTNSSYRQPILVALMLHVAQ 314

  Fly   323 HFSGKTPLQTYAVQIFHTLKAPMNK-YHATILLGVAEMLATILGVVLIHFTGKRPLVLVSTVGTG 386
            .|||...:..|:..||.|  |.::| .:|||.:|...|:.|.:.|.|:...|:|.|.|:...|..
Human   315 QFSGINGIFYYSTSIFQT--AGISKPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMF 377

  Fly   387 LCFFGTATYAHFLSEVPGFTVNNVVVNASSIMPKEGILSQQNISKIFETEQQAIRQETERFTTQL 451
            :|       |.|:|      |..|::|
Human   378 VC-------AIFMS------VGLVLLN-------------------------------------- 391

  Fly   452 PDIETTTLFDQEIYNRSRRDVVEMMTTDAPMDTTMWPEPSSSPEPIASSSLAPPSTSVKPPLVEE 516
                                                                             
Human   392 ----------------------------------------------------------------- 391

  Fly   517 LLLVVPKQEHNYLVWVPLILLLLSAFFSHLGIRMLPWILIGEVFPAEIRNSASGFAGGVGYIFGF 581
                    :.:::.:|.:|.:.|...|..:|...:||.::.|.|....|.:|...|....:...|
Human   392 --------KFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNF 448

  Fly   582 LANKLFLLMLSALTLPGTFAFYASVAFFGTVVLYFTLPETEGRTLGEIEAHFSKKS 637
            :. .|....::....|..|..:|.|....|:..:|.:|||:|::..||.|.|.|||
Human   449 IV-ALCFQYIADFCGPYVFFLFAGVLLAFTLFTFFKVPETKGKSFEEIAAEFQKKS 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31100	NP_001262395.1	MFS	59..>232	CDD:119392	46/211 (22%)
		Sugar_tr	98..633	CDD:278511	114/575 (20%)
		MFS	<531..616	CDD:119392	19/84 (23%)
SLC2A2	NP_000331.1	Sugar_tr	14..499	CDD:278511	126/635 (20%)
		MFS	98..485	CDD:119392	106/530 (20%)
		Monosaccharide binding. /evidence=ECO:0000250|UniProtKB:P11166	314..320		3/5 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920