DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31100 and slc2a12

DIOPT Version :9

Sequence 1:	NP_001262395.1	Gene:	CG31100 / 41075	FlyBaseID:	FBgn0051100	Length:	716	Species:	Drosophila melanogaster
Sequence 2:	NP_956832.1	Gene:	slc2a12 / 393510	ZFINID:	ZDB-GENE-040426-1513	Length:	610	Species:	Danio rerio

Alignment Length:	693	Identity:	146/693 - (21%)
Similarity:	247/693 - (35%)	Gaps:	188/693 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 QNGNGGRIATSDVEVSNFRRALPQFLAVSIKNILLFGYGMTLGFPTIVIPAIQGGEGRSETSGDI 91
            ::|||..:....|             :|:..:.||.||.|:|                  .||.:
Zfish    36 KSGNGRALVLCSV-------------SVACLSGLLMGYEMSL------------------ISGAL 69

  Fly    92 LLNKDEISWFSSINLICVP----LGCLFSGLLTQPLGKRRAMQFVNLPILAAWLMFHFATR-TEH 151
            |..:|.::      |.|..    :|.|..|.....||             ...::.|:..| |..
Zfish    70 LQLRDVLT------LSCPEQEQVVGSLLLGAFLLSLG-------------GGTILDHYGRRFTII 115

  Fly   152 LYAALC---------------------LAGLGGGLMEAPVLTYVAEITEPKYRGILSALGTTCVI 195
            |.|.||                     |.|:...|.......|.||:....:||....:....|:
Zfish   116 LTALLCVLGTLLSVCVVSFWALVVGRMLVGMSVALSGTASCLYAAEVAPAAWRGRCVCVYELMVV 180

  Fly   196 TGVFIQFIL-----GSLMDWRSVAAVSSAFPVITIIMLCFVPESPVWLIREQRFREAVKSLQWLR 255
            .|:.:.|.|     |....||.....:....::...::..:|:||.:|:.:||.:||..:|..||
Zfish   181 LGMLLGFGLSWAFAGVPDGWRFTFGGALLPALLQAGVMPLLPDSPRFLLAQQREKEAHATLLRLR 245

  Fly   256 GWVPEHMIEAEFNQLYDELITQKAIELSADGIPPPGQRRTLGQRLRMWRKRSFLVPFLLVSFSF- 319
            ..:      .|...:.|||   :||.|:.      |..|..| .|.:::.|..::..|||..:.
Zfish   246 AGI------KEVEPVEDEL---RAIRLAM------GAERLHG-FLDLFQSRDNMLQRLLVGAALV 294

  Fly   320 FTGHFSGKTPLQTYAVQI-----FHTLKAPMNKYHATIL---LGVAEMLATILGVVLIHFTGKRP 376
            |....:|:..:..||..:     ||..:|      ||:.   .||.::..||..:.|:...|.:.
Zfish   295 FLQQATGQPNILAYASTVLSSVGFHGNEA------ATLASTGFGVVKVGGTIPAIFLVDKVGPKA 353

  Fly   377 L-------VLVSTVGTGLCFFGTATYAHFLSEVPGFTVNNVVVNASS------------IMPKEG 422
            |       :::||...|.....:.|:...|...||.|.|..:.....            ..|:..
Zfish   354 LLCVGVVVMMLSTATLGAITMQSRTHVSSLCRGPGNTANFTLFETGDETDIQTNTPLGLYQPQNK 418

  Fly   423 ILSQQNISKIFETEQQAIRQETERFTTQLPDIETTTLFDQEIYNRSRRDVVEMMTTDAPMDTTMW 487
            :.:...::.|.:|.:..|...|....|.|  |||..|        |::|..:
Zfish   419 LKTNAFLTSINDTREHWILNHTYDHRTAL--IETAEL--------SKKDSAK------------- 460

  Fly   488 PEPSSSPEPIASSSLAPPSTSVKPPLVEELLLVVPKQEHNYLVWVPLILLLLSAFFSHLGIRMLP 552
                     ||..||...|.|:|                    |:.|:.||:......:.:..:.
Zfish   461 ---------IALQSLHEVSPSLK--------------------WISLVSLLVYVAGFSISLGPMV 496

  Fly   553 WILIGEVFPAEIRNSASGFAGGVGYIFGFLANKLFLLMLSALTLPGTFAFYASVAFFGTVVLYFT 617
            .:::..:||..||..|........:....|.:..||.:...:.||.....|::::|...|.:...
Zfish   497 HVVLSAIFPTGIRGKAVSVISAFNWATNLLISMTFLTLTERIGLPTVIFSYSAMSFLLVVFVIVF 561

  Fly   618 LPETEGRTLGEIEAHFSKKSDV--NLL---RKQPSNKLPIKDE 655
            :|||:||:|.:|....:.|:.:  .||   ||..:...|.::|
Zfish   562 VPETKGRSLEQISKELAMKNHLRGTLLCHRRKHKAIAQPSQEE 604

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31100	NP_001262395.1	MFS	59..>232	CDD:119392	39/203 (19%)
		Sugar_tr	98..633	CDD:278511	124/593 (21%)
		MFS	<531..616	CDD:119392	17/84 (20%)
slc2a12	NP_956832.1	MFS	48..395	CDD:119392	92/418 (22%)
slc2a12	NP_956832.1	SP	49..573	CDD:273317	134/634 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820