Protein Alignment CG31100 and Slc2a6

DIOPT Version :9

• Sequence 1: NP_001262395.1
• Gene: CG31100 / 41075
• FlyBaseID: FBgn0051100
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_766247.2
• Gene: Slc2a6 / 227659
• MGIID: 2443286
• Length: 497
• Species: Mus musculus
• Alignment Length: 595
• Identity: 144/595 - (24%)
• Similarity: 228/595 - (38%)
• Gaps: 140/595 - (23%)

  Fly    41 VSNFRRALPQFLAVSIKNILLFGYGMTLGFPTIVIPAIQGGEGRSETSGDILLNKDEI--SWFSS 103
            :.|.|..|..|.|| :.|   |.:|..|.:.:.|||.:       :.|.|..|:.|:|  |||.|
Mouse    32 LKNRRVFLATFAAV-LGN---FSFGYALVYTSPVIPEL-------KLSSDPALHLDKIQASWFGS 85

  Fly   104 INLICVPLGCLFSGLLTQPLGKRRAMQFVNLPILAAWLMFHFATRTEHLYAALCLAGLGGGLMEA 168
            :..:....|.|.:.||...||::.::.|..:|....:.:...|.....|.....|.|..|||..|
Mouse    86 VFTLGAAAGGLSAMLLNDLLGRKLSIMFSAVPSAIGYAIMAGARGLWMLLLGRMLTGFAGGLTAA 150

  Fly   169 PVLTYVAEITEPKYRGILSALGTTCVITGVFIQFILGSLMDWRSVAAVSSAFPVITIIMLCFVPE 233
            .:..||:||..|..||.|.|......:.|....:.||.|:.||.:|.......:|.|::|.|:|.
Mouse   151 CIPVYVSEIAPPDVRGALGATPQLMAVFGSLSLYALGLLLPWRWLAVAGEGPVLIMILLLSFMPN 215

  Fly   234 SPVWLIREQRFREAVKSLQWLRGWVPEHMIEAEFNQLYDELITQKAIELSADGIPPPGQRRTLGQ 298
            ||.:|:.:.|..||:::|.|||.   :..:..||.|:.|.:..|.:....|:...|
Mouse   216 SPRFLLSKSRDEEALQALTWLRA---DSEVHWEFEQIQDNVRRQSSRVSWAEAREP--------- 268

  Fly   299 RLRMWRKRSFLVPFLLVSFSFFTGHFSGKTPLQTYAVQIFHTLKAPMNKYHATILLGVAEMLATI 363
              |::|      |.|:.....|....:|.||:..|...||......:.......::|...:|:.:
Mouse   269 --RVYR------PVLIAVLMRFLQQLTGITPILVYLQTIFDNTSVVLPSQQDAAIVGAVRLLSVL 325

  Fly   364 LGVVLIHFTGKRPLVLVSTVGTGLCFFGTATYAHFLSEVPGFTVNNVVVNASSIMPKEGILSQQN 428
            :..|.:...|::.|:.||                                 :|:|
Mouse   326 IAAVTMDLAGRKVLLYVS---------------------------------ASVM---------- 347

  Fly   429 ISKIFETEQQAIRQETERFTTQLPDIETTTLFDQEIYNRSRRDVVEMMTTDAPMDTTMWPEPSSS 493
                              |...|    |..|:.|.:
Mouse   348 ------------------FAANL----TLGLYVQFV----------------------------- 361

  Fly   494 PEPIASSSLAPPSTSVKPPLVEELLLVVPKQEHNYLVWVPLILLLLSAFFSHLGIRMLPWILIGE 558
            |.|     |.|.||      ||  ::.:.....|||..:||:..:|......:|...:.|:|:.|
Mouse   362 PRP-----LTPNST------VE--IVTLGDTAFNYLTLIPLLATMLFIMGYAMGWGPITWLLMSE 413

  Fly   559 VFPAEIRNSASGFAGGVGYIFGFLANKLFLLMLSALTLPGTFAFYASVAFFGTVVLYFTLPETEG 623
            |.|...|..|||....|.::..|:....|||.::|..|...|.|::::.....:.....:|||.|
Mouse   414 VLPLRARGVASGLCVLVSWLTAFVLTNYFLLAVNAFGLQVPFFFFSAICLLSLLFTGCCVPETRG 478

  Fly   624 RTLGEIEAHF 633
            |:|.:|||.|
Mouse   479 RSLEQIEAFF 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31100	NP_001262395.1	MFS	59..>232	CDD:119392	51/174 (29%)
		Sugar_tr	98..633	CDD:278511	126/536 (24%)
		MFS	<531..616	CDD:119392	22/84 (26%)
Slc2a6	NP_766247.2	Dileucine internalization motif. /evidence=ECO:0000255	5..6
		MFS	38..483	CDD:391944	138/582 (24%)
		Monosaccharide binding. /evidence=ECO:0000250|UniProtKB:P11166	284..290		1/5 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920