DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31100 and srx-118

DIOPT Version :9

Sequence 1:	NP_001262395.1	Gene:	CG31100 / 41075	FlyBaseID:	FBgn0051100	Length:	716	Species:	Drosophila melanogaster
Sequence 2:	NP_496675.2	Gene:	srx-118 / 188681	WormBaseID:	WBGene00006009	Length:	328	Species:	Caenorhabditis elegans

Alignment Length:	386	Identity:	80/386 - (20%)
Similarity:	138/386 - (35%)	Gaps:	143/386 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 ILAAWLMFHFATRTEHLYAA--LCLAGLGGGLMEAPVLTYVA---EITEPKYRGIL-----SALG 190
            :|..:|...|:|.:....:|  |.:..:.|.:|.  ||.::|   .:|  |..|.|     ::.|
Worm     4 VLDEFLYSEFSTPSTRTVSAVMLIVVSIIGSIMN--VLIFIATFFRVT--KRDGFLKICCFNSFG 64

  Fly   191 TTCVITGVFIQFILGSLMDWRSVAAVSSAFPVITIIMLCFVPESPV--WLIREQRFREAV-KSLQ 252
             :|::       .:|.|           ||||.::::     |.|.  ||      ..|: :.:.
Worm    65 -SCIV-------CIGYL-----------AFPVPSLLL-----EDPPNHWL------NAAMGQFIA 99

  Fly   253 WLRGWV--PEHMIEAEFNQL---YDELITQKAIELSADGIPPPGQRRTLGQRLRMWRKRSFLVPF 312
            |. ||.  |...|....|::   |..|:..|....:...:       .:|        .||.|.|
Worm   100 WF-GWSIGPLSQILLTVNRIIAVYFPLLYMKKYRYNPTNV-------GIG--------FSFFVAF 148

  Fly   313 -LLVSF------SFFTGHFSGKTPLQTYAVQIFHTLKAPMNKYHATILLGVAEMLATILGVVL-- 368
             |||||      ..|...:.|.....|..:.|       |.|....:::.:. .|.|...|:|
Worm   149 ILLVSFFPEGCHYLFNRDYLGWVGEFTPCIDI-------MQKTFLVVMMTIC-ALTTCCSVLLFI 205

  Fly   369 ---IHFTGKRP------------------------LVLVSTVGTGLCF---------FGTATYAH 397
               ||....|.                        |::|.::.:.:.:         |.|.:::.
Worm   206 KLIIHSPNFRVSNAQLANRHRKNRKLIIQAIVQSILIIVDSLNSTITYNLFPNLFFQFITLSFSM 270

  Fly   398 -FLSEVPGF-------TVNNVV-------VNASS--IMPKEGI-LSQQNISKIFETEQQAI 440
             ||..:.||       |:|..|       .:||:  |:||..: ..|:|.::    :.|:|
Worm   271 VFLRTLEGFVVFSINETINEEVKKMLRMKSSASNVFIVPKRSMSTGQRNYAR----QSQSI 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31100	NP_001262395.1	MFS	59..>232	CDD:119392	23/105 (22%)
		Sugar_tr	98..633	CDD:278511	80/386 (21%)
		MFS	<531..616	CDD:119392
srx-118	NP_496675.2	7TM_GPCR_Srx	27..285	CDD:370981	62/315 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010