Protein Alignment CG31100 and SLC2A13

DIOPT Version :10

• Sequence 1: NP_731299.1
• Gene: CG31100 / 41075
• FlyBaseID: FBgn0051100
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_443117.3
• Gene: SLC2A13 / 114134
• HGNCID: 15956
• Length: 648
• Species: Homo sapiens
• Alignment Length: 707
• Identity: 155/707 - (21%)
• Similarity: 264/707 - (37%)
• Gaps: 167/707 - (23%)

  Fly     6 AATAG-----ATAEKNGSLNDRPLFMQNGNGGRIATSDVEVSNFRR----ALPQFLAVSIKNILL 61
            |:.||     |.||.:.||       |:...|.....|:|.:..|:    ..|.|:.|    :.:
Human    33 ASAAGECSLLAAAESSTSL-------QSAGAGGGGVGDLERAARRQFQQDETPAFVYV----VAV 86

  Fly    62 FGY--GMTLGFPTIVIPAIQGGEGRSETSGDILLNKDEIS----W---FSSINLICVPLGCLFSG 117
            |..  |...|:.|.|:            ||.:||.|.::|    |   ..|..:....:..|..|
Human    87 FSALGGFLFGYDTGVV------------SGAMLLLKRQLSLDALWQELLVSSTVGAAAVSALAGG 139

  Fly   118 LLTQPLGKRRAMQFVNLPILAAWLMFHFATRTEHLYAALCLAGLGGGLMEAPVLTYVAEITEPKY 182
            .|....|:|.|:...:....|...:...|...|.|.|...:.|||.|:....|..|:||::.|..
Human   140 ALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNL 204

  Fly   183 RGILSALGTTCVITGVFIQFILGSLMD------WRSVAAVSSAFPVITIIMLCFVPESPVWLIRE 241
            ||.|..:.|..:..|.|...::.....      ||.:..:::...||......|:||||.|||::
Human   205 RGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGFLFLPESPRWLIQK 269

  Fly   242 QRFREAVKSLQWLRGWVPEHMIEAEFNQLYDELITQKAIELSADG--------IPPPGQRRTLGQ 298
            .:.::|.:.|..:||   ...|:.|::.:.:. |.::..|:.:.|        .||..:...:|.
Human   270 GQTQKARRILSQMRG---NQTIDEEYDSIKNN-IEEEEKEVGSAGPVICRMLSYPPTRRALIVGC 330

  Fly   299 RLRMWRKRSFLVPFLLVSFSFFTGHFSGKTPLQTYAVQIFHTLKAPMNKYHATILLGVAEMLA-- 361
            .|:|:::                  .||...:..|:..|........::    :.:.:|.:.|
Human   331 GLQMFQQ------------------LSGINTIMYYSATILQMSGVEDDR----LAIWLASVTAFT 373

  Fly   362 ----TILGVVLIHFTGKRPLVLVSTVGTGLCFFGTATYAHFLSEV-PGFTVNNVV---------- 411
                |::||.|:...|:|.|...|..||.:.....|......::| |..|...:.
Human   374 NFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSPRITFKPIAPSGQNATCTR 438

  Fly   412 ---VNASSIMPKEGILSQQNISKIFETEQQAIRQETERFTTQLPDIETTTLFDQEIYNRSRRDVV 473
               .|...:.|..|...:.|.|.:.:             ::.:|..:.:|  ::..:.|...: .
Human   439 YSYCNECMLDPDCGFCYKMNKSTVID-------------SSCVPVNKAST--NEAAWGRCENE-T 487

  Fly   474 EMMTTDAPMDTTMWPEPSSSPEPIASSSLAPPSTSVKPPLVEELLLVVPKQEHNYLVWVPLILLL 538
            :..|.|........|.|.|                                      |..|:.|:
Human   488 KFKTEDIFWAYNFCPTPYS--------------------------------------WTALLGLI 514

  Fly   539 LSAFFSHLGIRMLPWILIGEVFPAEIRNSASGFAGGVGYIFGFLANKLFLLMLSALTLPGTFAFY 603
            |...|...|:..:||.:..|::|...|::.:..:.|:.:||..|.:..||.....||..|.|..|
Human   515 LYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLY 579

  Fly   604 ASVAFFGTVVLYFTLPETEGRTLGEIEAHFSKK--------SD----VNLLRKQPSN 648
            |..|..|.:.:|..||||:|:.|.|||:.|..:        ||    :..:|.:.||
Human   580 AGFAAVGLLFIYGCLPETKGKKLEEIESLFDNRLCTCGTSDSDEGRYIEYIRVKGSN 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31100	NP_731299.1	MFS	51..628	CDD:475125	132/619 (21%)
SLC2A13	NP_443117.3	MFS_HMIT_like	87..596	CDD:340918	125/600 (21%)