Protein Alignment CG11975 and ATG21

DIOPT Version :9

• Sequence 1: NP_001262394.1
• Gene: CG11975 / 41074
• FlyBaseID: FBgn0037648
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_015225.1
• Gene: ATG21 / 856004
• SGDID: S000006021
• Length: 496
• Species: Saccharomyces cerevisiae
• Alignment Length: 488
• Identity: 98/488 - (20%)
• Similarity: 158/488 - (32%)
• Gaps: 187/488 - (38%)

  Fly    18 FNQDQG-CFACATDTGFRVYNCDPL---------KEKERQYFPEGGLSH---------------- 56
            ||||.. |...|:.....::||||.         ..|::.....|..|:
Yeast     6 FNQDATCCVVAASSHQISIFNCDPFGKCFEIDTKNSKKKTSNNNGSASNSESRNNEESILITNGS 70

  Fly    57 -----------------------------VEMLFRCNYLALVGGGIRPLYPPNKVIVWDDLKKSP 92
                                         :||||..:.:|:...| :.|....|:.:.:..:|..
Yeast    71 RDRTDAEEEEDNEDNALVTGNILKEGEFVIEMLFSTSLIAIADRG-QGLNKGKKLKIVNTKRKCT 134

  Fly    93 AISLDFNQPVRAVRLRRDRIVVVLEG---------------VIKVFTFTQQPQQLHVFETSSNPN 142
            ...:.|...:..|.:.|.|:.|:||.               .|.::....:..|.:.|..:||..
Yeast   135 ICEIVFPHEIVDVVMNRKRMCVLLESDQIFIYDISCMKPLETIDLWEDHYKRSQANSFSNASNTG 199

  Fly   143 GL-------------------------------------------CVLCPHSNKSLLAF-----P 159
            .|                                           .::..:.::|:|.|     |
Yeast   200 TLEGDSANLNRVATNLLANATQKSVNGSNPSVRTRRNSLRSKIRPRMVLSNDDRSILCFTAYSSP 264

  Fly   160 GRRTGH------VQIVDLANTERAPLEVI--AHEAGISCIALNLQGTRLATAGEKGTLIRIFDT- 215
            .:...:      |.|.|..|.  .|:..:  .|:..::|:|::..|..||||.:|||:||:|.|
Yeast   265 KKNKPNSEALYDVVIYDTLNV--TPVNYLNSVHKGNVACLAVSHDGKLLATASDKGTIIRVFHTG 327

  Fly   216 ------ESGKKVSELRRGSNHANIFCINFNHQSTMVVVASDHGTIHVFNLED------------- 261
                  .|.....|.|||:...|::.:.|:...||:....|..|||:|.|:|
Yeast   328 VDSDYMSSRSLFKEFRRGTRLCNLYQLAFDKSMTMIGCVGDTDTIHLFKLDDASNSLPGDNSSNG 392

  Fly   262 -----------------NKPRESSL--PIIPKYFSSQWSFVKFSIP--------------QGPRC 293
                             ..|:|..|  |.|..|||.:   :|.|||              :..|.
Yeast   393 HWNEEEYILASNSNPSMGTPKEIPLSKPRIANYFSKK---IKSSIPNQNLSRNFAYITVNESNRS 454

  Fly   294 VCAFGAD-PNSVVAICADGHYYKFLFNNK-GEC 324
            ...|..: ||.|.....||.:..:...:| |||
Yeast   455 CLGFPDEFPNQVYIASDDGTFSIYSIPSKPGEC 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11975	NP_001262394.1	WD40 repeat	102..136	CDD:293791	8/48 (17%)
		WD40	141..>265	CDD:421866	41/216 (19%)
		WD40 repeat	145..180	CDD:293791	9/45 (20%)
		WD40 repeat	188..225	CDD:293791	16/43 (37%)
		WD40 repeat	233..273	CDD:293791	14/71 (20%)
ATG21	NP_015225.1	WD40	<295..320	CDD:197651	10/24 (42%)
		WD40 repeat	300..343	CDD:293791	16/42 (38%)
		WD40 repeat	351..385	CDD:293791	10/33 (30%)
		WD40 repeat	393..447	CDD:293791	12/56 (21%)
		WD40 repeat	454..478	CDD:293791	6/23 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54442
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920