Protein Alignment CG11975 and ATG18

DIOPT Version :9

• Sequence 1: NP_001262394.1
• Gene: CG11975 / 41074
• FlyBaseID: FBgn0037648
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_444297.1
• Gene: ATG18 / 850577
• SGDID: S000001917
• Length: 500
• Species: Saccharomyces cerevisiae
• Alignment Length: 353
• Identity: 96/353 - (27%)
• Similarity: 155/353 - (43%)
• Gaps: 94/353 - (26%)

  Fly     3 LTEQNPYGNGLLYAAFNQDQGCFACATDTGFRVYNCDPLKEKERQYFPE--GGLSHVEMLFRCNY 65
            :::.:|..|   :..|||...|.:..|..||:::||:|.    .:::.|  ||.:.|||||..:.
Yeast     1 MSDSSPTIN---FINFNQTGTCISLGTSKGFKIFNCEPF----GKFYSEDSGGYAIVEMLFSTSL 58

  Fly    66 LALVGGGIRPLYPPNKVIVWDDLKKSPAISLDFNQPVRAVRLRRDRIVVVLEGVIKVFTFTQQPQ 130
            |||||.|.:|...|.::.:.:..|.|....:.|...:.:|::.:.|:||:|:..|.::..... :
Yeast    59 LALVGIGDQPALSPRRLRIINTKKHSIICEVTFPTSILSVKMNKSRLVVLLQEQIYIYDINTM-R 122

  Fly   131 QLHVFETSSNPNGLCVLCPHSNKSLLAFP-----------------------GRRT--------- 163
            .||..||:.||.||..:.|....|.|.:|                       |..|
Yeast   123 LLHTIETNPNPRGLMAMSPSVANSYLVYPSPPKVINSEIKAHATTNNITLSVGGNTETSFKRDQQ 187

  Fly   164 --GHVQIVDL----ANTER-----------------------------APLEVI-AHEAGISCIA 192
              ||..|.||    :.|:|                             .|..|| ||:..|:.:|
Yeast   188 DAGHSDISDLDQYSSFTKRDDADPTSSNGGNSSIIKNGDVIVFNLETLQPTMVIEAHKGEIAAMA 252

  Fly   193 LNLQGTRLATAGEKGTLIRIFDTESGKKVSELRRGSNHANIFCINFNHQSTMVVVASDHGTIHVF 257
            ::..||.:|||.:|||:||:||.|:|.|:.:.|||:....|:.|:|:..|..:.|.....|:|:|
Yeast   253 ISFDGTLMATASDKGTIIRVFDIETGDKIYQFRRGTYATRIYSISFSEDSQYLAVTGSSKTVHIF 317

  Fly   258 ----------------NLEDNKPRESSL 269
                            |:|:....:|||
Yeast   318 KLGHSMSNNKLDSDDSNMEEAAADDSSL 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11975	NP_001262394.1	WD40 repeat	102..136	CDD:293791	8/33 (24%)
		WD40	141..>265	CDD:421866	51/207 (25%)
		WD40 repeat	145..180	CDD:293791	14/101 (14%)
		WD40 repeat	188..225	CDD:293791	17/36 (47%)
		WD40 repeat	233..273	CDD:293791	13/53 (25%)
ATG18	NP_444297.1	WD40	<224..318	CDD:421866	32/93 (34%)
		WD40 repeat	249..285	CDD:293791	16/35 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54442
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R106
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.910