Protein Alignment CG11975 and wdr45

DIOPT Version :10

• Sequence 1: NP_649853.1
• Gene: CG11975 / 41074
• FlyBaseID: FBgn0037648
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: XP_012812316.2
• Gene: wdr45 / 496788
• XenbaseID: XB-GENE-972376
• Length: 355
• Species: Xenopus tropicalis
• Alignment Length: 352
• Identity: 153/352 - (43%)
• Similarity: 222/352 - (63%)
• Gaps: 29/352 - (8%)

  Fly    11 NGLLYAAFNQDQGCFACATDTGFRVYNCDPLKEK----ERQYFPEGGLSHVEMLFRCNYLALVGG 71
            |||   .|||||.||.||.:||.|::|.:||.||    :.|.   |.:..||||.|||.||||||
 Frog     8 NGL---RFNQDQSCFCCAMETGVRIFNIEPLMEKGHLDQEQV---GSVGQVEMLHRCNLLALVGG 66

  Fly    72 GIRPLYPPNKVIVWDDL---KKSPAISLDFNQPVRAVRLRRDRIVVVLEGVIKVFTFTQQPQQLH 133
            |..|.:....|::|||.   |....:...|.:||.:||||.::||:.|:..|.|::|...|.:|.
 Frog    67 GSNPKFSDISVLIWDDSRDGKDKLVLEFTFTKPVLSVRLRSEKIVIALKNRIYVYSFPDNPTKLF 131

  Fly   134 VFETSSNPNGLCVLCPHSNKSLLAFPGRRTGHVQIVDLAN----TERAPLEVIAHEAGISCIALN 194
            .|:|..||.|||.|||...|.||.|||.:.|.:|:|||.|    :..||..:.||::.:.|:|:|
 Frog   132 EFDTRDNPKGLCDLCPSLEKQLLLFPGHKCGSLQLVDLCNAKPGSSSAPFTINAHQSELGCLAVN 196

  Fly   195 LQGTRLATAGEKGTLIRIFDTESGKKVSELRRGSNHANIFCINFNHQSTMVVVASDHGTIHVFNL 259
            .|||.:|:|..||||||:|||::.:::.|||||::.|.::||||:|.|:.:..:||.||:|:|.|
 Frog   197 QQGTLVASASRKGTLIRLFDTQTREQLVELRRGTDPATLYCINFSHDSSFLCSSSDKGTVHIFAL 261

  Fly   260 EDNK-PRESSL-------PIIPKYFSSQWSFVKFSIPQGPRCVCAFGADP----NSVVAICADGH 312
            :|.| .|.|:|       |:|.:|..||||...|::|....|:||||.:.    |||:|:|.||.
 Frog   262 KDTKLNRRSALARVGKVGPMIGQYVDSQWSLASFTVPAESACICAFGKNTSKNVNSVIAVCVDGT 326

  Fly   313 YYKFLFNNKGECSRDICTQFLELQDDE 339
            ::|::|..:|.|:|:....:|::.||:
 Frog   327 FHKYVFTPEGNCNREAFDVYLDICDDD 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11975	NP_649853.1	WD40	<70..>265	CDD:441893	88/202 (44%)
		WD40 repeat	102..136	CDD:293791	13/33 (39%)
		WD40 repeat	145..180	CDD:293791	18/38 (47%)
		WD40 repeat	188..225	CDD:293791	18/36 (50%)
		WD40 repeat	233..273	CDD:293791	19/47 (40%)
wdr45	XP_012812316.2	WD40	6..259	CDD:475233	117/256 (46%)
		WD40 repeat	101..137	CDD:293791	14/35 (40%)
		WD40 repeat	142..182	CDD:293791	19/39 (49%)
		WD40	<162..>269	CDD:441893	48/106 (45%)
		WD40 repeat	191..227	CDD:293791	18/35 (51%)