DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11975 and wipi2

DIOPT Version :10

Sequence 1:NP_649853.1 Gene:CG11975 / 41074 FlyBaseID:FBgn0037648 Length:340 Species:Drosophila melanogaster
Sequence 2:NP_001314718.1 Gene:wipi2 / 437002 ZFINID:ZDB-GENE-040718-488 Length:427 Species:Danio rerio


Alignment Length:364 Identity:110/364 - (30%)
Similarity:176/364 - (48%) Gaps:51/364 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MNLTEQNPYG--NGLLYAAFNQDQGCFACATDTGFRVYNCDPLKEKERQY--FPEGGLSHVEMLF 61
            |||..|:...  :.||:|.||||....|..|.:|::.::...:.:.|:.|  .....:..||.||
Zfish     1 MNLASQSGEAGCSQLLFANFNQDNTSLAVGTKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLF 65

  Fly    62 RCNYLALVGGGIRPLYPPNKVIVWDDLKKSPAISLDFNQPVRAVRLRRDRIVVVLEGVIKVFTFT 126
            ..:.:|:|.     |..|.|:.|....|.:...:..::..:.||:|.|.|::|.||..:.:... 
Zfish    66 SSSLVAIVS-----LKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNI- 124

  Fly   127 QQPQQLH-VFETSSNPNGLCVLCPHSNKSLLAFPGRRT-GHVQIVDLANTERAPLEVIAHEAGIS 189
            :..:.|| :.||..||:|||.|...::...||:||..| |.||:.|..|. ||...:.||::.::
Zfish   125 RDMKVLHTIRETPPNPSGLCALSISNDNCYLAYPGSATIGEVQVFDTVNL-RAANMIPAHDSPLA 188

  Fly   190 CIALNLQGTRLATAGEKGTLIRIFDTESGKKVSELRRGSNHANIFC-INFNHQSTMVVVASDHGT 253
            .:|.:..||:||||.||||:||:|....|:|:.|.|||.......| :.|:.:...:..:|:..|
Zfish   189 ALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMEGLYLSASSNTET 253

  Fly   254 IHVFNLEDNKPRESSLP--------------------IIPKY----FSSQWSFVKFSIP-QGPRC 293
            :|:|.||..  ||.|:|                    .:|.:    |:...:|....:| .|.:.
Zfish   254 VHIFKLETQ--REKSVPQEEPTTWTGYFGKVLMASTTYLPAHVTEMFTQGRAFATVRLPFSGHKN 316

  Fly   294 VCAFG---ADPNSVVAICADGHYYKFLFN----NKGECS 325
            :||..   ..|..:|| .|||  |.:|:|    ..|||:
Zfish   317 ICALAIIQKIPRLLVA-AADG--YLYLYNLDPQEGGECT 352

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11975NP_649853.1 WD40 <70..>265 CDD:441893 65/197 (33%)
WD40 repeat 102..136 CDD:293791 10/34 (29%)
WD40 repeat 145..180 CDD:293791 14/35 (40%)
WD40 repeat 188..225 CDD:293791 17/36 (47%)
WD40 repeat 233..273 CDD:293791 12/60 (20%)
wipi2NP_001314718.1 WD40 repeat 58..99 CDD:293791 11/45 (24%)
WD40 <121..282 CDD:441893 56/164 (34%)
WD40 repeat 144..181 CDD:293791 14/37 (38%)
WD40 repeat 187..224 CDD:293791 17/36 (47%)
WD40 repeat 231..259 CDD:293791 6/27 (22%)

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