Protein Alignment E(var)3-9 and CG2678

DIOPT Version :9

• Sequence 1: NP_649852.2
• Gene: E(var)3-9 / 41073
• FlyBaseID: FBgn0260243
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_649750.1
• Gene: CG2678 / 40937
• FlyBaseID: FBgn0014931
• Length: 434
• Species: Drosophila melanogaster
• Alignment Length: 543
• Identity: 101/543 - (18%)
• Similarity: 171/543 - (31%)
• Gaps: 185/543 - (34%)

  Fly    18 CRTCGIYFTMGMDMDQAIVKPIFGSDDAAVAD-----MAEILEQMNDWNIKVAREDGRPQYMCIA 77
            ||||       ||....:| .||.:....|.|     ::.||.:..:..:|  |.|..||::|::
  Fly     9 CRTC-------MDETGTLV-DIFANVRDPVLDEPEMSLSHILARCTERPVK--RGDLLPQFICVS 63

  Fly    78 CIAEFHRLIKFKRSCVETQEQFGELEYQREHNGIVIKREIEPEEEKFCGFIYLDTDEEDN----- 137
            |:.......:||..        .|..||  |...|:.:...||.:........|.::..|
  Fly    64 CVLAVQNAFRFKWQ--------SEQSYQ--HFFRVLNQSGAPENQVHLAACNGDKNQIINQKMQL 118

  Fly   138 -SDEDGSRRVCAVFDIPHVPIKEEHMARVPLQNSDKFQPPE-----PKNFASPVDSRFDMIDNDA 196
             ||.....:.......|...:.::...:..||..:...|||     |:......:.:.|||..:|
  Fly   119 KSDRQQDTQQMTKTQKPDDDLSQKQTLQAKLQEGNIDGPPESFTLHPRKRTCRTEEQADMIPKEA 183

  Fly   197 LTSGMLGPSIEDLSGTVDDGTEDEEEEEEEIVRFTYDDDNDAAAPLPPPLYSPVVCCKLCFYESP 261
            ..|                                                :.::|
  Fly   184 TRS------------------------------------------------TKMIC--------- 191

  Fly   262 DQDAHMEHMRRTHLLKDWECHICGKKFTNAQESRIKFHIKYHKLQRHV-----KCPVCGFICSSK 321
            |.|.:            :.|..|.|:|.:..:           |:.|:     :||.|......|
  Fly   192 DADGY------------YNCPHCSKRFCSQTQ-----------LRTHITDLCNRCPYCPRTYMQK 233

  Fly   322 ETLKEH-----KQAVHVRTKCTYCGKT-VKNATLHAHLKKHLEEGEAELAQ-QLKKLEQLPVNLQ 379
            ..||.|     .:..|   ||.:|.|. ::...|..||:.|..:|....:| ....:|.:.:.:.
  Fly   234 SNLKRHLRNHLSKPAH---KCFHCSKAFMRKDHLKRHLRTHDSDGPLSCSQCSAVFIEHVQLEIH 295

  Fly   380 SQHLSSLESSVAEVTTASEGSNIPG----ESTVPEDSNVTENS-SVPSIETSNHADIQCPMGPPA 439
            .:                |....||    |||...||:.::.: .:....|.|..:..|.: ||.
  Fly   296 RR----------------EHKQRPGSSKSESTKDPDSDDSDQAQDLKPKWTKNTFNGTCSI-PPM 343

  Fly   440 NGEVPDVADVASPSTEPT-------------ESVTKCSYCSDTFEKAQQLQAH------------ 479
            ....| :.|:........             ..:.||:|||:.|:..:.|:.|
  Fly   344 LKPKP-ICDICQKKFSSVYALKRHMLTHNRQHHLKKCTYCSEEFKTEKHLKRHERGHMGDLFRCE 407

  Fly   480 ------VLATHTQTRKRRRSSDN 496
                  |...:.:..|:|..|:|
  Fly   408 FCSLVFVDVNYLRKHKKRIHSNN 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(var)3-9	NP_649852.2	zf-AD	18..102	CDD:285071	22/88 (25%)
		zf-C2H2_2	253..>334	CDD:289522	16/90 (18%)
		C2H2 Zn finger	253..274	CDD:275368	2/20 (10%)
		C2H2 Zn finger	281..303	CDD:275368	4/21 (19%)
		PHA00732	310..>358	CDD:177300	16/53 (30%)
		C2H2 Zn finger	311..332	CDD:275368	7/25 (28%)
		C2H2 Zn finger	337..356	CDD:275368	6/19 (32%)
CG2678	NP_649750.1	zf-AD	8..85	CDD:214871	25/95 (26%)
		COG5048	220..>284	CDD:227381	18/66 (27%)
		C2H2 Zn finger	223..243	CDD:275368	7/19 (37%)
		zf-C2H2	249..271	CDD:278523	8/24 (33%)
		C2H2 Zn finger	251..271	CDD:275368	6/19 (32%)
		C2H2 Zn finger	279..299	CDD:275368	2/35 (6%)
		C2H2 Zn finger	350..370	CDD:275368	1/19 (5%)
		C2H2 Zn finger	379..399	CDD:275368	7/19 (37%)
		C2H2 Zn finger	406..427	CDD:275368	3/20 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S8297
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.950