Protein Alignment E(var)3-9 and Zfp711

DIOPT Version :10

• Sequence 1: NP_649852.2
• Gene: E(var)3-9 / 41073
• FlyBaseID: FBgn0260243
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: XP_002730311.1
• Gene: Zfp711 / 302327
• RGDID: 1562768
• Length: 805
• Species: Rattus norvegicus
• Alignment Length: 704
• Identity: 134/704 - (19%)
• Similarity: 237/704 - (33%)
• Gaps: 241/704 - (34%)

  Fly    30 DMDQAIVKPIFGSDD---AAVADMAEILEQMNDWNIKV--------AREDGRPQYMCIACIAEFH 83
            |.|...||..  |:|   .::.|:.|.||.|.:..:|:        .:|||..        :|..
  Rat   190 DDDDDDVKST--SEDYLMISLDDVGEKLEHMGNTPLKIGSDGSQEDVKEDGFG--------SEVI 244

  Fly    84 RLIKFKRSCVETQEQFG-----ELEYQREHN--GIVIKREIEPEEEKFCGFIYLDTDEEDNSDED 141
            ::..||....:..|..|     |.||...|:  |::.:..::.|:     .:|:..  :|:|.|:
  Rat   245 KVYIFKAEAEDDVEIGGTEIVTESEYTSGHSVAGVLDQSRMQREK-----MVYMAV--KDSSQEE 302

  Fly   142 GSRRVCAVFDIPHVPI----KEEHMARVPLQNSDKFQPPEPKNFASPVDSR-------------- 188
            .......:.|..::.:    :|.::..:.|::||..:...|..:.:..|.|
  Rat   303 DDISYAEISDELYMEVIIGEEEGNLLEIQLEDSDVNKTVSPVVYPASYDERRVSRRYEDCQATGN 367

  Fly   189 -FD-------------------MIDNDAL----------------TSGMLGPSIEDLS------- 210
             ||                   |..|..|                |:.::||..:.|:
  Rat   368 TFDSALENRSTTAAQYLQICDSMNTNKVLKQKIKKRRRGETRQWQTAVIIGPDGQPLTVYPCHIC 432

  Fly   211 ---------------------------GTVDDGTEDEE----------------EEEEEIVRFT- 231
                                       .|..|.|.:::                ::..|...:|
  Rat   433 TKKFKSRGFLKRHMKNHPDHLMRKKYQCTDCDFTTNKKVSFHNHLESHKLINKVDKTHEFTEYTR 497

  Fly   232 -YDDDNDAAAPL----------PPPLYSPVVCCKLCFYESPDQDAHMEHMRRTHLLKDWE--CHI 283
             |.:    |:||          .|.::.    ||.|.||:.:|.....|:...| .|.:.  |..
  Rat   498 RYRE----ASPLSSNKLILRDKEPKMHK----CKYCDYETAEQGLLNRHLLAVH-SKSFPHVCVE 553

  Fly   284 CGKKFTNAQESRIKFHIKYHKLQRHVKCPVCGFICSSKETLKEHKQAVH---VRTKCTYCGKTVK 345
            |||.|.:..|  :|.|::.|..::..:|..|.|.|:.:..||.|.::.|   :..||.:|.::..
  Rat   554 CGKGFRHPSE--LKKHMRTHTGEKPYQCQYCVFRCADQSNLKTHIKSKHGNNLPYKCEHCPQSFG 616

  Fly   346 NATLHAHLKKHLE--EGEAELAQQLKKLEQLP-VNLQSQHLSSLESSVAEVTTASEGSNIPGEST 407
            :   ...|::||:  :|.        |..|.| .:.:|.:.|.|:..:..|.|          ..
  Rat   617 D---ERELQRHLDLFQGH--------KTHQCPHCDHKSTNSSDLKRHIISVHT----------KD 660

  Fly   408 VPEDSNVTENSSVPSIETSNHADIQCPMGPPANGEVPDVADVASPSTEPTESVTKCSYC----SD 468
            .|....|.:.......|...|:||                       .....:.:|.:|    ||
  Rat   661 FPHKCEVCDKGFHRPSELKKHSDI-----------------------HKGRKIHQCRHCDFKTSD 702

  Fly   469 TFEKAQQLQAHVLATHTQTRKRRRSSDNQSLVRKTTQEIPTSPIAKITKKQTIESKERVVLESSS 533
            .|    .|..|:|:.||:         :|||..|.         .|...:|..|.|:.:...:..
  Rat   703 PF----ILSGHILSVHTK---------DQSLKCKR---------CKRGFRQQNELKKHMKTHTGR 745

  Fly   534 QLDSTAQQESRTSATSNDSSPVQQVPEKAY-ISCYICGRSFDLKIKLNRHLKQH 586
            ::......|..|:..|.....|..:..|.| ..|..|.:.|....:.|:|:.:|
  Rat   746 KIYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEFCKKGFRRPSEKNQHIMRH 799

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(var)3-9	NP_649852.2	zf-AD	18..102	CDD:462262	20/87 (23%)
		zf-C2H2_2	253..>334	CDD:463690	26/85 (31%)
		C2H2 Zn finger	253..274	CDD:275368	7/20 (35%)
		C2H2 Zn finger	281..303	CDD:275368	8/21 (38%)
		PHA00732	310..>358	CDD:177300	13/50 (26%)
		C2H2 Zn finger	311..332	CDD:275368	7/20 (35%)
		C2H2 Zn finger	337..356	CDD:275368	3/18 (17%)
Zfp711	XP_002730311.1	Zfx_Zfy_act	65..412	CDD:461400	43/238 (18%)
		COG5048	425..803	CDD:227381	87/452 (19%)
		C2H2 Zn finger	429..449	CDD:275368	0/19 (0%)
		C2H2 Zn finger	522..543	CDD:275368	7/20 (35%)
		C2H2 Zn finger	551..571	CDD:275368	8/21 (38%)
		C2H2 Zn finger	579..600	CDD:275368	7/20 (35%)
		C2H2 Zn finger	608..634	CDD:275368	7/36 (19%)
		C2H2 Zn finger	636..657	CDD:275368	4/20 (20%)
		C2H2 Zn finger	665..685	CDD:275368	5/42 (12%)
		C2H2 Zn finger	722..742	CDD:275368	5/28 (18%)
		C2H2 Zn finger	750..771	CDD:275368	4/20 (20%)
		C2H2 Zn finger	779..799	CDD:275368	5/19 (26%)