Protein Alignment E(var)3-9 and Zfp711

DIOPT Version :10

• Sequence 1: NP_649852.2
• Gene: E(var)3-9 / 41073
• FlyBaseID: FBgn0260243
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_808415.2
• Gene: Zfp711 / 245595
• MGIID: 3045342
• Length: 805
• Species: Mus musculus
• Alignment Length: 672
• Identity: 130/672 - (19%)
• Similarity: 222/672 - (33%)
• Gaps: 216/672 - (32%)

  Fly    49 DMAEILEQMNDWNIKVAREDGRPQYMCIACIAEFHRLIKFKRSCVETQEQFG-----ELEYQREH 108
            |:.|.||.|.:..:|:|.:..:......|..:|..::..||....:..|..|     |.||...|
Mouse   210 DVGEKLEHMGNTPLKIASDGSQEDVKEDAFGSEVIKVYIFKAEAEDDVEIGGTEIVTESEYSSGH 274

  Fly   109 N--GIVIKREIEPEEEKFCGFIYLDTDEEDNSDEDGSRRVCAVFDIPHVPIKEEH--MARVPLQN 169
            :  |::.:..::.|:..:........:::|.|:.|.|..:|.     .|.|.||.  ...:|||:
Mouse   275 SVAGVLDQSRMQREKMVYMAVKDSSQEQDDISNADISNELCM-----EVIIGEEEGTPLEIPLQD 334

  Fly   170 SDKFQPPEPKNFASPVDSR---------------FD-------------------MIDNDAL--- 197
            .|..:...|....:..|.|               ||                   |..|..|
Mouse   335 CDVNKTGSPVLSPASYDERRVSRRYEECQAPGNTFDSALENRNTTAAQYLQICDSMNTNKVLKQK 399

  Fly   198 -------------TSGMLGPSIEDLS----------------------------------GTVDD 215
                         |:.::||..:.|:                                  .|..|
Mouse   400 IKKRRRGETRQWQTAVIIGPDGQPLTVYPCHICTKKFKSRGFLKRHMKNHPDHLMRKKYQCTDCD 464

  Fly   216 GTEDEE----------------EEEEEIVRFT--YDDDNDAAAPL----------PPPLYSPVVC 252
            .|.:::                ::..|...:|  |.:    |:||          .|.::.
Mouse   465 FTTNKKVSFHNHLESHKLINKVDKTHEFTEYTRRYRE----ASPLSSNKLILRDKEPKMHK---- 521

  Fly   253 CKLCFYESPDQDAHMEHMRRTHLLKDWE--CHICGKKFTNAQESRIKFHIKYHKLQRHVKCPVCG 315
            ||.|.||:.:|.....|:...| .|.:.  |..|||.|.:..|  :|.|::.|..::..:|..|.
Mouse   522 CKYCDYETAEQGLLNRHLLAVH-SKSFPHVCVECGKGFRHPSE--LKKHMRTHTGEKPYQCQYCA 583

  Fly   316 FICSSKETLKEHKQAVH---VRTKCTYCGKTVKNATLHAHLKKHLE--EGEAELAQQLKKLEQLP 375
            |.|:.:..||.|.::.|   :..||.:|.:...:   ...|::||:  :|.        |..|.|
Mouse   584 FRCADQSNLKTHIKSKHGSNLPYKCEHCPQAFGD---ERELQRHLDLFQGH--------KTHQCP 637

  Fly   376 -VNLQSQHLSSLESSVAEVTTASEGSNIPGESTVPEDSNVTENSSVPSIETSNHADIQCPMGPPA 439
             .:.:|.:.|.|:..:..|.|          ...|....|.:.......|...|:||
Mouse   638 HCDHKSTNSSDLKRHIISVHT----------KDFPHKCEVCDKGFHRPSELKKHSDI-------- 684

  Fly   440 NGEVPDVADVASPSTEPTESVTKCSYC----SDTFEKAQQLQAHVLATHTQTRKRRRSSDNQSLV 500
                           .....:.:|.:|    ||.|    .|..|:|:.||:         :|||.
Mouse   685 ---------------HKGRKIHQCRHCDFKTSDPF----ILSGHILSVHTK---------DQSLK 721

  Fly   501 RKTTQEIPTSPIAKITKKQTIESKERVVLESSSQLDSTAQQESRTSATSNDSSPVQQVPEKAY-I 564
            .|.         .|...:|..|.|:.:...:..::......|..|:..|.....|..:..|.| .
Mouse   722 CKR---------CKRGFRQQNELKKHMKTHTGRKIYQCEYCEYSTTDASGFKRHVISIHTKDYPH 777

  Fly   565 SCYICGRSFDLKIKLNRHLKQH 586
            .|..|.:.|....:..:|:.:|
Mouse   778 RCEFCKKGFRRPSEKKQHIMRH 799

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(var)3-9	NP_649852.2	zf-AD	18..102	CDD:462262	13/57 (23%)
		zf-C2H2_2	253..>334	CDD:463690	26/85 (31%)
		C2H2 Zn finger	253..274	CDD:275368	7/20 (35%)
		C2H2 Zn finger	281..303	CDD:275368	8/21 (38%)
		PHA00732	310..>358	CDD:177300	13/50 (26%)
		C2H2 Zn finger	311..332	CDD:275368	7/20 (35%)
		C2H2 Zn finger	337..356	CDD:275368	3/18 (17%)
Zfp711	NP_808415.2	Zfx_Zfy_act	65..412	CDD:461400	40/206 (19%)
		COG5048	425..805	CDD:227381	86/452 (19%)
		C2H2 Zn finger	429..449	CDD:275368	0/19 (0%)
		C2H2 Zn finger	522..543	CDD:275368	7/20 (35%)
		C2H2 Zn finger	551..571	CDD:275368	8/21 (38%)
		C2H2 Zn finger	579..600	CDD:275368	7/20 (35%)
		C2H2 Zn finger	608..634	CDD:275368	7/36 (19%)
		C2H2 Zn finger	636..657	CDD:275368	4/20 (20%)
		C2H2 Zn finger	665..685	CDD:275368	5/42 (12%)
		C2H2 Zn finger	722..742	CDD:275368	5/28 (18%)
		C2H2 Zn finger	750..771	CDD:275368	4/20 (20%)
		C2H2 Zn finger	779..799	CDD:275368	4/19 (21%)