Protein Alignment CG11970 and Nfrkb

DIOPT Version :9

• Sequence 1: NP_001287243.1
• Gene: CG11970 / 41072
• FlyBaseID: FBgn0027503
• Length: 1658
• Species: Drosophila melanogaster
• Sequence 2: XP_038937300.1
• Gene: Nfrkb / 315523
• RGDID: 1310558
• Length: 1310
• Species: Rattus norvegicus
• Alignment Length: 1562
• Identity: 414/1562 - (26%)
• Similarity: 644/1562 - (41%)
• Gaps: 398/1562 - (25%)

  Fly    98 SDELELAQ-------------LTGRDIFRLPRGLCENAAIFHEFFSLETWQQ-LPHHLQARLQPM 148
            :|.|||..             |.|.....||..|.|:..||.:..||.|||: |....:..||..
  Rat     9 TDPLELGPCGDGHSTGIMEDCLLGGTRVSLPEDLLEDPEIFFDVVSLSTWQEVLSDSQREHLQQF 73

  Fly   149 LPDFSRLVSGQAQACAEQQRTLVQLFNGGLQRFGQSPLLQLQRQLEEGNLRPDVLQLRRSIQHSG 213
            ||.|      ......:|...::.||:|...||| :||...|:...:|:..|:|::.|:....|.
  Rat    74 LPQF------PTDTVEQQNELILALFSGENFRFG-NPLHIAQKLFRDGHFNPEVVKYRQLCFKSQ 131

  Fly   214 RREFRFQQAERLSLLAKELFMSREQLLQHAYTSAPPSDGAFGKNLPRPRSRKRKPPTLSIENKFC 278
            .:.:...|.:....|.:::..||..||:.|.||.|          ..|...|...|:.|.|.:
  Rat   132 YKRYLSSQQQYFHRLLRQILASRSDLLEMARTSGP----------ALPFRHKHHSPSRSPEER-- 184

  Fly   279 SQRAKKRYAQELLELIGSLEAKPGDISAEEEEEDEECRQLMDRLAKGPQEFELEETKAPEPAGPG 343
            ..|.::||    |:::..::.:.||.:...:||.....|         ::|..|:..:..|:.|.
  Rat   185 EWRTQQRY----LKVLREVKEECGDTALSSDEEATLDLQ---------EKFSFEDLSSWLPSSPA 236

  Fly   344 R-PSNAADKKCIYNTFFKRRPGVDDDLVLRSMQ-AEKIPKLNDKNFRKYLRDYKRRKLEQPESPE 406
            | ||.|...:.:            ..|....|: |:|| :|.|.:.:..|:.:..::..||:.|:
  Rat   237 RSPSPAVPLRVV------------PTLSTTDMKTADKI-ELGDSDLKLMLKKHHEKRKHQPDHPD 288

  Fly   407 FDTSEVRLRDICTRAQFVGSFKPGRKPKALMARLNPDPPALVPIGVTPTKNEFVDEEPMLLDEPQ 471
            ..|.::.|.||.||.      ..|||...         .||..:.|...|
  Rat   289 LLTGDLTLSDIMTRV------NAGRKGSL---------AALYDLAVLKKK--------------- 323

  Fly   472 QLYGRRAPEDHPEEDLPHKEPPPMPK-KVMPAPVVLPQPVPKLEPLNGPITNPKASPTTPNHSNN 535
                           :..||.....| |::.:         :.|.|..|::|.:..||. :.:.:
  Rat   324 ---------------VKEKEEKKKKKIKLIKS---------EAEDLAEPLSNTEGVPTL-SQAPS 363

  Fly   536 PITVSATAGHITGSPTREVQIRPPASPRPACFFSLLRDLFVSTPQHRLTYGELQILLSSWREINS 600
            |:.:|:    |...|..:::.....:...:.|||||.::.:...|..|...|.::|  .|:  :|
  Rat   364 PLAISS----IKEEPLEDIKPCLGINEISSSFFSLLLEILLLESQASLPMLEDRVL--DWQ--SS 420

  Fly   601 DASIPIGEWPRFRPDWSKLLQSAINFLSGDFSSVPADYVPYIEHKTQLGIYQWIGAGRDSDARLL 665
            .|| .:..|....|:|::|:..|:.:|:|:..:||:.:.|::|.|.:...::.:|..:|::..|.
  Rat   421 PAS-SLNSWFSAAPNWAELVLPALQYLAGESRAVPSSFSPFVEFKEKTQQWKLLGQSQDNEKELA 484

  Fly   666 SLCQFWLRTQRE---KQSQLSPVLISGVHLNSLVDASPTPPPRCPTTWTVRSATQAEILEFQSQE 727
            :|...||.|:.:   ||.            |.....:.||.||..|.:.||.:|..|...||.||
  Rat   485 ALFHLWLETKDQAFCKQE------------NEDSSDAMTPVPRVRTDYVVRPSTGEEKRVFQEQE 537

  Fly   728 RIRFEYPHRPFTYRLNGYESVVGPVKGIYTQGLPLNKARGHAVMVDDRPPFVTILTLVRDATARL 792
            |.|:..||:.||:|::|:|||||||||::.:...|||||.|:::..|||.:||||:|||||.|||
  Rat   538 RYRYSQPHKAFTFRMHGFESVVGPVKGVFDKETSLNKAREHSLLRSDRPAYVTILSLVRDAAARL 602

  Fly   793 PNGEGTRSEISELLKCSQYISQQAADNVLQTIVSGALDRMHGGPDPCVKYDARRKIWIYLHRNRS 857
            |||||||:||.||||.||:::.......:.|:|||||||:|...|||||||..||:||||||:||
  Rat   603 PNGEGTRAEICELLKDSQFLAPDVTSTQVNTVVSGALDRLHYEKDPCVKYDIGRKLWIYLHRDRS 667

  Fly   858 EAEFEKMHRHNQSLVKQK---QQQRKQLNRPKIPDDR---SGLAADHQQEQV------------- 903
            |.|||::|:...:..|.:   ||:.|..::.|..:..   .||:...:..|:
  Rat   668 EEEFERIHQAQAAAAKARKALQQKPKPPSKVKSSNKEGSVKGLSGPSEPSQMSLSDSSMPPTPVT 732

  Fly   904 ------PALVPAVASPVPVS---------VQQPVVASLQMKKPLAVKCPPVP-------PLKYHV 946
                  ||| |...||.|||         |.:|..:|..:   |.|..|.:|       |.....
  Rat   733 PVTPTTPAL-PTPISPPPVSAVSRSGSTTVSEPAKSSSGV---LLVSSPTMPQLGTMLSPASIQT 793

  Fly   947 PPGTPIGGTIISASSNINANQIPMQQIQKSLLKPVVVPNS-APSPVQRQLATGKS----GTFAIS 1006
            ||.:.....::|.||:....|:.: ..|.||  |.|...| .|:....|:..|..    .|...:
  Rat   794 PPSSQTTARVVSHSSSAGLPQVRV-VAQPSL--PAVSQQSVGPAQPLPQMPAGPQIRVPVTATQT 855

  Fly  1007 KISPTR---------NTTPILVSTPSGLQT------VHVATTPN-----QAGGSASPTVAKKLTI 1051
            |:.|..         .||...|..|...||      :..|.:|.     .:.||::|:.:....|
  Rat   856 KVVPQAVVATVPVKGQTTAASVQRPGPAQTGLTVTSLPAAVSPGSKTAMSSPGSSAPSASTTAVI 920

  Fly  1052 KKPVPNNKIGNFIIPLDQQQSGPQQQQPTQQGQHVKVQPIAGKPKALTITPRPQMPKNIIRLLPA 1116
            :     |..|..||           :|.:..|| :.|:|..|....||.|......|:::||.|:
  Rat   921 Q-----NVTGQNII-----------KQVSITGQ-LGVKPQTGNSIPLTATNFRIQGKDVLRLPPS 968

  Fly  1117 GGAT-VTGNSVIGGTKPNSVQILGPRVVPQIQTVRPAQQKIGAVSIVANKPVTS--------VAA 1172
            ...| ..|.:|:..| |:.:..|..   .|:.||:..|...||.|..|.|.:::        |.|
  Rat   969 SITTDAKGQTVLRIT-PDMMATLAK---SQVTTVKLTQDLFGAGSGTAGKGISATLHVTSNPVHA 1029

  Fly  1173 TETASPVTMSTISSPVPGGGTIVKMSPQAFANLQQQQQQLKQKVNNASPALNSPQQRIIVG---- 1233
            .::.:....:::.|..|.|.|:||::|           .||....::|.....|...:.|.
  Rat  1030 ADSPAKAPSASVPSSAPAGTTVVKVTP-----------DLKPTETSSSAFRLMPALGVSVADQKG 1083

  Fly  1234 -NTAISSNKK-----IVFQSLGKAAPKILTT--------------SPSGSVTKATTNLSPQQQRI 1278
             ||..||..|     .:.|.||...||...|              ..||:|..:|.:|
  Rat  1084 KNTVASSEAKPAATIRIVQGLGVMPPKAGQTITVAAHAKQGASVAGGSGTVHSSTVSL------- 1141

  Fly  1279 VLQNFKQPVIATNQSGTLTAVGGNATRVIRATPATSVGTGGIVGAGNPQTAGQIITLDSLLQKQP 1343
                   |.|....|.|: ||...||    :|| .|:|||.
  Rat  1142 -------PSINATVSKTV-AVASGAT----STP-ISIGTGA------------------------ 1169

  Fly  1344 AGGKLLTTAGNNIFQLATSSAGNVITLSPNQTTKQLPTMTRIVSATSTTPATGNASTVVPKIIGK 1408
                                          .|.:|:|..|.:||    |..:|...|       :
  Rat  1170 ------------------------------PTVRQVPVNTTVVS----TSQSGKLPT-------R 1193

  Fly  1409 TTVLPGKPLLLHAKTLKQIGGSSVPTTQTTTTTTTAVASAAVGSG-SGAGGTVVAGT---GATNA 1469
            .||    ||.:.::.:|   |.||        .|..:....:|:. ||.|..::..|   ||...
  Rat  1194 ITV----PLSVISQPMK---GKSV--------VTAPIIKGNLGANLSGLGRNIILTTMPAGAKLI 1243

  Fly  1470 AGR------TTQNIVIGGQTVKLQGAISARGAGAPVQTVIMGNQLLRLASSTSNSGTTSTSGITT 1528
            ||.      |.|.:    |.::.||..:.:   ..:|||...:  |:..:::.:|...||..:||
  Rat  1244 AGNKPVSFLTAQQL----QQLQQQGQATQQ---VRIQTVPASH--LQQGTASGSSKAVSTVVVTT 1299

  Fly  1529 AP 1530
            ||
  Rat  1300 AP 1301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11970	NP_001287243.1	ASXH	<129..219	CDD:290630	26/90 (29%)
		NFRKB_winged	567..669	CDD:291154	29/101 (29%)
Nfrkb	XP_038937300.1	NFRKB_winged	404..490	CDD:405198	24/90 (27%)
		PHA03247	<695..899	CDD:223021	46/210 (22%)
		Herpes_BLLF1	<994..>1200	CDD:282904	66/305 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340999
Domainoid	1	1.000	250	1.000	Domainoid score	I2045
eggNOG	1	0.900	-	-		E1_KOG1927
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	351	1.000	Inparanoid score	I2202
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006911
OrthoInspector	1	1.000	-	-		oto97485
orthoMCL	1	0.900	-	-		OOG6_106779
Panther	1	1.100	-	-	LDO	PTHR13052
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3864
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.840