DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RagA-B and gtr1

DIOPT Version :9

Sequence 1:	NP_649850.1	Gene:	RagA-B / 41071	FlyBaseID:	FBgn0037647	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_595414.1	Gene:	gtr1 / 2540954	PomBaseID:	SPBC337.13c	Length:	308	Species:	Schizosaccharomyces pombe

Alignment Length:	302	Identity:	185/302 - (61%)
Similarity:	240/302 - (79%)	Gaps:	2/302 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKKKVLLMGKSGSGKTSMRSIIFANYIARDTTRLGATIDVEHSHVRFLGNLVLNLWDCGGQEGFM 65
            |:|||||||:|||||:|||||:|:||:|:||.|||||||:||||||||||||||||||||||.||
pombe     1 MRKKVLLMGRSGSGKSSMRSIVFSNYVAKDTRRLGATIDIEHSHVRFLGNLVLNLWDCGGQEAFM 65

  Fly    66 KQYFAQQRDNIFRNVEVLIYVFDVESQEIERDIHYYQSCLEALLQNSPEAKIFCLVHKMDLVPEG 130
            :.|.:.|||:|||||:||||||||||:|.|||:..:::||||.:.|||:|::|||:||||||.|.
pombe    66 ENYLSAQRDHIFRNVQVLIYVFDVESREFERDLVTFRNCLEATVANSPQARVFCLIHKMDLVQED 130

  Fly   131 LRESVFTERMEDLIKLSKPGNVTCFRTSIWDETLYKAWSSIVTMLIPNVAALENSVTHFGNVIEA 195
            ||:.||.||...|::.||....||..||||||||:||||:||..||||...||:.:..|....||
pombe   131 LRDLVFEERKAILLETSKDLETTCLATSIWDETLFKAWSAIVYTLIPNTPTLESHLREFAKAAEA 195

  Fly   196 DEVLLFEKATFLVISHCQSKKN--RDSHRFEKVSNIIKQFKLSCSKLGAKFQSMEVRNSAFAAFI 258
            .||:|||:.||||||...|:.|  .|:|||||:|||:|||||||||:.|:|.:.|:|...|:|||
pombe   196 AEVILFERTTFLVISSYSSESNPATDAHRFEKISNIVKQFKLSCSKMQAQFTTFELRGGNFSAFI 260

  Fly   259 DTFTSNTYVMVVMSDPTLPSEATLVNIRNARKYFEELENPSN 300
            ..:|.:||::||::||.:.|..||:||::||::.|..::.|:
pombe   261 VPYTEDTYILVVIADPEIESAVTLMNIQSARRFIEASKSASD 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RagA-B	NP_649850.1	Gem1	2..>146	CDD:224025	102/143 (71%)
RagA-B	NP_649850.1	RagA_like	4..287	CDD:206744	179/284 (63%)
gtr1	NP_595414.1	RagA_like	4..289	CDD:206744	179/284 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	308	1.000	Domainoid score	I246
eggNOG	1	0.900	-	-		E1_KOG3886
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	383	1.000	Inparanoid score	I415
OMA	1	1.010	-	-		QHG54125
OrthoFinder	1	1.000	-	-		FOG0003768
OrthoInspector	1	1.000	-	-		oto101112
orthoMCL	1	0.900	-	-		OOG6_102718
Panther	1	1.100	-	-	LDO	PTHR11259
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R532
SonicParanoid	1	1.000	-	-		X2625
TreeFam	1	0.960	-	-
	13	12.860