DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RagA-B and Rraga

DIOPT Version :9

Sequence 1:	NP_649850.1	Gene:	RagA-B / 41071	FlyBaseID:	FBgn0037647	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_446425.1	Gene:	Rraga / 117044	RGDID:	619804	Length:	313	Species:	Rattus norvegicus

Alignment Length:	306	Identity:	241/306 - (78%)
Similarity:	267/306 - (87%)	Gaps:	3/306 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKKKVLLMGKSGSGKTSMRSIIFANYIARDTTRLGATIDVEHSHVRFLGNLVLNLWDCGGQEGFM 65
            |||||||||||||||||||||||||||||||.|||||||||||||||||||||||||||||:.||
  Rat     6 MKKKVLLMGKSGSGKTSMRSIIFANYIARDTRRLGATIDVEHSHVRFLGNLVLNLWDCGGQDTFM 70

  Fly    66 KQYFAQQRDNIFRNVEVLIYVFDVESQEIERDIHYYQSCLEALLQNSPEAKIFCLVHKMDLVPEG 130
            :.||..||||||||||||||||||||:|:|:|:|||||||||:|||||:|||||||||||||.|.
  Rat    71 ENYFTSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNSPDAKIFCLVHKMDLVQED 135

  Fly   131 LRESVFTERMEDLIKLSKPGNVTCFRTSIWDETLYKAWSSIVTMLIPNVAALENSVTHFGNVIEA 195
            .|:.:|.||.|||.:||:|....|||||||||||||||||||..|||||..||.::.:|..:|||
  Rat   136 QRDLIFKEREEDLRRLSRPLECACFRTSIWDETLYKAWSSIVYQLIPNVQQLEMNLRNFAQIIEA 200

  Fly   196 DEVLLFEKATFLVISHCQSKKNRDSHRFEKVSNIIKQFKLSCSKLGAKFQSMEVRNSAFAAFIDT 260
            |||||||:||||||||.|.|:.||.|||||:||||||||||||||.|.|||||||||.||||||.
  Rat   201 DEVLLFERATFLVISHYQCKEQRDVHRFEKISNIIKQFKLSCSKLAASFQSMEVRNSNFAAFIDI 265

  Fly   261 FTSNTYVMVVMSDPTLPSEATLVNIRNARKYFEELE---NPSNSAI 303
            ||||||||||||||::||.|||:|||||||:||:||   .|.:|.:
  Rat   266 FTSNTYVMVVMSDPSIPSAATLINIRNARKHFEKLERVDGPKHSLL 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RagA-B	NP_649850.1	Gem1	2..>146	CDD:224025	121/143 (85%)
RagA-B	NP_649850.1	RagA_like	4..287	CDD:206744	227/282 (80%)
Rraga	NP_446425.1	RagA_like	9..292	CDD:206744	227/282 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345354
Domainoid	1	1.000	367	1.000	Domainoid score	I892
eggNOG	1	0.900	-	-		E1_KOG3886
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	483	1.000	Inparanoid score	I1397
OMA	1	1.010	-	-		QHG54125
OrthoDB	1	1.010	-	-		D378768at33208
OrthoFinder	1	1.000	-	-		FOG0003768
OrthoInspector	1	1.000	-	-		otm45294
orthoMCL	1	0.900	-	-		OOG6_102718
Panther	1	1.100	-	-	LDO	PTHR11259
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2625
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.770