DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ich and ADR1

DIOPT Version :9

Sequence 1:	NP_001262393.1	Gene:	ich / 41069	FlyBaseID:	FBgn0286204	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	NP_010502.3	Gene:	ADR1 / 851802	SGDID:	S000002624	Length:	1323	Species:	Saccharomyces cerevisiae

Alignment Length:	162	Identity:	38/162 - (23%)
Similarity:	63/162 - (38%)	Gaps:	31/162 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   439 SGLSLKDNGLCSPDLLGNYPHTTTASTTGSEMRTGAPKAKRSRSQKKS-------------NQQQ 490
            ||..:.|...|..:...|........|..|.:...:..|.|..|...|             |...
Yeast    11 SGFPVVDLNSCFSNGFNNEKQEIEMETDDSPILLMSSSASRENSNTFSVIQRTPDGKIITTNNNM 75

  Fly   491 QQQQQQQQQQGDGGGQPTTPQMSAISPSGFSASDLSGLLGKEKPVHRCSICNRGFLNKSNIKVHL 555
            ..:..:|..:     .|...:::..:|||...|.:            |.:|.|.|..:.::|.|.
Yeast    76 NSKINKQLDK-----LPENLRLNGRTPSGKLRSFV------------CEVCTRAFARQEHLKRHY 123

  Fly   556 RTHTGEKPFRCDVCAKAFRQKAHLLKH-QQIH 586
            |:||.|||:.|.:|.:.|.::..|::| |:||
Yeast   124 RSHTNEKPYPCGLCNRCFTRRDLLIRHAQKIH 155

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ich	NP_001262393.1	C2H2 Zn finger	538..558	CDD:275368	7/19 (37%)
		zf-H2C2_2	550..575	CDD:316026	11/24 (46%)
		C2H2 Zn finger	566..586	CDD:275368	6/20 (30%)
ADR1	NP_010502.3	zf-C2H2	104..126	CDD:395048	7/33 (21%)
		C2H2 Zn finger	106..126	CDD:275368	7/19 (37%)
		zf-H2C2_2	118..143	CDD:404364	11/24 (46%)
		C2H2 Zn finger	134..155	CDD:275368	6/20 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24393
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100