Protein Alignment ich and CG4374

DIOPT Version :10

• Sequence 1: NP_649848.2
• Gene: ich / 41069
• FlyBaseID: FBgn0286204
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_651146.2
• Gene: CG4374 / 42767
• FlyBaseID: FBgn0039078
• Length: 772
• Species: Drosophila melanogaster
• Alignment Length: 673
• Identity: 144/673 - (21%)
• Similarity: 216/673 - (32%)
• Gaps: 234/673 - (34%)

  Fly   117 YMQSAYHPQNQSNPTSTTQSNGGSNSNSNNSNEHNIV--------------------SSSTCLPE 161
            :.|...|.||...|   ..|:.|.|:|:||:|.|..|                    :|:..:.:
  Fly    58 HQQQQQHHQNHQQP---PHSHNGHNNNNNNNNNHVQVVHQPITSQSQQQSLCGGTRTNSNNMIHD 119

  Fly   162 SVLSGSGGGGG-------------GNDACLADVKLFADSQLDSKLYS----------------VA 197
            ....|:|||||             |.|..|...:.:...:.:|:|.|                |.
  Fly   120 GGGGGAGGGGGVVVPVGNRNGTSNGGDPTLQGYEFWHQDKDNSRLDSSSIFEDLDRYCWQQQPVT 184

  Fly   198 DSCVMNGSGS----------------------------------------GSAANGNGSGPSIAT 222
            .|....||.|                                        .|:|..:|:|.|..|
  Fly   185 TSASNGGSASTNQPSPTSPQGHLQQQQQHQQHQQLQQQQQQQQQQQPNANSSSAASSGAGSSSDT 249

  Fly   223 LTPIDQV------------------------------ADSLHNSGVRIYKDLTEYVDMNSIDDIA 257
            ::.:|..                              .|||..|.....|....|.|.....|..
  Fly   250 ISSLDTTDGQIYTLTVLNGGEPWLKRSESEQLPTSLDLDSLLGSFPGYIKSEYPYDDSGFSTDGK 314

  Fly   258 AIIGS---AIADTTVPNQLDKDDNNDTRDSWMDLDAWIDGNCIQQESAKVLVSQQDSLGDF-ILP 318
            .:||:   .::..:.| |........|..|.:...:...||.:.|:.|:.    |::..|: :..
  Fly   315 DVIGNGTDGLSSISQP-QNQGQQAQQTLPSLVTAISLAGGNDLGQQLAQF----QNNNNDWHMAD 374

  Fly   319 HSPLPMHASSSTLQSLL-----SHGY-----------MPL------------------------- 342
            |:   .....||.:|||     ..||           ||:
  Fly   375 HN---TETEQSTAESLLRSALQGKGYAKGLHMQNGLTMPVVKDEDMRRLLFADEAAALGFADSTL 436

  Fly   343 -------------LQNRLQNGPPNGNSSGGGGGAN----------QGAGIKGDPQAPTSTSYCNE 384
                         |.::.|............|.||          :.|......:.....:...:
  Fly   437 SAAQMFDEAQGIHLSSQQQQQQQQQQQQAHNGNANILVDDMFLSLENAFSDDFEKIKRIANEVQQ 501

  Fly   385 LAAATSSSCSPPGSVVSTTDNPNGLMINPRYLSNPTNNQATGNLHQQGGYSMQASGLSLKDNGLC 449
            ..:|.||....||..|.::|..  :.|:|    :|....| |.|........:.|..:
  Fly   502 FCSAGSSGTPTPGDYVPSSDVL--MQISP----SPAVTSA-GQLQPPQPLKPEVSTST------- 552

  Fly   450 SPDLLGNYPHTTTASTTGSEMRTGAPKAKRSRSQKKSNQQQQQQQQQQQQQGDGG---------- 504
            ||      .....||...:.:|:|....|..::.|:|:............|..||
  Fly   553 SP------TSAVVASAASNHVRSGGGVVKPKKAYKRSSSNNNNPNVANNNQSSGGNPLIAGSGSG 611

  Fly   505 -----GQPTTPQMSAISPSGFSASDLSG-LLGKEKPVHRCSICNRGFLNKSNIKVHLRTHTGEKP 563
                 |..::...|..:.||.|:|..|| ...||:.:|.||||.:||.:|.::.||:||||||||
  Fly   612 SSSSSGSASSSSNSPPANSGGSSSSSSGSTQRKERSLHYCSICAKGFKDKYSVNVHIRTHTGEKP 676

  Fly   564 FRCDVCAKAFRQKAHLLKHQQIH 586
            |.|.:|.|:|||||||.||.|.|
  Fly   677 FACSLCGKSFRQKAHLAKHYQTH 699

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ich	NP_649848.2	zf-C2H2	536..558	CDD:395048	11/21 (52%)
		C2H2 Zn finger	538..558	CDD:275368	10/19 (53%)
		zf-H2C2_2	550..575	CDD:463886	15/24 (63%)
		C2H2 Zn finger	566..586	CDD:275368	13/19 (68%)
CG4374	NP_651146.2	zf-C2H2_4	649..671	CDD:464025	11/21 (52%)
		C2H2 Zn finger	651..671	CDD:275370	10/19 (53%)
		zf-H2C2_2	667..688	CDD:463886	14/20 (70%)
		C2H2 Zn finger	679..699	CDD:275370	13/19 (68%)