DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ich and ztf-2

DIOPT Version :9

Sequence 1:	NP_001262393.1	Gene:	ich / 41069	FlyBaseID:	FBgn0286204	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	NP_001379129.1	Gene:	ztf-2 / 184429	WormBaseID:	WBGene00008762	Length:	360	Species:	Caenorhabditis elegans

Alignment Length:	137	Identity:	32/137 - (23%)
Similarity:	56/137 - (40%)	Gaps:	30/137 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   460 TTTASTTGSEMRTGAPKAKRSR------------SQKKSNQQQQQQQQQQQQQGDGGGQPTTPQM 512
            :|..||..|..:....|.:|..            ::|..:|..:::...:|:..:|.......:.
Worm    13 STLLSTLSSPEKEHRRKRRRGEVANPSNTLDALVARKADDQPFEKRYLSEQEAIEGPDDEIEMKK 77

  Fly   513 SAISPSGFSASDLSGLLGKEKPVHRCSICNRGFLNK--SNIKVHLRTHTGEKPFRCDVCAKAFRQ 575
            ..:.|      |:|        ...||.|  |:..|  |.:..|.|.||.|:||:|..|::..:.
Worm    78 MELDP------DVS--------TRTCSTC--GYQGKWVSEMIRHKRVHTSERPFKCRYCSRTSKW 126

  Fly   576 KAHLLKH 582
            ||.|::|
Worm   127 KADLIRH 133

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ich	NP_001262393.1	C2H2 Zn finger	538..558	CDD:275368	8/21 (38%)
		zf-H2C2_2	550..575	CDD:316026	9/24 (38%)
		C2H2 Zn finger	566..586	CDD:275368	6/17 (35%)
ztf-2	NP_001379129.1	C2H2 Zn finger	89..109	CDD:275370	8/21 (38%)
		zf-H2C2_5	115..139	CDD:404746	7/19 (37%)
		C2H2 Zn finger	117..138	CDD:275370	6/17 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5275
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950