DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ScsbetaA and aclyb

DIOPT Version :9

Sequence 1:	NP_001163558.1	Gene:	ScsbetaA / 41067	FlyBaseID:	FBgn0037643	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	XP_001334195.4	Gene:	aclyb / 794259	ZFINID:	ZDB-GENE-090909-2	Length:	1111	Species:	Danio rerio

Alignment Length:	396	Identity:	97/396 - (24%)
Similarity:	160/396 - (40%)	Gaps:	82/396 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 LKTDNLVLKAQVLAGGRGKGTFKNGLKGGVRVVYDPQTAEE-LSSKMIDQLLVTKQTGAAGRICK 138
            |.|:.||:|...|...|||       .|.|.|....::.:| |.|.::.::.|    |.|..:.|
Zfish    50 LLTERLVVKPDQLIKRRGK-------LGLVAVDLKLESVQEWLKSHLMTEITV----GNAKGVLK 103

  Fly   139 KVMVAERKFP---RREFYFAVMMERAFNGPVLIASKEGGVDIEEVAASSPDAILYEPIDIGTGLT 200
            |.:: |...|   ..|||..:...|  .|..::...||||:|.:|...:....|        |:.
Zfish   104 KFLI-EPFVPHIQEEEFYVCIYASR--EGSHVLFHHEGGVEIGDVDNKAQRLTL--------GID 157

  Fly   201 SEQAEKIVKK---VGLGGDGEDTHVQMLLNLYDLFVKKDALLVEINP--YAEDAMSGCFFALDAK 260
            .:..|:||.:   |.:..|.::.....::.|::|:.......:||||  ..:|.:    :.||..
Zfish   158 EKLMEEIVTQQLLVHVPDDKKEVLASFIVGLFNLYEDLYFTYLEINPLVVTKDGV----YVLDMA 218

  Fly   261 LRFDDNAEFRQKEL---------FALRDWTQE----DPKEVEAAKYNLNYIALDGTIGCMVNGAG 312
            .:.|..||:..|..         |....:.:|    |......|...|..:...|.|..||.|.|
Zfish   219 AKIDSAAEYICKPKWGDVEFPPPFGREAYPEEAYIADLDSKSGASLKLTVLNPSGRIWTMVAGGG 283

  Fly   313 LAMATMDIIKLYGG--EPANFLDVGGGATAEAV----KAAFKIIT----SDPKVLCILVNIFGGI 367
            .::...|.|...||  |.||:.:..|..:.:.:    |....::|    ||.|||     |.||.
Zfish   284 ASVVYSDTICDLGGVDELANYGEYSGSPSEQQMYDYAKTILLLMTREKHSDGKVL-----IIGGS 343

  Fly   368 MR--CDVIA--EGIISATKDL-----NLNMPVVVRLQGTKVKEARELIRTSGLKILARDDLDKAA 423
            :.  .:|.|  :||:.|.||.     ...:.:.||..|...:|        ||:::.  ::.|..
Zfish   344 IANFTNVAATFKGIVRAIKDYQEPLKEHEVTIFVRRGGPNYQE--------GLRVMG--EVGKTT 398

  Fly   424 DLAVHL 429
            .:.:|:
Zfish   399 GIPIHV 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ScsbetaA	NP_001163558.1	PLN00124	28..427	CDD:177736	96/392 (24%)
		ATP-grasp_4	39..247	CDD:302634	46/180 (26%)
		Ligase_CoA	307..427	CDD:278948	36/138 (26%)
aclyb	XP_001334195.4	PLN02235	1..419	CDD:177879	97/396 (24%)
		ATP-grasp_4	<55..207	CDD:302634	44/173 (25%)
		Citrate_bind	247..421	CDD:292732	43/173 (25%)
		PLN02522	501..1104	CDD:178137
		NADB_Rossmann	505..610	CDD:304358
		Ligase_CoA	670..795	CDD:304578
		CCL_ACL-C	866..1103	CDD:99854
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0045
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810