DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ScsbetaA and Suclg2

DIOPT Version :9

Sequence 1:	NP_001163558.1	Gene:	ScsbetaA / 41067	FlyBaseID:	FBgn0037643	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_001094220.1	Gene:	Suclg2 / 362404	RGDID:	1305008	Length:	434	Species:	Rattus norvegicus

Alignment Length:	443	Identity:	219/443 - (49%)
Similarity:	289/443 - (65%)	Gaps:	19/443 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAS--FLARTGGPLI--ETVRP--AAIKKILG-LAPIAVQQLRNLNVQEHVSYSLLNEAKIPTPR 58
            |||  .:|...|.|:  .::||  .|::...| |.|     .|.||:||:.|..|::|..:...|
  Rat     1 MASAVAIAAQAGKLLRERSLRPRLLAVRSQAGHLTP-----RRWLNLQEYQSKKLMSEHGVRVQR 60

  Fly    59 FAVAKNGKEANDIATKLKTDNLVLKAQVLAGGRGKGTFKNGLKGGVRVVYDPQTAEELSSKMIDQ 123
            |.||...|||.:.|.:|....:|||||:||||||||.|.:||||||.:..||:...:|:.:||..
  Rat    61 FFVASTAKEAQEAAKRLNAKEIVLKAQILAGGRGKGVFDSGLKGGVHLTKDPKVVGQLAQQMIGY 125

  Fly   124 LLVTKQTGAAGRICKKVMVAERKFPRREFYFAVMMERAFNGPVLIASKEGGVDIEEVAASSPDAI 188
            .|.||||...|....||||||.....||.|.|::|:|:.|||||:.|.:|||||||||||||:.|
  Rat   126 NLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRSHNGPVLVGSPQGGVDIEEVAASSPELI 190

  Fly   189 LYEPIDIGTGLTSEQAEKIVKKVGLGGDGEDTHVQMLLNLYDLFVKKDALLVEINPYAE--DAMS 251
            ..|.|||..|:...||:::.:.:|..|..::.....:..||.||:|.||..||:||:.|  :...
  Rat   191 FKEQIDIFEGIKDSQAQRMAENLGFLGSLKNQAADQIKKLYHLFLKIDATQVEVNPFGETPEGQV 255

  Fly   252 GCFFALDAKLRFDDNAEFRQKELFALRDWTQEDPKEVEAAKYNLNYIALDGTIGCMVNGAGLAMA 316
            .||   |||:.||||||||||::||:.|.::.:|.|.|||:|:|.||.|||.|.|.|||||||||
  Rat   256 VCF---DAKINFDDNAEFRQKDIFAMDDKSENEPIENEAARYDLKYIGLDGNIACFVNGAGLAMA 317

  Fly   317 TMDIIKLYGGEPANFLDVGGGATAEAVKAAFKIITSDPKVLCILVNIFGGIMRCDVIAEGIISAT 381
            |.|||.|.||:||||||:|||.....|..|||::||||||..|||||||||:.|.:||.||..|.
  Rat   318 TCDIIFLNGGKPANFLDLGGGVKESQVYQAFKLLTSDPKVEAILVNIFGGIVNCAIIANGITKAC 382

  Fly   382 KDLNLNMPVVVRLQGTKVKEARELIRTSGLKILARDDLDKAADLAVHLAQIVK 434
            ::|.|.:|:||||:||.|:||:.::::|||.|.:..||:.||..||  |.:.|
  Rat   383 QELELKVPLVVRLEGTNVQEAQNILKSSGLPITSAVDLEDAAKKAV--ASVAK 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ScsbetaA	NP_001163558.1	PLN00124	28..427	CDD:177736	204/400 (51%)
		ATP-grasp_4	39..247	CDD:302634	98/207 (47%)
		Ligase_CoA	307..427	CDD:278948	70/119 (59%)
Suclg2	NP_001094220.1	sucC	41..422	CDD:234813	199/383 (52%)
		ATP-grasp_2	41..249	CDD:285620	98/207 (47%)
		Ligase_CoA	308..422	CDD:278948	68/113 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0045
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60702
OrthoDB	1	1.010	-	-		D342254at33208
OrthoFinder	1	1.000	-	-		FOG0001148
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.830