Protein Alignment pyd and lnx1

DIOPT Version :9

• Sequence 1: NP_001246998.1
• Gene: pyd / 41062
• FlyBaseID: FBgn0262614
• Length: 2395
• Species: Drosophila melanogaster
• Sequence 2: XP_005160562.1
• Gene: lnx1 / 561226
• ZFINID: ZDB-GENE-030131-9439
• Length: 769
• Species: Danio rerio
• Alignment Length: 662
• Identity: 141/662 - (21%)
• Similarity: 233/662 - (35%)
• Gaps: 181/662 - (27%)

  Fly   141 AAAAAEINLANQVYWLGKQKTRSRSRSNSVGNRSITSCMGGGGGGGEKERERGGD----RDRPYI 201
            |..:.|..|.|..|   :......|:|.|..:.:..|       |..|...|..|    |.|.:
Zfish   188 ALLSDEPGLVNPAY---EPSVEDNSQSGSTTSLAARS-------GSRKSEYRNFDRTSVRSRSF- 241

  Fly   202 RNVDDLLQALGKRDGG-----------DN--NSNLLETASTHSSSQRRRFKKGDRTTWEYHTVAV 253
            |.::.....|.:...|           ||  |:|:.......:..|..........|    ::.:
Zfish   242 RRLNRAFSVLRRTKSGTAVANDTTEERDNLRNANIPAEGELFALPQLHHLIPDGEVT----SIKI 302

  Fly   254 TRV-PGYGFGIAVSGGRDNPHFANGDPSIAVSDVLKGG--PAEDRLQVNDRIISVNGVSLENVEY 315
            ||. |.....|::.||.:.|..     .|.:.|:.:.|  ..:.||...|.|:.|||:.:.||.:
Zfish   303 TRADPCEPLAISIVGGNETPLV-----RILIQDIYREGVIARDGRLLPGDMILKVNGIDISNVPH 362

  Fly   316 ATAVQVLRDSGNTVQLVVKRRVPLNPINAAGAVQHQ---HSHSLSSVGLMANGSGGVAPTPI--- 374
            ..||..|:.....::|.|.|.           .:|:   |.||               ||..
Zfish   363 CYAVAALKQPCTLLRLTVLRE-----------QRHRYRSHHHS---------------PTEAFPA 401

  Fly   375 -TSLSQPNSLNSSLVQNASSGQPIKVTLTKGGKKDDYGVVLGCRLFVKEISSKARE--------Q 430
             |:..:.:||:..||:.|...| :.:.|.:  :.|::||.:   ..:.|....||:        .
Zfish   402 HTATIRDDSLHVVLVKRAPDEQ-LGIKLVR--RPDEHGVFI---FHLLEGGLAARDGRLRVDDRV 460

  Fly   431 LNANGYSLQEGDIITRIHNTNCGDTMSLKEAKKIIDGCKERLNLVVLRDITNQTAVSQLNLNNSA 495
            |..||:.|:.|               :.:.|..:|...::|::.:|.|    ||.:...::...|
Zfish   461 LAINGHDLRYG---------------APEHAALLIQASEDRVHFIVSR----QTHIPAPDILQEA 506

  Fly   496 SHQASGNIYATHQP-----------QVSGC-SSSNNNLEDPY------LPGGASYSSQNLYVQPP 542
            .....|.  ..:.|           |...| ..:...|::|:      :.||.|....:|.|...
Zfish   507 PWNMEGP--PPYSPVDIEHTLLDSCQKPACYEKTVTLLKEPHDSLGMTVAGGMSSRGWDLPVYVT 569

  Fly   543 TRTSNGP--------------NINGNGL-----NDEKSNLTPRGRSRGPIMDGVSLQQLD-RP-- 585
            ....||.              |:||..|     ::..:||.   .:..|::    ||.|: ||
Zfish   570 NVDPNGVVGQEGSIRKGDILLNVNGVDLTGVTRSEAVANLK---NTSSPVV----LQVLEMRPPN 627

  Fly   586 ------VTPTRGRSAAIDEPP---RPPPPRGSSGGAAQEDF---YSSRRQLYEERQSAEPRFISF 638
                  :.|.....|.....|   :.|||        .:|:   :.|..||.......:...:..
Zfish   628 ESSLDCMPPLHSPCALSPSSPGDVKLPPP--------NDDYAPLWVSWLQLPRHLYCCKDIVLRR 684

  Fly   639 QKEGSVGIRLTGGNE-----AGIFVTAVQPGSPASLQG-LMPGDKILKVNDMDMNGVTREEAVLF 697
            ...||:|..:.||.|     ...|:.::..|:||...| :..||.:|:||.....|:|....|..
Zfish   685 STSGSLGFSIVGGQEELNCNQSFFIRSIVEGTPAYNDGRIRCGDILLEVNGKSTWGMTHTALVRL 749

  Fly   698 LLSLQDRIDLIV 709
            |..|:.||.|.:
Zfish   750 LKELRGRITLTI 761

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pyd	NP_001246998.1	PDZ_signaling	249..334	CDD:238492	23/87 (26%)
		PDZ_signaling	396..477	CDD:238492	15/88 (17%)
		PDZ_signaling	633..710	CDD:238492	24/83 (29%)
		SH3_ZO	729..790	CDD:212793
		GuKc	831..1007	CDD:214504
		ZU5	2263..2351	CDD:279170
lnx1	XP_005160562.1	RING	57..93	CDD:214546
		PDZ_signaling	297..381	CDD:238492	24/92 (26%)
		PDZ_signaling	411..491	CDD:238492	20/100 (20%)
		PDZ_signaling	536..621	CDD:238492	18/91 (20%)
		DegQ	<548..621	CDD:223343	16/79 (20%)
		PDZ_signaling	678..762	CDD:238492	24/84 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910