DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pyd and slc9a3r1

DIOPT Version :9

Sequence 1:	NP_001246998.1	Gene:	pyd / 41062	FlyBaseID:	FBgn0262614	Length:	2395	Species:	Drosophila melanogaster
Sequence 2:	NP_001006751.1	Gene:	slc9a3r1 / 448423	XenbaseID:	XB-GENE-487362	Length:	320	Species:	Xenopus tropicalis

Alignment Length:	175	Identity:	46/175 - (26%)
Similarity:	76/175 - (43%)	Gaps:	29/175 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   559 EKSNLTPRGRSRGPIMDGVSLQQLDRPVTPTRGRSA---------AIDEPPRPPPPRGSSGGAAQ 614
            ||:.|  |...|...:.|..:::|......::.|:|         .::|...|..|:
Frog    41 EKAGL--RAGDRLIRVCGEDVRELGHQQVVSKIRAATEKLTLEVQGVEEEVAPSSPK-------- 95

  Fly   615 EDFYSSRRQLYE--ERQSAEPRFISFQKEGS-VGIRLTGGN-EAGIFVTAVQPGSPASLQGLMPG 675
            |:..::.:|...  :|:...||..:.:|..| .|..|.... ..|.||.||.|.|||.|.||:|.
Frog    96 EENKATEKQPTPVLDRKELRPRLCTIKKGPSGFGFNLHSDKVHPGQFVRAVDPDSPAELAGLLPK 160

  Fly   676 DKILKVNDMDMNGVTREEAVLFLLSLQDRIDLIV------QYCKE 714
            |:|::||.:::.|....:.|..:.:..|...|:|      .|.||
Frog   161 DRIVEVNGLNVIGKQHGDVVAAIKAGGDETSLLVLDPEADSYFKE 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pyd	NP_001246998.1	PDZ_signaling	249..334	CDD:238492
		PDZ_signaling	396..477	CDD:238492
		PDZ_signaling	633..710	CDD:238492	28/84 (33%)
		SH3_ZO	729..790	CDD:212793
		GuKc	831..1007	CDD:214504
		ZU5	2263..2351	CDD:279170
slc9a3r1	NP_001006751.1	PDZ_signaling	4..83	CDD:238492	9/43 (21%)
		PDZ_signaling	116..195	CDD:238492	27/78 (35%)
		EBP50_C	199..320	CDD:370238	3/7 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910