DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pyd and sdcbp

DIOPT Version :9

Sequence 1:	NP_001246998.1	Gene:	pyd / 41062	FlyBaseID:	FBgn0262614	Length:	2395	Species:	Drosophila melanogaster
Sequence 2:	NP_999963.2	Gene:	sdcbp / 407719	ZFINID:	ZDB-GENE-081104-57	Length:	307	Species:	Danio rerio

Alignment Length:	260	Identity:	58/260 - (22%)
Similarity:	96/260 - (36%)	Gaps:	49/260 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   516 SSNNNLEDPYLPGGASYSSQNLYVQPPTRTSNGPNINGNGLNDEKSNLTPRGRSRGPIMDGVSLQ 580
            ||:.|....|....|..:..:..:.|......|.|::.:.|....|::.  .::.|.:.
Zfish    36 SSDQNEPSTYYDSKAEQTGTSSRLYPELNEFMGLNLSSDALQTFSSSIA--DQTAGALS------ 92

  Fly   581 QLDRPVTPTRGRSAAIDEPPRPPPPRGSSGGAAQEDFYSSRRQLYEERQSAEPRFISFQKEGSVG 645
                  ..|.|.|.|      ..|..||..|..:.          |.||......:....:|.:|
Zfish    93 ------VCTSGMSWA------AAPITGSDLGVKRA----------EIRQGVREVVLCKDMDGKIG 135

  Fly   646 IRLTGGNEAGIFVTAVQPGSPASLQGLMPGDKILKVNDMDMNGVTREEAVLFLL-SLQDRIDLIV 709
            :||. ..:.|:||..||..:.|:|.||..||:||::|.....|...:.|...|. |..:||.|.|
Zfish   136 LRLK-AIDNGVFVQLVQANTAAALAGLRFGDQILEINGKSCAGWNSDYAHKVLKNSNPERITLAV 199

  Fly   710 QYCKEEYDEVVTNQRGDSFHIKTHFHCDNPSKGEMAFKAGDVFRVI---DTLHNGVVGSWQVLKI 771
            :  ....:..||            .|.|...:....|:.|.:..::   .:..||::...|:.:|
Zfish   200 R--DRPLERTVT------------LHKDMNGQLGFIFRKGRITSIVKDSSSARNGLLTDHQICEI 250

Fly 772 771
Zfish 251 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pyd	NP_001246998.1	PDZ_signaling	249..334	CDD:238492
		PDZ_signaling	396..477	CDD:238492
		PDZ_signaling	633..710	CDD:238492	25/77 (32%)
		SH3_ZO	729..790	CDD:212793	8/46 (17%)
		GuKc	831..1007	CDD:214504
		ZU5	2263..2351	CDD:279170
sdcbp	NP_999963.2	PDZ_signaling	121..200	CDD:238492	25/79 (32%)
sdcbp	NP_999963.2	PDZ_signaling	205..278	CDD:238492	10/58 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910