DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pyd and sdcbp2

DIOPT Version :9

Sequence 1:	NP_001246998.1	Gene:	pyd / 41062	FlyBaseID:	FBgn0262614	Length:	2395	Species:	Drosophila melanogaster
Sequence 2:	NP_997856.1	Gene:	sdcbp2 / 325004	ZFINID:	ZDB-GENE-030131-3727	Length:	299	Species:	Danio rerio

Alignment Length:	275	Identity:	65/275 - (23%)
Similarity:	110/275 - (40%)	Gaps:	62/275 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   508 QPQVSGCSSSNNNLEDPYLPGGASYSSQNLYVQPPTRTSNGPNINGNGLNDEKSNLTPRGRSRGP 572
            |.|.:..:||.     |.:..||        .||...|...|:          |.|.|.....|.
Zfish    19 QSQFANATSST-----PAITQGA--------YQPQPATQGMPS----------STLYPNLEELGD 60

  Fly   573 IMDGVSL--QQLDR-----PVTPTRGRSAAIDEPPRPPPPRGSSGGAAQEDFYSSRRQLYEERQS 630
            .| |:||  .::.|     ||.......:::....|  |..|:..|..:.:.....|::
Zfish    61 YM-GLSLNSDEVQRNLALVPVATQVAVPSSVGGMVR--PVTGADMGIRRAEIRPGLREV------ 116

  Fly   631 AEPRFISFQKEGSVGIRLTGGNEAGIFVTAVQPGSPASLQGLMPGDKILKVNDMDMNGVTREEAV 695
                .:...:||.||:||. ..:.|:||..||..|||:|.||..||::|::|..::.|...::|.
Zfish   117 ----ILCKDQEGKVGLRLR-DIDNGVFVQLVQANSPAALAGLRFGDQVLQINGQNVAGWNSDKAH 176

  Fly   696 LFL-LSLQDRIDLIVQYCKEEYDEVVTNQRGDSFHIKTHFHCDNPSKGEMAFKAGDVFRVI---D 756
            ..| .:.:.||:|||:  ...:...:|..:..|.|:            ...||:|.:..::   .
Zfish   177 KALKAAAEQRIELIVR--DRPFQRTITMHKDSSGHV------------GFIFKSGRITSLVKDGS 227

  Fly   757 TLHNGVVGSWQVLKI 771
            ...||::....:.:|
Zfish   228 AARNGLLTEHYICEI 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pyd	NP_001246998.1	PDZ_signaling	249..334	CDD:238492
		PDZ_signaling	396..477	CDD:238492
		PDZ_signaling	633..710	CDD:238492	28/77 (36%)
		SH3_ZO	729..790	CDD:212793	7/46 (15%)
		GuKc	831..1007	CDD:214504
		ZU5	2263..2351	CDD:279170
sdcbp2	NP_997856.1	PDZ_signaling	113..>173	CDD:238492	23/70 (33%)
sdcbp2	NP_997856.1	PDZ_signaling	198..270	CDD:238492	9/57 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910