DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pyd and mics-1

DIOPT Version :9

Sequence 1:	NP_001246998.1	Gene:	pyd / 41062	FlyBaseID:	FBgn0262614	Length:	2395	Species:	Drosophila melanogaster
Sequence 2:	NP_001343863.1	Gene:	mics-1 / 179475	WormBaseID:	WBGene00011890	Length:	293	Species:	Caenorhabditis elegans

Alignment Length:	208	Identity:	49/208 - (23%)
Similarity:	79/208 - (37%)	Gaps:	37/208 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   250 TVAVTRVPGYGFGIAVSGGRDNPHFANGDPSIAVSDVLKGGPAEDRLQVNDRIISVNGVSLENVE 314
            ||........|||..:.||.|||||. ||..|.||.|.....:...::..|:|:|.:|:.:....
Worm    72 TVVEIEKTSKGFGFNIVGGTDNPHFV-GDIGIYVSSVNSESKSYGVVRTGDKILSFDGIDMTYKT 135

  Fly   315 YATAVQVLRD--SGNTVQLVVKRRVPLNPINAAGAVQHQHSHSLSSVGLMANGSGGVAP--TPIT 375
            :..||:|.|.  .|:..::::.|               ::.|...........|..:.|  ||.|
Worm   136 HDEAVEVFRSVKIGHVAKMLIDR---------------EYLHLQEDRTQTPTASVSITPQVTPQT 185

  Fly   376 SLSQPNSLNSSLVQNASSGQPIKVTLTKGGKKDDYGVVLGCRLFVKEISSKAREQLNA---NGYS 437
            ..:|.|:.....:.::.|    |..||..          |....::.|..|..|:.:|   ..|:
Worm   186 RSTQNNTDTPKSMSHSES----KSRLTSH----------GLSAVIERIRGKVYEEEDAQSVTSYA 236

  Fly   438 LQEGDIITRIHNT 450
            .....||..:..|
Worm   237 PSTHSIIDDVPRT 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pyd	NP_001246998.1	PDZ_signaling	249..334	CDD:238492	27/85 (32%)
		PDZ_signaling	396..477	CDD:238492	12/58 (21%)
		PDZ_signaling	633..710	CDD:238492
		SH3_ZO	729..790	CDD:212793
		GuKc	831..1007	CDD:214504
		ZU5	2263..2351	CDD:279170
mics-1	NP_001343863.1	PDZ_signaling	71..145	CDD:238492	25/73 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910