DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pyd and LOC100537443

DIOPT Version :9

Sequence 1:	NP_001246998.1	Gene:	pyd / 41062	FlyBaseID:	FBgn0262614	Length:	2395	Species:	Drosophila melanogaster
Sequence 2:	XP_003199722.2	Gene:	LOC100537443 / 100537443	-ID:	-	Length:	201	Species:	Danio rerio

Alignment Length:	200	Identity:	49/200 - (24%)
Similarity:	100/200 - (50%)	Gaps:	22/200 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   836 VFSDSISKFPAYERVVLRHPGFVRPVVLFGPVSDLARERLAKDFPDKFSTPLQDDDKS------- 893
            |..|.:|  |||:||:.......|||::.||:.:..::.|.::.|.|:...|.:..|:
Zfish     1 VLPDCVS--PAYQRVLKVESTNRRPVLILGPLVEPIKDMLLREAPGKYCRCLPEGMKAQQQAIER 63

  Fly   894 ----------AATSGKCRIVRLSNIRDVMDRGKHALLDITPNAVDRLNYAQFYPVVIFLKTDSKH 948
                      ...||...:..:::|:::.::..|.||||.|:|::||:....||:|||::..:..
Zfish    64 GVKDCLFIDYKRRSGHFDVTTVASIKEITEKDCHCLLDIAPHAIERLHAVSIYPIVIFIRYRNAK 128

  Fly   949 VIKQLRHGL---PKAAHKSSKKLLEQCQKLERVWSHIFSTQIALSDEESWYRKLRDSIDLQQSGA 1010
            .||:.:..:   .|.:.|.||:..|..|::|:.:|..|:..:......:...::...:|.:|:..
Zfish   129 QIKEQKDPVYLRDKVSQKHSKEQFESAQRIEQDYSKYFTGVVQAGALSNTCTQIMAIVDQEQNKV 193

  Fly  1011 VWMSE 1015
            :|:.:
Zfish   194 LWIPD 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pyd	NP_001246998.1	PDZ_signaling	249..334	CDD:238492
		PDZ_signaling	396..477	CDD:238492
		PDZ_signaling	633..710	CDD:238492
		SH3_ZO	729..790	CDD:212793
		GuKc	831..1007	CDD:214504	47/190 (25%)
		ZU5	2263..2351	CDD:279170
LOC100537443	XP_003199722.2	NK	34..190	CDD:327404	34/155 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910