Protein Alignment pyd and pdzrn3

DIOPT Version :9

• Sequence 1: NP_001246998.1
• Gene: pyd / 41062
• FlyBaseID: FBgn0262614
• Length: 2395
• Species: Drosophila melanogaster
• Sequence 2: XP_002938429.1
• Gene: pdzrn3 / 100496746
• XenbaseID: XB-GENE-5817964
• Length: 1062
• Species: Xenopus tropicalis
• Alignment Length: 977
• Identity: 182/977 - (18%)
• Similarity: 300/977 - (30%)
• Gaps: 378/977 - (38%)

  Fly   200 YIRNVDDLLQALGKRDGGDNNSNLLETASTHSSSQRRRFKKGDRTTWEYHTVAVTRVPGYGFGIA 264
            |...:|.|.:|:.....|:.:..:                          |:.:.|..| ..|..
 Frog   222 YSTRLDSLTKAVASPGKGEESKAM--------------------------TLVLHRESG-SLGFN 259

  Fly   265 VSGGRDNPHFANGDPS--IAVSDVLKGGPA--EDRLQVNDRIISVNGVSLENVEYATAVQVLRDS 325
            :.|||......:|..|  |.||.::..|||  |..||::||||.|||..|....:..||:..:.:
 Frog   260 IIGGRSCVDNQDGPSSEGIYVSKIVDSGPAAKEGGLQIHDRIIEVNGKDLSRATHDQAVEAFKTA 324

  Fly   326 GNTVQLVVKRRVPLNPINAAGAVQHQHSHSLSSVGLMANGSGGVAPTPITSLSQPNSLNSSLVQN 390
            ...:.:.|.||                                   ||.|.:..|
 Frog   325 KEPIVVQVLRR-----------------------------------TPRTKVFSP---------- 344

  Fly   391 ASSGQPIKVTLTKGGKKDDYGVVLGCRLFVKEISSKAREQLNANGYSLQEGDIITRIHNTNCGDT 455
                 |..|.|.
 Frog   345 -----PADVQLL----------------------------------------------------- 351

  Fly   456 MSLKEAKKIIDGCKERLNLVVLRDITNQTAVSQLNLNNSASHQASGNIYATHQPQVSGCSSSNNN 520
                                   |:..||.:       :..|.|:.....:..|.|:|.
 Frog   352 -----------------------DMGTQTEI-------TFEHIAALTKIGSPSPSVAGL------ 380

  Fly   521 LEDPYLPGGASYSSQNLYVQPPTRTSNGPNINGNGLNDEKSNLTPRGRSRGPIMDGVSLQQLDRP 585
              ||||     .:.::    .|......||....||:.|...            |.:.|:::|
 Frog   381 --DPYL-----LTEEH----SPAHDYFDPNDFMGGLHPEMDR------------DELELEEID-- 420

  Fly   586 VTPTRGRSAAIDEPPRPPPPRGSSGGAAQEDFYSSRRQLYEERQSAEPRFISFQKEG-SVGIRLT 649
                                                  ||        |..|..|.| :|..|..
 Frog   421 --------------------------------------LY--------RMNSQDKLGLTVCYRTD 439

  Fly   650 GGNEAGIFVTAVQPGSPASLQG-LMPGDKILKVNDMDMNGVTREEAVLFLLSLQDR-IDLIVQYC 712
            ..::.||:|:.:.|.|.|:..| :..||:|:::|.:|:|  ..||||..|.|...: :.|:|...
 Frog   440 DEDDTGIYVSEIDPNSIAAKDGRIREGDRIIQINGIDVN--NHEEAVALLTSEDTKNVFLLVARP 502

  Fly   713 KEEYDE-VVTNQRGDSFHIKTHFHCDNPSKGEMAFKAGDVFRVIDTLHNGVVGSWQVLKIGRGHQ 776
            :.:.|| .:.:.|.|                           .:|.||..::..       :.||
 Frog   503 ELQLDEGWMDDDRND---------------------------FLDDLHMDMLEE-------QHHQ 533

  Fly   777 EMQ--RGVIPNKSRAE-----ELATAQFNATKKEMNANESRGNFFRRRRSTHRRSKSLSRENW-D 833
            .||  ..::..|...|     :.||...|..:|:....       |...|| |..:|..:||. |
 Frog   534 AMQFTASMLQQKKLEEDGGTTDTATLLSNHLEKDSGVG-------RTDEST-RNDESSEQENLAD 590

  Fly   834 DVVFSDSISKFPAYERVVLRHPGFVRPVVLFGPVSDLARERLAKDFPDKFSTPLQDDDK-SAATS 897
            |  .:.|.:...::::::..........:.|...|.::.:....||   ...|:.:.:: .....
 Frog   591 D--HTTSSNTLGSHKKLMYSQDTLGSGDMQFSNESFISADCTDADF---LGIPMDECERFRELLE 650

  Fly   898 GKCRIVRLSNIRDVMDRGKHALLDITPNAVDRLNYAQFYPVVIFLKTDSKHVIKQLRHGLPKAAH 962
            .||: |:.||     .|.::     ..|:....|           ::|.:.|.::|.. |.:..|
 Frog   651 LKCQ-VQSSN-----QRSRY-----YQNSTMETN-----------RSDQESVDRELEM-LNEELH 692

  Fly   963 KSSKKLLE--QCQKLERVWSHIFSTQIALSDE--ESW------YRKLRDSIDLQQSGAVWMSESK 1017
            ....:.|.  :..|:::           |.|:  |||      :|....||||::
 Frog   693 SIELECLNIVRAHKMQQ-----------LKDQYRESWMLHNSGFRNYNTSIDLRR---------- 736

  Fly  1018 PVESLSDDFLFPMTTSRLSYAS--------SPESDLELSPGPSAS--LSLGNLPQLVKASSDPSI 1072
              ..|||....|..:.:.|.::        |....||:||..|..  ..:.|.|....|:.....
 Frog   737 --HELSDITELPEKSDKDSSSAYNTGESCRSTPLTLEISPDNSLRRVADVINCPNAEGAAGSAPC 799

  Fly  1073 ATNQDNLDRDRDIIGEGLPPPYTVPY---DHAVPANPNRRQTMDSSKY-----SIYGTNVPPQQQ 1129
            :..|.||....| ..|..|..|.:|.   |.:..|....|:|.|:.|.     .:.|:..||.:.
 Frog   800 SAPQKNLQTHGD-SRESSPARYHLPLKDTDPSKQAENKERKTSDAGKSQTSQDKLSGSYAPPYRH 863

  Fly  1130 QP 1131
            .|
 Frog   864 SP 865

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pyd	NP_001246998.1	PDZ_signaling	249..334	CDD:238492	28/88 (32%)
		PDZ_signaling	396..477	CDD:238492	3/80 (4%)
		PDZ_signaling	633..710	CDD:238492	26/79 (33%)
		SH3_ZO	729..790	CDD:212793	8/62 (13%)
		GuKc	831..1007	CDD:214504	34/187 (18%)
		ZU5	2263..2351	CDD:279170
pdzrn3	XP_002938429.1	RING	18..54	CDD:214546
		PDZ	246..335	CDD:214570	29/89 (33%)
		PDZ_signaling	418..487	CDD:238492	26/118 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910