Protein Alignment pyd and sntb2

DIOPT Version :9

• Sequence 1: NP_001246998.1
• Gene: pyd / 41062
• FlyBaseID: FBgn0262614
• Length: 2395
• Species: Drosophila melanogaster
• Sequence 2: XP_002666958.1
• Gene: sntb2 / 100331323
• ZFINID: ZDB-GENE-131121-511
• Length: 519
• Species: Danio rerio
• Alignment Length: 541
• Identity: 111/541 - (20%)
• Similarity: 185/541 - (34%)
• Gaps: 147/541 - (27%)

  Fly   189 ERERGGDRDRP----YIRNVDDLLQALGKRDGGDNNSNLLETASTHSSSQRRRFKKG-DRTTWEY 248
            |.|.||....|    :::|        |..:|.:.|.::......:.:|..|....| |..:..|
Zfish    39 EGEPGGPAGYPEHNSHLKN--------GVSNGNEQNRDVFTNRVQYDNSPGRVNGTGSDSESSGY 95

  Fly   249 ------HTVAVTRVPGYGFGIAVSGGRDN--PHFANGDPSIAVSDVLKGGPAED--RLQVNDRII 303
                  ..|.:.:....|.||::.|||:|  |        |.:|.:..|..|:.  .|:|.|.|:
Zfish    96 CDSEGVRRVRIVKQESGGLGISIKGGRENRMP--------ILISKIFPGLAADQSRALRVGDAIL 152

  Fly   304 SVNGVSLENVEYATAVQVLRDSGNTVQLVVKRRVPLNPINAAGAVQHQHSHSLSSVG-LMANGSG 367
            ||||..|.:..:..|||.|:.:|..|.|.||....::|:....::    |..||..| |.:....
Zfish   153 SVNGSDLRDATHDAAVQALKKAGKEVTLEVKYIREVSPLFKKSSM----SADLSWDGRLQSPNLS 213

  Fly   368 GVAPTPITSLSQPNSL----NSSLVQNASSGQPIKVTLTKGGKKDDYGVVLGCRLFVKEISSKAR 428
            ....:|.:|:|:...:    .|.:.:|.:...|....|........:.|||.|           :
Zfish   214 SSDESPKSSVSRDRKVIPLKMSFISRNLTMPDPENRLLELHSPDGQHTVVLRC-----------K 267

  Fly   429 EQLNANGYSLQEGDIITRIH---------------------NTNCGDTMSLKEAKKII-----DG 467
            :...|:.:       .|.||                     ||:|    :||....::     ||
Zfish   268 DGATAHSW-------FTAIHTNVAALLPQTLSYINTFLNNANTHC----TLKHIGWLVEQLDMDG 321

  Fly   468 CKERLNLVVL----RDITNQTAVSQLNLNNSASHQASGNIYATHQPQVSGCSSSNNNLEDPYLPG 528
            .:.:...|::    :||....||..       ::::......||....:....|.:....|.|.|
Zfish   322 SRHQYKRVIMALTEKDILLFQAVPW-------TYESWTTPVLTHPLLATRLVHSGSVRSSPALGG 379

  Fly   529 GASYSSQNLYVQPPTRTSNGPNINGN--------GLNDEKSNLTPRGRSRGPIMDGVS------- 578
            ...::         |||..|..|..:        .|:.....|...|.|...::..||
Zfish   380 DLLFA---------TRTGTGRGIESHVFRVETHWDLSTWTRALVQGGHSAAELIKEVSIGCVLNR 435

  Fly   579 -----LQQLDRPVTPTRGRSAAIDEPPRPPPPRGSSGGAAQEDFYSSRRQLYEERQSAEPRFISF 638
                 :...:|..|.||                 .||.:....|...|.::..: ......|:.|
Zfish   436 QNVRLILHYERGFTVTR-----------------ESGDSVLFHFPYERLKMSAD-DGVRNLFLDF 482

  Fly   639 -QKEGSVGIRLTGGNEAGIFV 658
             ..||.:...|..|.:..:||
Zfish   483 GAPEGEMVFELHSGPKPVVFV 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pyd	NP_001246998.1	PDZ_signaling	249..334	CDD:238492	29/88 (33%)
		PDZ_signaling	396..477	CDD:238492	18/106 (17%)
		PDZ_signaling	633..710	CDD:238492	8/27 (30%)
		SH3_ZO	729..790	CDD:212793
		GuKc	831..1007	CDD:214504
		ZU5	2263..2351	CDD:279170
sntb2	XP_002666958.1	PDZ_signaling	101..183	CDD:238492	29/89 (33%)
		PHsplit_syntrophin	<228..285	CDD:269960	12/74 (16%)
		PH	307..415	CDD:278594	22/123 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910