Protein Alignment pyd and magi2b

DIOPT Version :9

• Sequence 1: NP_001246998.1
• Gene: pyd / 41062
• FlyBaseID: FBgn0262614
• Length: 2395
• Species: Drosophila melanogaster
• Sequence 2: XP_021326360.1
• Gene: magi2b / 100001810
• ZFINID: ZDB-GENE-141211-6
• Length: 1171
• Species: Danio rerio
• Alignment Length: 1045
• Identity: 210/1045 - (20%)
• Similarity: 361/1045 - (34%)
• Gaps: 338/1045 - (32%)

  Fly   260 GFGIAVSGGRDNPHFANGDPSIAVSDVLKGGPA--EDRLQVNDRIISVNGVSLENVEYATAVQVL 322
            |||..:.|| |.|     |..:.|..|:..|||  :.::...|.|:.:|.:.:....:|..|::.
Zfish   275 GFGFTIIGG-DEP-----DEFLQVKSVIPEGPAAQDSKMDTGDVIVYINDICVLGTTHADVVKLF 333

  Fly   323 RD--SGNTVQLVVKRRVPL----------NPINAAGAVQH-----------QHSHSLSSVGLMAN 364
            :.  .|.:|.||:.|..||          :.:...|.|.|           .:...:|..|.:..
Zfish   334 QSVPIGQSVTLVLCRGYPLPYDPEDPSASSSMPPLGLVDHPLLLNGRNNYENYMEYMSLTGRLVP 398

  Fly   365 GSG-GVAPTP---ITSL--SQPNSL-------NSSLVQNASSG---------QPIKVTLTKGGKK 407
            ..| |:.|.|   .|.|  |||.||       :.|:...:|||         :.:.:|:|||.:.
Zfish   399 EHGEGLTPLPHPGDTHLDGSQPPSLTTPGPPPDDSVSMASSSGATAGATVAPELLSLTITKGAEG 463

  Fly   408 DDYGVVLGCRLFVKEISSKAREQLNANGY-SLQEGDIITRIHNTNCGDTMSLKEAKKIIDGCK-- 469
                  .|..:.......:.::.|...|. .|.|||:|..| |..|...::..:..:::..|.
Zfish   464 ------FGFTIADSPTGQRVKQVLEPQGCPGLCEGDLIVEI-NQKCLQGLNHTQVVQLLKDCPVG 521

  Fly   470 ERLNLVVLRDITNQTAVSQLNLNNSASHQASGNIYATHQPQVSGCSSSNNNLEDPYLPGGASYSS 534
            ....||:.|..|..|......|.:....|.|        || :|.|::       .||.||.:.:
Zfish   522 TEATLVIQRGTTFSTWKEGRTLKDRWDPQGS--------PQ-TGLSAT-------LLPHGAPHPA 570

  Fly   535 QNLYVQPPTRTSNGPNINGNGLNDEKSNLTPRGRSRGPIMDGVSLQQLDRPVTPTRGRSAAIDEP 599
            |.|:                             ||..|..:...|
Zfish   571 QTLH-----------------------------RSSVPDSEAFHL-------------------- 586

  Fly   600 PRPPPPRGSSGGAAQEDFYSSRRQLYEERQSAEPRFIS--------------FQKEGSVGIRLTG 650
            .:|.|          .|.|...|.:||.||...||.::              .:::...|.|:.|
Zfish   587 GKPDP----------YDLYEKSRAIYESRQPLPPRTLTDSTGVEYQEVEVHLLREKTGFGFRILG 641

  Fly   651 GNEA--GIFVTAVQPGSPASLQG-LMPGDKILKVNDMDMNGVTREEAVLFLLSLQDRIDLIVQYC 712
            |:||  .|.:.|:...|||...| |.|||:::.|:.|.:.|
Zfish   642 GDEAVQAIVIGAIIENSPAERDGRLRPGDELVSVDRMPVGG------------------------ 682

  Fly   713 KEEYDEVVTNQRGDSFHIKTHFHCDNPSKGEMAFKAGDVFRVIDTLHNGVVGSWQVLKIGRGHQE 777
                              :.|.:                  |||.:|       ...:.|:....
Zfish   683 ------------------RPHRY------------------VIDLMH-------AAARNGQVTLT 704

  Fly   778 MQRGVIPNKSR--AEELATAQFNATKK-----EMNANESRGNFFRRRRSTHRRSKSLSRENWDDV 835
            ::|.|:..:|:  .|...:|..|::.:     .:|...:......|:.|          |.:..|
Zfish   705 VRRRVLTQQSQPCEENGGSANQNSSPRGHAVCPVNLPPTTDVVIHRKES----------EGFGFV 759

  Fly   836 VFSDSISKFPAYERVVLRHPGFVRPVVLFGPVSDLARERLAKDFPDKFSTPLQDDDKSAATSGKC 900
            :.| |:::......:.:.|.  :..::...|.     :|..|         |:..|:..|.:  |
Zfish   760 IIS-SLNRPETTNTITVPHK--IGRIIEGSPA-----DRCGK---------LKVGDRIMAVN--C 805

  Fly   901 R-IVRLSN---IRDVMDRGKHALLDITPNAVDRLNYAQFYPV------VIFLK----TDSKHVIK 951
            : |:.:.:   ::.:.|.|....|.|.|.  :.:|.|...|.      ::..|    |.|....:
Zfish   806 QSIINMPHADIVKLIKDAGLTVTLHIIPE--EDVNGAHSAPTSEKQSPMVAQKHSPQTQSSPATQ 868

  Fly   952 Q---LRHGLPKAAHKS------SKKLLEQCQKLERVWSHIFSTQIALSDEESWYRKLRDSIDLQQ 1007
            |   :.|..|.|.|.|      |..|::|..........:....:::|         :..::..|
Zfish   869 QSPTMAHPSPPAPHPSPATTQPSPLLVDQSPGAPHGSPPLTQGSVSVS---------QAGLESMQ 924

  Fly  1008 SGAVWMSESKPVESLSDDFLFP-MTTSRLSYASSPESDLELSPGPSASLSLGNLPQLVKASSD-- 1069
            :|:. |:::.||       |.| ||..:.:...|..     .|.|| .|.|.:....|||..|
Zfish   925 TGSA-MTQAAPV-------LDPGMTGIQTTIIGSVP-----VPVPS-QLYLHDTRSEVKARQDVK 975

  Fly  1070 PSIAT------NQDNLDRDRDIIGEGLPPPYTVPYDHAVPANPNRRQTMDSSKYSIYGTNVPPQ- 1127
            |.|..      .|..:|.....:.:...|| |:.|.|. ||      .:|..::||  .:..||
Zfish   976 PDICQAAYTDYRQPPVDYRHPPVADYRQPP-TMEYRHP-PA------LIDYRQHSI--ADYRPQD 1030

  Fly  1128 ------QQQPGVGGDTAAVRPQSLYGIN------APDLPPRIDRQSKPGDIPLNTSGSSSRNGTL 1180
                  :.:..|.|...::|....|.::      |.|.|...:.:.:.||..:..:|.|:|:.:.
Zfish  1031 YDYFTVELEKSVKGFGFSIRGGREYKMDLFVLRLAEDGPAVRNGRMRVGDQIIEINGESTRDMSH 1095

  Fly  1181 GRSAQ 1185
            .|:.:
Zfish  1096 ARAIE 1100

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pyd	NP_001246998.1	PDZ_signaling	249..334	CDD:238492	22/77 (29%)
		PDZ_signaling	396..477	CDD:238492	18/83 (22%)
		PDZ_signaling	633..710	CDD:238492	21/93 (23%)
		SH3_ZO	729..790	CDD:212793	9/62 (15%)
		GuKc	831..1007	CDD:214504	33/198 (17%)
		ZU5	2263..2351	CDD:279170
magi2b	XP_021326360.1	NK	<1..>29	CDD:327404
		MAGI_u1	35..96	CDD:318800
		WW	145..175	CDD:238122
		WW	190..219	CDD:306827
		PDZ	266..349	CDD:214570	22/79 (28%)
		PDZ	451..531	CDD:214570	18/86 (21%)
		PDZ	622..708	CDD:214570	25/152 (16%)
		PDZ_signaling	743..832	CDD:238492	18/117 (15%)
		PDZ_signaling	1034..1114	CDD:238492	13/67 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910