Protein Alignment CG8379 and ARMH3

DIOPT Version :10

• Sequence 1: NP_996185.1
• Gene: CG8379 / 41060
• FlyBaseID: FBgn0037638
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_078817.2
• Gene: ARMH3 / 79591
• HGNCID: 25788
• Length: 689
• Species: Homo sapiens
• Alignment Length: 694
• Identity: 327/694 - (47%)
• Similarity: 471/694 - (67%)
• Gaps: 28/694 - (4%)

  Fly     5 KRSG----SGSTKRP-KEKVVYIYELLCRGEDPSSESPEFWNEFFLLQPNFEALENEIGKLNNEQ 64
            ||.|    |.::|:| |||||.:|:.:...||||..||.||.|.||::.|.|.||.::..|:.|:
Human     6 KRGGLLRKSSASKKPLKEKVVLMYDEIFMTEDPSKCSPRFWEELFLMKVNLEYLEGKLESLDGEE 70

  Fly    65 LQLVKPNLNTLFQRCIEMLDTEDHPKRLCNSLHTLCSLFYGIFKKSNAEPTLNILNEIFGHEKMD 129
            |..:|.|:|.|||.||:.|. |:||.|:.|:|.|||:|..|:.:|:.:....:|:|.:.|.:|.:
Human    71 LMKIKDNINCLFQHCIQALG-EEHPIRVVNALQTLCALIRGVHQKNKSTSGFDIINMLMGFDKAE 134

  Fly   130 EWLKLLMQYCNRILLGDVPENARFMCLKLLQVLVTGTDNVNQNALFEHLMMHSMFDAFVRLLSDP 194
            ..:|.||:..:.:|..:..|:.:.:|||||..|||.|||::||.:.|::|::|:|:|.:::||.|
Human   135 LCMKNLMESLDSLLCAEGSESLKSLCLKLLLCLVTVTDNISQNTILEYVMINSIFEAILQILSHP 199

  Fly   195 TFRSQHGHDIVILLTILVNYRKHEATNPYVVQLSILADELALNGYGQMISQSLIDFCRQYIQSLN 259
            ..|.:||:|.|:||.:||||||:|:.|||:|:|||:.||..|||.|.:|:|:|.::.||| :...
Human   200 PSRREHGYDAVVLLALLVNYRKYESVNPYIVKLSIVDDEATLNGMGLVIAQALSEYNRQY-KDKE 263

  Fly   260 NVQSSSWFSSLSNIVGNMFVSDEGCERVQQIKANNGLLLALYEAVHLNRNFITTLAHTQAE---- 320
            ....|.:||:|:|:||:||::| ..|:: .::.|..:||||||||||||||||.||.:..|
Human   264 EEHQSGFFSALTNMVGSMFIAD-AHEKI-SVQTNEAILLALYEAVHLNRNFITVLAQSHPEMGLV 326

  Fly   321 ----SSAPPSPSNTLSLAQPVPD-LSNAPI-IDITQYPTNLLVAVFQYCSIVMQDNKNESSIANL 379
                |.||.:|...|....|..| :|:..: :|.....:|||:...:|.||||||.|:|..:.:.
Human   327 TTPVSPAPTTPVTPLGTTPPSSDVISSVELPLDADVQTSNLLITFLKYSSIVMQDTKDEHRLHSG 391

  Fly   380 KLCFLILTCISEDQYANSMMHDSNLTFKVMLHRAQMRHRKLNVDRVGKSQPLAATLLDLLVEFIV 444
            |||.:|||||:||||||:.:||.|:.|:|.|||..|||||...|:....:||...:|||:|||||
Human   392 KLCLIILTCIAEDQYANAFLHDDNMNFRVNLHRMPMRHRKKAADKNLPCRPLVCAVLDLMVEFIV 456

  Fly   445 SHLMKKFPMELYLLCIGVIHRILCYQKRCRVRLNYPWKELWSALIGLLRFLVNQEQTLVKKCNIF 509
            :|:||:|||:||:.||.|:|::|||||:|||||:|.|:|||||||.||:||::.|..|:.|.|||
Human   457 THMMKEFPMDLYIRCIQVVHKLLCYQKKCRVRLHYTWRELWSALINLLKFLMSNETVLLAKHNIF 521

  Fly   510 HLSLQVVNIFNLFITYGDTFLATTNSYDELYYELNREEKVFTEIHAMVLRYTTMPDCEYKDDVIK 574
            .|:|.:||:||:|||||||||.|.:||||||||:.|..:.|..:::||||.:|... ::|:...|
Human   522 TLALMIVNLFNMFITYGDTFLPTPSSYDELYYEIIRMHQSFDNLYSMVLRLSTNAG-QWKEAASK 585

  Fly   575 LLNALVNILAIVKHFQNKIKEWLAEQGLSTPTEEQILDVVRKNYD-LTLKLQDSLDQYERYTETP 638
            :.:|||||.||:.||..||:.:.|...:|..:|||:|:|||.||| |||||||.|||||||:|..
Human   586 VTHALVNIRAIINHFNPKIESYAAVNHISQLSEEQVLEVVRANYDTLTLKLQDGLDQYERYSEQH 650

  Fly   639 LHTNFFKLMVRDVVNDTRKHIYGYVKEAVSVIPDQEILLSSSMT 682
            ....|||.:||.:..:.|:::..:..       .||:||....|
Human   651 KEAAFFKELVRSISTNVRRNLAFHTL-------SQEVLLKEFST 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8379	NP_996185.1	ARMH3_C	429..657	CDD:462473	127/228 (56%)
ARMH3	NP_078817.2	ARMH3_C	441..669	CDD:462473	127/228 (56%)