Protein Alignment CG8379 and SPBC20F10.02c

DIOPT Version :9

• Sequence 1: NP_996185.1
• Gene: CG8379 / 41060
• FlyBaseID: FBgn0037638
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_596366.1
• Gene: SPBC20F10.02c / 2540697
• PomBaseID: SPBC20F10.02c
• Length: 600
• Species: Schizosaccharomyces pombe
• Alignment Length: 638
• Identity: 127/638 - (19%)
• Similarity: 250/638 - (39%)
• Gaps: 137/638 - (21%)

  Fly    18 KVVYIYELLCRGEDPSSESPEFWNEFFLLQPNFEALENEIGKLNNEQLQLVKPNLNTLFQRCIEM 82
            |:|:.|:.|.........:..||.|||||||..|.|...:.:...::|.:..|..::::....|:
pombe    12 KIVFYYKCLLNKNWNEPINNIFWGEFFLLQPRLEVLSQLLRECPKQELTVNGPKFHSMYLYISEI 76

  Fly    83 LDTEDHPKRLCNSLHTLCSLFYGIFKKSNAEPTLNILNEIFGHEKMDEWLKLLMQYCNRILLGDV 147
            |.::....|:.|||.||.:.   :.:.|..:|| ::...||                  :|||::
pombe    77 LKSKAESLRIRNSLATLQTF---LAELSVRKPT-DVNFTIF------------------LLLGNI 119

  Fly   148 PE-NARFMC-LKLLQVLVTGTDNVNQNALFEHLMMHSMFDAFVRLLSDPTFRSQ-HG-HDIV-IL 207
            .. :.:|.. :|.|..||..:::|....:....::|     ||..|.:.:|.|. :| :|:. .|
pombe   120 DSIDIQFSAFIKNLCQLVKDSEDVQSVEISLRFVLH-----FVSFLYNSSFISHIYGNYDVFSTL 179

  Fly   208 LTILVNYR-----------------KHEATNPYVVQLSILADELALNGYGQMISQSLIDFCRQYI 255
            .|:::..:                 |.|..|.:.:.||.:.||...:......:|.||.. |.:.
pombe   180 YTVILKRKFGFETAVYAIGLLSACDKFETVNTFRLGLSKIVDEEFFSSVLSSSAQQLISL-RDFY 243

  Fly   256 QSL--NNVQSSSWFS--SLSNIVGNMFVSDEG-CERVQQIKANNGLLLALYEAVHLNRNFITTLA 315
            .|:  :|..:.|:|:  ||.:...|.....|. ..|:...:|.  :...:||....|:.|:..|.
pombe   244 VSIKPDNPLTGSFFNLFSLRSSSNNPDSDQESQFSRLPDERAT--MFFTIYELCCCNKLFLKKLV 306

  Fly   316 HTQAESSAPPSPSNTLSLAQPVPDLSNAPIIDITQYPTNLLVAVFQYCSIVMQDNKNESSIANLK 380
            ....::.                           :.|...|:::..|.:...:.::.....:.|.
pombe   307 EGGEKNG---------------------------EAPLEALLSLLSYINTHQRQSERSHHFSILS 344

  Fly   381 LCFLILTCISEDQYANSMMHDSNLTFKVMLHRAQMRHRKLNVDRVGKSQPL------AATLLDLL 439
            |  ::...|.:|              :.:|:|...:..|::|....:..|.      .||.|..:
pombe   345 L--ILFHIIIDD--------------RSLLYRLTDKKFKISVRVCSQRYPYPPNATKPATPLGYM 393

  Fly   440 VEFI---VSHLMK-KFPMELYLLCIGVIHRILCYQKRCRVRLNYPWKELWSALIGLLRF---LVN 497
            ::..   :.|.|| .....:|.|....::|.:....:..:|:.|.|.|||..|...|.|   |:|
pombe   394 LDICCIGIQHNMKLNLSATMYFLYFSFVYRAMTSLVQDGIRMEYHWLELWRVLFSFLDFVSVLIN 458

  Fly   498 QEQTLVKKCNIFHLSLQVVNIFNLFITYGDTFLATTNSYDELYYELNREEKVFTEIHAMVLRYTT 562
            ...|.    ::..|...::::....|:.||..:..::...:|:|:|....|.|:...:.:
pombe   459 TSPTE----DVTRLLELILDVLAYIISNGDALVIRSDELVDLFYKLLHSSKNFSSFSSKI----- 514

  Fly   563 MPDCEYKDDVIKLLNALVNILAIVKHFQNKIKEWLAEQGLSTPTEEQILDVVR 615
             ||        :.|.||..:|.:.::..:|..:      |...|.:::..|::
pombe   515 -PD--------ERLGALNYLLEVTEYLTSKTVD------LPRSTADEVESVIK 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8379	NP_996185.1	DUF1741	424..657	CDD:285607	41/205 (20%)
SPBC20F10.02c	NP_596366.1	DUF1741	388..>502	CDD:285607	27/117 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	50	1.000	Domainoid score	I3388
eggNOG	1	0.900	-	-		E1_KOG4654
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H15843
Inparanoid	1	1.050	71	1.000	Inparanoid score	I1918
OMA	1	1.010	-	-		QHG56074
OrthoFinder	1	1.000	-	-		FOG0006424
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_105340
Panther	1	1.100	-	-	LDO	PTHR13608
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1859
SonicParanoid	1	1.000	-	-		X5382
TreeFam	0	0.000	Not matched by this tool.
	12	11.900