DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hng2 and madf-10

DIOPT Version :9

Sequence 1:	NP_649837.1	Gene:	hng2 / 41056	FlyBaseID:	FBgn0037634	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_492729.1	Gene:	madf-10 / 190925	WormBaseID:	WBGene00013717	Length:	234	Species:	Caenorhabditis elegans

Alignment Length:	206	Identity:	40/206 - (19%)
Similarity:	84/206 - (40%)	Gaps:	53/206 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VLRSAGSNLRYSMYEFIDAVHKRSIIWERSHPNFHNRELRDEAWQQIGHELCSNFDDSSEPEKQE 70
            ::|....::|::|.|   |:..|..:|:.:      ||....|.::      :.|.:..|...|:
Worm    41 MMRQVTDSVRFAMCE---AIAHRPGLWDST------REKVSSAARK------NLFAEVVEVINQQ 90

  Fly    71 IV-------KTLLKRWKNTRDSYLRVNR---LRQSGEEVARASYIYEKELSFLLNVKAESEDDVE 125
            .|       :.:.|.|||.:|:|::..|   ....|..: |..:.:...|.||.:|   :::|.
Worm    91 FVLSPPLTIEEIEKHWKNLKDTYVKTRRKLTFDHDGCPI-RPKWKFFDSLMFLDSV---NQNDF- 150

  Fly   126 SLKEQPK------------PQAKRKRVSTAAQ-------RSAKTPRKRNSDQES----NIEPAIR 167
            .:|::|.            |.:|::::.....       ||...|.|....::.    .|:.:||
Worm   151 VMKKRPMQFQGQPYDLYQGPSSKKEKLEEMPSDEYMEFCRSLYLPLKEIGYKDRIHWLKIQKSIR 215

  Fly   168 NPAIPSNINTV 178
            :....:.:.:|
Worm   216 DIVYEAQLESV 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hng2	NP_649837.1	MADF_DNA_bdg	21..113	CDD:287510	20/101 (20%)
hng2	NP_649837.1	BESS	216..250	CDD:281011
madf-10	NP_492729.1	MADF	53..147	CDD:214738	25/112 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156205
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001895
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.930