DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9839 and PGBD5

DIOPT Version :9

Sequence 1:	NP_001262388.1	Gene:	CG9839 / 41055	FlyBaseID:	FBgn0037633	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	NP_001245240.1	Gene:	PGBD5 / 79605	HGNCID:	19405	Length:	524	Species:	Homo sapiens

Alignment Length:	500	Identity:	103/500 - (20%)
Similarity:	182/500 - (36%)	Gaps:	122/500 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 EQQESDSDEDGYSELDYQAEDVFCQDDMDDYDPDWSS----------QQTGSRLLFKFPIQQSGL 132
            :.||.:.||.|                     ..||:          :.||.... |.|...|.:
Human    81 DAQEPEEDEAG---------------------AGWSAALRDRPPPRFEDTGGPTR-KMPPSASAV 123

  Fly   133 KFGQRFQGPQHYFNQVLGNRSKFFSSLAQSCNLKGGELKSNPTTAEEMEIFMALSLLMCDLKLEH 197
            .|.|.|. |.:....::...:.:.....:.....|..::   .|..||:.|:...:.......|.
Human   124 DFFQLFV-PDNVLKNMVVQTNMYAKKFQERFGSDGAWVE---VTLTEMKAFLGYMISTSISHCES 184

  Fly   198 LSDYWSTNMFYGLVGFSGKIPLERYQQLL---HCLNFDAPQLQAGRAKVKNSLLLDFINERMEEI 259
            :...||.. ||.....:..:...|::::|   |.:.|.:.|...|..||:.  .||.:....:..
Human   185 VLSIWSGG-FYSNRSLALVMSQARFEKILKYFHVVAFRSSQTTHGLYKVQP--FLDSLQNSFDSA 246

  Fly   260 YICGQQLVLNEPITLWKGALRYQDELP-------------NKFRTNALLLHMLTEQSGLVVKILP 311
            :...|..||:||:.         ||.|             .|.|..:|.:...: .:|.:::|..
Human   247 FRPSQTQVLHEPLI---------DEDPVFIATCTERELRKRKKRKFSLWVRQCS-STGFIIQIYV 301

  Fly   312 EIVRKE----DAPAWVRNSRQLVEHRNKIVLKLMEGYHGGRT--VYTSKFYGSYGLAQELAKKST 370
            .:  ||    |....::|..||    :.:|.:.:.....|:.  ::|.....|..|.:|..|:..
Human   302 HL--KEGGGPDGLDALKNKPQL----HSMVARSLCRNAAGKNYIIFTGPSITSLTLFEEFEKQGI 360

  Fly   371 YCTGLLDRNRYGNSKALVHQRLDSNSISTSYATSLMMAKWRRRAK---SLYCFSSDCLAIYSKEM 432
            ||.||| |.|..:...|      ..|:.|:.||.....:::.:.|   ||.|:       |:|..
Human   361 YCCGLL-RARKSDCTGL------PLSMLTNPATPPARGQYQIKMKGNMSLICW-------YNKGH 411

  Fly   433 AMQKTNAKPKLIQELEFQLRPGN--------------------DGRHHLIHYQAACKELKANIKL 477
            ....|||...:.|.:..:.:.|.                    |.::.  .|..:.|..|...::
Human   412 FRFLTNAYSPVQQGVIIKRKSGEIPCPLAVEAFAAHLSYICRYDDKYS--KYFISHKPNKTWQQV 474

  Fly   478 TIFLLNILVYNAYLLYFANGQNARVGHLKSYS--EFRVIIIKSLL 520
            ..|.::|.:.|||:||    :.:...|:|.||  :|...:::.||
Human   475 FWFAISIAINNAYILY----KMSDAYHVKRYSRAQFGERLVRELL 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9839	NP_001262388.1	DDE_Tnp_1_7	141..490	CDD:290555	77/393 (20%)
CG9839	NP_001262388.1	Tnp_zf-ribbon_2	570..602	CDD:290554
PGBD5	NP_001245240.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	30..117		10/57 (18%)
PGBD5	NP_001245240.1	DDE_Tnp_1_7	121..487	CDD:316368	81/404 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1139412at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920