Protein Alignment CCT7 and CCT6A

DIOPT Version :10

• Sequence 1: NP_649835.1
• Gene: CCT7 / 41054
• FlyBaseID: FBgn0037632
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001753.1
• Gene: CCT6A / 908
• HGNCID: 1620
• Length: 531
• Species: Homo sapiens
• Alignment Length: 536
• Identity: 151/536 - (28%)
• Similarity: 270/536 - (50%)
• Gaps: 23/536 - (4%)

  Fly     8 LKEGTDSSQGKPQLVSNINACQSIVDAVRTTLGPRGMDKLIVDAHGKATISNDGATIMKLLEIIH 72
            |....:.::.:..|..||:|.:.:.|.:||.|||:|..|::|...|...::.||..::..::|.|
Human     7 LNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQH 71

  Fly    73 PAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQVKPFVEEGVHPRVIIKAIRKALQLCMEKINE 137
            |.|..:..:|.:||...||||||.||:.||.|||...::.||:|||:|.:....|.:..::.:.|
Human    72 PTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEE 136

  Fly   138 MAVQIVEQSKDQQRALLEKCAATAMSSKLIHQQKDFFSRIVVDAVLSL---DELLPLNMIGIKKV 199
            :.|     |::..|..|...|.|::.:|:..:..|..:..|||::|::   ||.:.|.||.|.::
Human   137 VKV-----SREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPIDLFMIEIMEM 196

  Fly   200 TGGSLEESQLVSGVAFKKTFSYAGFEMAPKSYDNCKIALLNIELELKAERDNAEIRVDNVKEYQK 264
            ...|..::.|:.|:.......:...:   |..::..|...|:.||.:....|:.....:.:|.:|
Human   197 KHKSETDTSLIRGLVLDHGARHPDMK---KRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREK 258

  Fly   265 VVDAEWQILYNKLAKIHE---------SGANVVLSKLPIGDVATQYFADRDIFCAGRVPEEDLKR 320
            :|.||.:.:.:::.||.|         ....||:::..|...:....:...|....|....:::|
Human   259 LVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAKRRNMER 323

  Fly   321 TMKACGGAVMTTANDIKPNVLGLCEHFEERQVGGERFNLFQGCPNAKTSTLILRGGAEQFLEETE 385
            ...||||..:.:.:|:.|:.||......|..:|.|:|...:.|.|.::.||:::|..:..|.:.:
Human   324 LTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIK 388

  Fly   386 RSLHDAIMIVRRTIKHDSVVAGGGAIEMELSKLLRDYSRTIAGKEQLLIAAIAKGLEIIPRQLCD 450
            .::.|.:..|:..|....||.|.||:|:.:::.|..:..::.|:.||.:.|.|..|.|||:.|..
Human   389 DAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQ 453

  Fly   451 NAGFDATNILNKLRQKHAQGGQWYGVDINKEDISDNYEQCVWEPSIIKINALTAAAEAACMILSV 515
            |:|||....|.|::.:|::.||..|||:|..:.....|..||:...:|...|.:....|..||.|
Human   454 NSGFDLQETLVKIQAEHSESGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLV 518

  Fly   516 DETIKSPKAGEPPMAG 531
            ||.:   :||...:.|
Human   519 DEIM---RAGMSSLKG 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT7	NP_649835.1	TCP1_eta	4..524	CDD:239456	148/527 (28%)
CCT6A	NP_001753.1	chap_CCT_zeta	3..530	CDD:274088	150/533 (28%)