Protein Alignment CCT7 and CCT8

DIOPT Version :10

• Sequence 1: NP_649835.1
• Gene: CCT7 / 41054
• FlyBaseID: FBgn0037632
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_012526.1
• Gene: CCT8 / 853447
• SGDID: S000003545
• Length: 568
• Species: Saccharomyces cerevisiae
• Alignment Length: 568
• Identity: 164/568 - (28%)
• Similarity: 271/568 - (47%)
• Gaps: 66/568 - (11%)

  Fly     3 PQIVLLKEGTDS-SQGKPQLVSNINACQSIVDAVRTTLGPRGMDKLIVDAHGKATISNDGATIMK 66
            |...|.|:|.:| |....|::.:|.|.:.:.....|::||.|.:|:||:..||..|:||.||:::
Yeast     9 PNAGLFKQGYNSYSNADGQIIKSIAAIRELHQMCLTSMGPCGRNKIIVNHLGKIIITNDAATMLR 73

  Fly    67 LLEIIHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQVKPFVEEGVHPRVIIKAIRKALQLC 131
            .|:|:|||.|.||...:.|..::||||..|::||||.|...:..:..|:....||:....|.:..
Yeast    74 ELDIVHPAVKVLVMATEQQKIDMGDGTNLVMILAGELLNVSEKLISMGLSAVEIIQGYNMARKFT 138

  Fly   132 MEKINEMAVQIVEQSKDQQRALLEKCAATAMSSKLIHQQKDFFSRIVVDAVLSLDELLP------ 190
            :::::||.|..:....|:...|  |.....:|||. :..:|..|.:|.:||   ..:||
Yeast   139 LKELDEMVVGEITDKNDKNELL--KMIKPVISSKK-YGSEDILSELVSEAV---SHVLPVAQQAG 197

  Fly   191 ------LNMIGIKKVTGGSLEESQLVSGVAFK-------------KTFSYAGFEMAPKSYDNCKI 236
                  ::.|.:.|:.||||..|.::.|:.|.             |....|.|        .|.:
Yeast   198 EIPYFNVDSIRVVKIMGGSLSNSTVIKGMVFNREPEGHVKSLSEDKKHKVAVF--------TCPL 254

  Fly   237 ALLNIELELKAERDNAEIRVDNVKEYQKVVDAEWQILYNKLAKIHESGANVVLSKLPIGDVATQY 301
            .:.|.|.:......||:..:|..|..:|.:||       .:.:|.:.|...:::...:|::|..|
Yeast   255 DIANTETKGTVLLHNAQEMLDFSKGEEKQIDA-------MMKEIADMGVECIVAGAGVGELALHY 312

  Fly   302 FADRDIFCAGRVPEE-DLKRTMKACGGAVMTTANDIKPNVLGLCEHFEERQVGGERFNLF---QG 362
            .....|... :||.: :|:|..:.||...:.......|..|||.|..:..::||:|..:|   ||
Yeast   313 LNRYGILVL-KVPSKFELRRLCRVCGATPLPRLGAPTPEELGLVETVKTMEIGGDRVTVFKQEQG 376

  Fly   363 CPNAKTSTLILRGGAEQFLEETERSLHDAIMIVRRTIKHD--SVVAGGGAIEMELSKLLRDYSRT 425
             ..::|||:||||..:..|::.||::.|.:..|:..:|..  .::.|.||.|:||...:..|...
Yeast   377 -EISRTSTIILRGATQNNLDDIERAIDDGVAAVKGLMKPSGGKLLPGAGATEIELISRITKYGER 440

  Fly   426 IAGKEQLLIAAIAKGLEIIPRQLCDNAGFDATNILNKLRQKH--AQGGQ------WYGVDI---N 479
            ..|..||.|...|...|::||.|.:.||.|...:|..|...|  .:.|.      :.||||   :
Yeast   441 TPGLLQLAIKQFAVAFEVVPRTLAETAGLDVNEVLPNLYAAHNVTEPGAVKTDHLYKGVDIDGES 505

  Fly   480 KEDISDNYEQCVWEPSIIKINALTAAAEAACMILSVDETIKSPKAGEP 527
            .|.:.|..|:.:::....|..|:..|.|||..:||:|:.|.:.|||.|
Yeast   506 DEGVKDIREENIYDMLATKKFAINVATEAATTVLSIDQIIMAKKAGGP 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT7	NP_649835.1	TCP1_eta	4..524	CDD:239456	159/562 (28%)
CCT8	NP_012526.1	chap_CCT_theta	9..559	CDD:274087	164/568 (29%)