Protein Alignment CCT7 and Mkks

DIOPT Version :9

• Sequence 1: NP_649835.1
• Gene: CCT7 / 41054
• FlyBaseID: FBgn0037632
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001135418.1
• Gene: Mkks / 59030
• MGIID: 1891836
• Length: 570
• Species: Mus musculus
• Alignment Length: 587
• Identity: 113/587 - (19%)
• Similarity: 212/587 - (36%)
• Gaps: 111/587 - (18%)

  Fly    18 KPQLVSNINACQS---IVDAVRTTL-----------GPRGMDKLIVDAHGKAT-ISNDGATIMKL 67
            ||.|      |::   ..:.||:||           ||.|..|.:.:..|... .::..:.:::.
Mouse     8 KPSL------CKTEPLTSEKVRSTLSVLKGVIASCYGPSGRLKQLHNGLGGCVYTTSQSSALLRN 66

  Fly    68 LEIIHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQVKPFVEEGVHPRVIIKAIRKALQLCM 132
            |.:.||..|.|....::..:...|......:|....::.::..   .:.|...||..:..|.||.
Mouse    67 LSVTHPVLKILTSSVQNHVSCFSDCGLFTAILCCNLIENIQRL---DLTPATAIKLNKYLLSLCT 128

  Fly   133 EKINEMA----VQIVEQSKDQQRALLEKCAATAMSSKLIHQQKDFFSRIVVDAVL-----SLDEL 188
            ..:...|    :.:..:|.....:|:.....:..:..|..::.|....:::.|.|     |.:|.
Mouse   129 SYLKSEACSCRIPVDFRSTHTFLSLVHSILTSKPACMLTRKETDHIGALILKAFLLTIPESTEER 193

  Fly   189 LPLNMIGIKKVTGGSLEESQLVSGVAFKKTFSYAGFEMAPKSYDNCKIALLNIELELKAERDNAE 253
            :.|....|..:.|..:.:|.::.|:..:.:.......:..:.....::||..  ..|..:..||.
Mouse   194 MVLGKSIIVPLKGQRVTDSTVLPGLLIEASEVQLRRLLPTQKASGLRVALFC--TSLSGDFSNAG 256

  Fly   254 IRVDNVKEYQKVVDAEWQI---------LYNKLAKIHESGANVVLSKLPIGDVATQYFADRDIFC 309
                     :.||.|.:|:         |.|...::.....::||.:..|.....|:|::|.:..
Mouse   257 ---------EGVVVAHYQVSLENAVLEQLLNLGRRLVTDHVDLVLCQKVIHPSLKQFFSERHVMA 312

  Fly   310 AGRVPEEDLKRTMKACGGAVMTTANDIKPNVLGLCEHFEERQVGGERFNLFQGCPN-AKTSTLIL 373
            ..||....::...|..|...:.:.|.|.....|..:.....:.|.:.|  |...|| |...||:|
Mouse   313 IDRVGVTLMESLSKVTGATPIGSLNPIVSTTYGSVKDVCSARFGSKHF--FHLLPNEATVCTLLL 375

  Fly   374 RGGAEQFLEETERSLHDAIMIVRRTIKHDSVVAGGGAIEMELS------------KLLRDYSRTI 426
            ....:...||.:.:...|:.:::.|||...|:.|||..|..|:            .::||...|.
Mouse   376 CSRNDTAWEELKLTCQTAMHVLQLTIKEPWVLLGGGCTETHLAAYVRHKVHHEAEAIVRDDGCTQ 440

  Fly   427 AGKEQLLIAAIAKGLEIIPRQLCDNAGFDATNILNKLRQKH--------AQGGQW--------YG 475
            | |..:...|....||.:...|..:.|    .||...:..|        |..|.|        .|
Mouse   441 A-KLHVAAEAFCSALESVAGSLEHDGG----EILIDTKYGHLWSCQADSASVGNWSDTLSRCGCG 500

  Fly   476 VDINKEDISDNYEQCVWEP----------------------SIIKINALTAAAEAACMILSVDET 518
            :..::|::|.:..:..:.|                      ...|::.|..|.|.|.:||.:...
Mouse   501 LYNSQEELSWSVLRSTYHPFAPQTCLPQAALGSASNLTVDCFTAKLSGLQVAVETANLILDLSYV 565

  Fly   519 IK 520
            |:
Mouse   566 IE 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT7	NP_649835.1	chap_CCT_eta	2..524	CDD:274086	113/587 (19%)
		TCP1_eta	4..524	CDD:239456	113/587 (19%)
Mkks	NP_001135418.1	Cpn60_TCP1	29..569	CDD:395068	105/560 (19%)
		Substrate-binding apical domain. /evidence=ECO:0000250|UniProtKB:Q9NPJ1	198..370		34/184 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810