DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCT7 and cct2

DIOPT Version :9

Sequence 1:	NP_649835.1	Gene:	CCT7 / 41054	FlyBaseID:	FBgn0037632	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_001006757.1	Gene:	cct2 / 448434	XenbaseID:	XB-GENE-1006535	Length:	535	Species:	Xenopus tropicalis

Alignment Length:	527	Identity:	176/527 - (33%)
Similarity:	287/527 - (54%)	Gaps:	13/527 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LLKEGTDSSQGKPQLVSNINACQSIVDAVRTTLGPRGMDKLIVDA--HGKATISNDGATIMKLLE 69
            :.|.|.|..:.:...:|:.....:|.|.|::||||:||||:::.:  ....|::||||||:|.:.
Frog    11 IFKAGADEEKAETARLSSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDSTVTVTNDGATILKAIG 75

  Fly    70 IIHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQVKPFVEEGVHPRVIIKAIRKALQLCMEK 134
            |.:|||:.|||::|.||.|||||||||.:||.|.|::.:..|...:||:.||...|:|.|:..|.
Frog    76 IDNPAAQVLVDMSKVQDDEVGDGTTSVTVLAAELLREAEVLVARKIHPQTIISGWRQATQVAREA 140

  Fly   135 INEMAVQIVEQSKDQQ--RALLEKCAATAMSSKLIHQQKDFFSRIVVDAVLSLDELLPLNMIGIK 197
            :...:   |:...|::  |..|...|.|.:||||:...||.||::.|:|||.|.....|..|.:.
Frog   141 LLNAS---VDHGNDEEKFRCDLLNIARTTLSSKLLTHHKDHFSKLAVEAVLRLKGSGNLEAIHVI 202

  Fly   198 KVTGGSLEESQLVSGVAFKKTFSYAGFEMAPKSYDNCKIALLNIELEL-KAERDNAEIRVDNVKE 261
            |..||||.||.|..|....|....    ..||..:|.||.:.|..::. |.:...:.:|||:..:
Frog   203 KKLGGSLTESYLDEGFLLDKKIGV----NQPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAK 263

  Fly   262 YQKVVDAEWQILYNKLAKIHESGANVVLSKLPIGDVATQYFADRDIFCAGRVPEEDLKRTMKACG 326
            ..::..||.:.:..|:.:|.:.|.|..:::..|.:...|.||...:..........::|.....|
Frog   264 VAEIELAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFATAGVMAIEHADFAGVERLALVTG 328

  Fly   327 GAVMTTANDIKPNVLGLCEHFEERQVGGERFNLFQGCPNAKTSTLILRGGAEQFLEETERSLHDA 391
            |.:.:|.:..:...||.|:..||..:|.::...|.|....:..|::|||..:|.|:|.|||||||
Frog   329 GEIASTFDHPELVKLGTCKLIEEVMIGEDKLIHFSGVAMGEACTIVLRGATQQILDEAERSLHDA 393

  Fly   392 IMIVRRTIKHDSVVAGGGAIEMELSKLLRDYSRTIAGKEQLLIAAIAKGLEIIPRQLCDNAGFDA 456
            :.::.:|:|....|.|||..||.::..:.:.:....|||.:.:.:.||.|.::|..:.||||:|:
Frog   394 LCVLAQTVKDTRTVYGGGCSEMLMAHAVTELAIRTPGKESVAMESFAKALRMLPTIIADNAGYDS 458

  Fly   457 TNILNKLRQKHAQGGQWYGVDINKEDISDNYEQCVWEPSIIKINALTAAAEAACMILSVDETIK- 520
            .:::::||..|::|...||:|:....|.:..|..:.|...:|...|.:|:|||.:||.||..||
Frog   459 ADLVSQLRAAHSEGKSTYGLDMKNGTIGEMGELGITESFQVKRQVLLSASEAAEVILRVDNIIKA 523

  Fly   521 SPKAGEP 527
            :|:...|
Frog   524 APRKRVP 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT7	NP_649835.1	chap_CCT_eta	2..524	CDD:274086	175/522 (34%)
CCT7	NP_649835.1	TCP1_eta	4..524	CDD:239456	175/522 (34%)
cct2	NP_001006757.1	TCP1_beta	11..527	CDD:239452	175/522 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60896
OrthoDB	1	1.010	-	-		D205390at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930