DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCT7 and cct7

DIOPT Version :9

Sequence 1:	NP_649835.1	Gene:	CCT7 / 41054	FlyBaseID:	FBgn0037632	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_001032347.1	Gene:	cct7 / 407957	XenbaseID:	XB-GENE-988120	Length:	542	Species:	Xenopus tropicalis

Alignment Length:	543	Identity:	404/543 - (74%)
Similarity:	472/543 - (86%)	Gaps:	5/543 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQPQIVLLKEGTDSSQGKPQLVSNINACQSIVDAVRTTLGPRGMDKLIVDAHGKATISNDGATIM 65
            |...::|||||||:|||.|||||||||||.|.:|||||||||||||||||..||||||||||||:
Frog     2 MPTPVILLKEGTDTSQGVPQLVSNINACQVIAEAVRTTLGPRGMDKLIVDDRGKATISNDGATIL 66

  Fly    66 KLLEIIHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQVKPFVEEGVHPRVIIKAIRKALQL 130
            |||:::|||||||||||||||||||||||||.|||.||:|||||:||||:||::||:|.|.|.||
Frog    67 KLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFMKQVKPYVEEGLHPQIIIRAYRTATQL 131

  Fly   131 CMEKINEMAVQIVEQSKDQQRALLEKCAATAMSSKLIHQQKDFFSRIVVDAVLSLDELLPLNMIG 195
            .:.||.|:||.:.::.|::||.|||||||||:|||||..|||||:::|||||..||:||.|.|||
Frog   132 AVGKIREIAVTVKKEDKEEQRLLLEKCAATALSSKLIALQKDFFAKMVVDAVSLLDDLLQLKMIG 196

  Fly   196 IKKVTGGSLEESQLVSGVAFKKTFSYAGFEMAPKSYDNCKIALLNIELELKAERDNAEIRVDNVK 260
            ||||.||:||:|.||:|||||||||||||||.||.|::.||:|||:|||||||:||||:||.|::
Frog   197 IKKVQGGALEDSHLVAGVAFKKTFSYAGFEMQPKKYESPKISLLNVELELKAEKDNAEVRVSNIE 261

  Fly   261 EYQKVVDAEWQILYNKLAKIHESGANVVLSKLPIGDVATQYFADRDIFCAGRVPEEDLKRTMKAC 325
            :||.:|||||.|||:||.||::|||.||||||||||||||||||||:|||||||||||||||.||
Frog   262 DYQAIVDAEWNILYDKLEKIYKSGAKVVLSKLPIGDVATQYFADRDLFCAGRVPEEDLKRTMMAC 326

  Fly   326 GGAVMTTANDIKPNVLGLCEHFEERQVGGERFNLFQGCPNAKTSTLILRGGAEQFLEETERSLHD 390
            ||::.|:.|.:..:|||.|..|||.||||||:|.|.|||.|||.|:|||||||||:|||||||||
Frog   327 GGSIQTSVNALTDDVLGHCALFEEAQVGGERYNFFTGCPKAKTCTIILRGGAEQFMEETERSLHD 391

  Fly   391 AIMIVRRTIKHDSVVAGGGAIEMELSKLLRDYSRTIAGKEQLLIAAIAKGLEIIPRQLCDNAGFD 455
            |||||||.||:||||||||||||||||.||||||||.||:||||.:.||.|||||||||||||||
Frog   392 AIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGSYAKALEIIPRQLCDNAGFD 456

  Fly   456 ATNILNKLRQKHAQGGQWYGVDINKEDISDNYEQCVWEPSIIKINALTAAAEAACMILSVDETIK 520
            |||||||||.||||||.|||||:|.|||:||::.|||||:|::|||||||:||||::||||||||
Frog   457 ATNILNKLRAKHAQGGMWYGVDVNNEDIADNFDACVWEPAIVRINALTAASEAACLVLSVDETIK 521

  Fly   521 SPKAGEPPMAGGGMGMGRGMGRP 543
            :|::     :..|...|||.|||
Frog   522 NPRS-----SMDGAPAGRGRGRP 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT7	NP_649835.1	chap_CCT_eta	2..524	CDD:274086	396/521 (76%)
CCT7	NP_649835.1	TCP1_eta	4..524	CDD:239456	396/519 (76%)
cct7	NP_001032347.1	TCP1_eta	5..525	CDD:239456	396/519 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	758	1.000	Domainoid score	I94
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H4694
Inparanoid	1	1.050	815	1.000	Inparanoid score	I468
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D205390at33208
OrthoFinder	1	1.000	-	-		FOG0004859
OrthoInspector	1	1.000	-	-		oto105359
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3429
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.060