DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCT7 and fab1

DIOPT Version :9

Sequence 1:	NP_649835.1	Gene:	CCT7 / 41054	FlyBaseID:	FBgn0037632	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_611269.1	Gene:	fab1 / 37033	FlyBaseID:	FBgn0028741	Length:	1809	Species:	Drosophila melanogaster

Alignment Length:	449	Identity:	93/449 - (20%)
Similarity:	168/449 - (37%)	Gaps:	120/449 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 SNDGATIMKLLEIIHPA---AKTLVDIAKSQDAEVGDGTTSVVL---LAGEFLKQVKPFVEE--- 113
            ||...|:.:.::...||   .:.|::...|.:....:.....:|   ||..||:.:.|..|:
  Fly   325 SNSLITLHEEMQRDLPAQNCGQRLIEFLNSNNKSANEVQAVAILNAMLAAGFLEPIVPDPEQMDF 389

  Fly   114 --GVHPRVIIKAIRKALQLCMEKINEMAVQI-------------VEQSKDQQRALLE------KC 157
              .:|       .:.:.....:....|:.|.             ::||.:::...||      :|
  Fly   390 DSSLH-------YKFSKSSSSDTSRTMSPQFEANPHAEPQPPKSMDQSAEEKEKELENELENDRC 447

  Fly   158 AATAMSSKLIHQQKDFFSRIVV------------DAVLSL---------------DELLPL-NMI 194
            ..|| :|||:....:...:::.            |.||.:               ::|:.: |.:
  Fly   448 YTTA-TSKLLASYCEHEEQLLAQMLRAHNLDQEWDKVLQMLCSTAANHFKPEHCSNDLMDIRNYV 511

  Fly   195 GIKKVTGGSLEESQLVSGVAFKKTFSYAGFEMA-------------PKSYDNCKIALLNIELELK 246
            ..|||.||..::|::|.||||.|..::.  :||             |..|:..:...:.||..|.
  Fly   512 NFKKVPGGRRKDSKIVHGVAFSKNVAHK--DMATHVPFPRILLLQCPIVYERIEGKFVTIETVLL 574

  Fly   247 AERDNAEIRVDNVKEYQKVVDAEWQILYNKLAKIHESGANVVLSKLPIGDVATQYFADRDIFCAG 311
            .|           |||          |.|..|:|.....||||....:..:|.......::....
  Fly   575 QE-----------KEY----------LRNVCARIMSFKPNVVLVHKNVAGIAQDLLRSYEVTLVL 618

  Fly   312 RVP---EEDLKRTMKACGGAVMTTANDIKPNVLGLCEHFEERQVGGERFNLFQGCPNAKTSTLIL 373
            .|.   .|.|.||::.  ..|.:..::|....||.|..|..|...|:....|:...|.:..|.:|
  Fly   619 DVKLSVMERLSRTLQC--DIVSSIESNITMPKLGYCNDFYIRNYNGKTLMFFEKLTNPRGYTCLL 681

  Fly   374 RGGAEQFLEETERSLHDAIMIVRRTIKHDSVVAGGGAIEMELSKLLRDYSRTIAGKEQL 432
            |||:...|...:| :..|::..|...:            :|:|.||.::::.::.|..:
  Fly   682 RGGSNAELTRVKR-VASALLFARYNWR------------LEMSFLLNEFAQPLSPKPSI 727

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT7	NP_649835.1	chap_CCT_eta	2..524	CDD:274086	93/449 (21%)
CCT7	NP_649835.1	TCP1_eta	4..524	CDD:239456	93/449 (21%)
fab1	NP_611269.1	FYVE_PIKfyve_Fab1	182..243	CDD:277264
		DEP	329..397	CDD:214489	13/74 (18%)
		Fab1_TCP	464..717	CDD:239450	65/290 (22%)
		PIPKc	1413..1797	CDD:295374
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453461
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930