DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCT7 and CCT8

DIOPT Version :9

Sequence 1:	NP_649835.1	Gene:	CCT7 / 41054	FlyBaseID:	FBgn0037632	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_610418.1	Gene:	CCT8 / 35882	FlyBaseID:	FBgn0284436	Length:	546	Species:	Drosophila melanogaster

Alignment Length:	538	Identity:	148/538 - (27%)
Similarity:	266/538 - (49%)	Gaps:	34/538 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LLKEGTDSSQGKPQLV-SNINACQSIVDAVRTTLGPRGMDKLIVDAHGKATISNDGATIMKLLEI 70
            :||:|.....|..:.| .||:||:.....:|:..||.||:|:|::...|..:::|..|||:.|::
  Fly    14 MLKDGARMYSGLEEAVFRNISACKEFAQTMRSAYGPNGMNKMIINHIEKQFVTSDAGTIMRELDV 78

  Fly    71 IHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQVKPFVEEGVHPRVIIKAIRKALQLCMEKI 135
            .|||||.:|..::.|||||||||..||:|||..|:..:..:..|:....|.....|||:..:|.:
  Fly    79 EHPAAKLIVMASQMQDAEVGDGTNFVVVLAGALLESAEELLRLGITTAEISDGYEKALEKALEIL 143

  Fly   136 NEMAVQIVEQSKDQQRALLEKCAATAMSSKLIHQQKDFFSRIVVDAVLSL--DE-LLPLNMIGIK 197
            ..:....:|..::.::  :::...|::.||. :.|:||.:.:|..|.:|:  || ...::.|.|.
  Fly   144 PNLVSHKIEDYRNVEK--VKEVLRTSIMSKQ-YGQEDFLNDLVSKACVSILPDEGTFNVDNIRIC 205

  Fly   198 KVTGGSLEESQLVSGVAFKKTFSYAGFEMAPKSY-DNCKIALLNIELELKAERDNAEIRVDNVKE 261
            |:.|..|.:|::|.|:.||:      |.....:| :..||.:.:..:::........:.:.:..|
  Fly   206 KILGSGLTKSEVVRGMVFKR------FVEGDVTYAEKAKIVIFSCPVDIIQTETKGTVLIKSADE 264

  Fly   262 YQKVVDAEWQILYNKLAKIHESGANVVLSKLPIGDVATQYFADRDIFCAGRVPEEDLKRTMKACG 326
            .......|..:|.:::..|.::|..||::...:||:|..:.....:.......:.||:|..::..
  Fly   265 LLSFSSGEESLLESQIKAIADAGVKVVVAGGKVGDMALHFLNKYGLMAVRLNSKFDLRRLSRSVN 329

  Fly   327 GAVMTTANDIKPNVLGLCEHFEERQVGGERFNLFQG-CPNAKTSTLILRGGAEQFLEETERSLHD 390
            ..|:..........||.|:.....::|......|:. ..:::.:|:::||..:.|:::.||:|.|
  Fly   330 ATVLPRITTPSQEELGYCDKVCIEELGDTTIVAFRNEGKDSRIATVVIRGATDNFMDDIERALDD 394

  Fly   391 AIMIVRRTIKHDSVVAGGGAIEMELSKLLRDYSRTIAGKEQLLIAAIAKGLEIIPRQLCDNAGFD 455
            ||...:...:....:.|.||.|:||:..|..|:.|:.|.:|..:...|..||:.|:.|.:|:|.:
  Fly   395 AINNFKCLTRDGRYLPGAGATEIELATQLSAYADTLPGLDQYAVRKFANALEVFPKALAENSGIN 459

  Fly   456 ATNILNKLRQKH-AQGGQWYGVDINKEDIS----------DNYEQCVWEPSIIKINALTAAAEAA 509
            .|.|:|:|...| .:.|:..|.||..|..|          |.|:...|        .|..|..||
  Fly   460 GTEIVNQLYLAHNNEAGKTIGFDIEAEKASTIDTTKAKLFDLYQSKFW--------GLKYAVGAA 516

  Fly   510 CMILSVDETIKSPKAGEP 527
            ..||.||:.|.:.:||.|
  Fly   517 ATILKVDQIIMAKRAGGP 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT7	NP_649835.1	chap_CCT_eta	2..524	CDD:274086	145/533 (27%)
CCT7	NP_649835.1	TCP1_eta	4..524	CDD:239456	145/533 (27%)
CCT8	NP_610418.1	TCP1_theta	20..529	CDD:239457	142/525 (27%)
CCT8	NP_610418.1	Cpn60_TCP1	40..529	CDD:278544	136/505 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453430
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11353
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940