DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCT7 and CCT4

DIOPT Version :9

Sequence 1:	NP_649835.1	Gene:	CCT7 / 41054	FlyBaseID:	FBgn0037632	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_609579.1	Gene:	CCT4 / 34674	FlyBaseID:	FBgn0032444	Length:	533	Species:	Drosophila melanogaster

Alignment Length:	523	Identity:	176/523 - (33%)
Similarity:	290/523 - (55%)	Gaps:	24/523 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 DSSQGKPQLVSNINACQSIVDAVRTTLGPRGMDKLIVDAHGKATISNDGATIMKLLEIIHPAAKT 77
            |.|:.....:|||.|.:::.||:||:||||||||:|...:|:.:|:||||||:|.:.::|||||.
  Fly    19 DKSKPTDVRLSNIQAAKAVSDAIRTSLGPRGMDKMIQAGNGEVSITNDGATILKQMNVLHPAAKM 83

  Fly    78 LVDIAKSQDAEVGDGTTSVVLLAGEFLKQVKPFVEEGVHPRVIIKAIRKALQLCMEKINEMAVQI 142
            ||:::::||...||||||||::||..|:..:..:::|:||    .||..:.|.|..|..|:..|:
  Fly    84 LVELSRAQDVAAGDGTTSVVVIAGALLEACEKLLQKGLHP----TAISDSFQRCSNKAVEILKQM 144

  Fly   143 VEQSKDQQRALLEKCAATAMSSKLIHQQKDFFSRIVVDAVLSL-----DELLPLNMIGIKKVTGG 202
            ....:...|..|.|.|:|:::||::.||....:.|.|||||.:     :..:.|..|.:....||
  Fly   145 STPIELDDRETLIKSASTSLNSKVVSQQSSLLAPIAVDAVLKVTDPGKETSVDLKNIKVISSLGG 209

  Fly   203 SLEESQLVSGVAFKKTFSYAGFEMAPKSYDNCKIALLNIELEL-KAERDNAEIRVDNVKEYQKVV 266
            ::|:::||.|:.|  |...|| ..|||..:..||.|:...:.. |.:.|: .:.|.:.....:|:
  Fly   210 TVEDTELVDGLVF--TCRSAG-SNAPKRIEKAKIGLIQFCISAPKTDMDH-NVIVSDYAAMDRVL 270

  Fly   267 DAEWQILYNKLAKIHESGANVVLSKLPI-----GDVATQYFADRDIFC--AGRVPEEDLKRTMKA 324
            ..|...:.|.:.:|.:||.||:|.:..|     .|:| |:|.|: |.|  ...|..||::...|.
  Fly   271 KEERSYILNIVKQIKKSGCNVLLVQKSILRDAVSDLA-QHFLDK-IKCMVVKDVEREDIEFVCKT 333

  Fly   325 CGGAVMTTANDIKPNVLGLCEHFEERQVGGERFNLFQGCPN-AKTSTLILRGGAEQFLEETERSL 388
            .....:.:.:......|...:..||...|..:|....|..| .:|.::|.||..:..|||..|||
  Fly   334 LHCRPIASLDHFTAENLSSADLVEEVASGTNKFVKITGIQNMGRTVSIICRGSNKLVLEEAARSL 398

  Fly   389 HDAIMIVRRTIKHDSVVAGGGAIEMELSKLLRDYSRTIAGKEQLLIAAIAKGLEIIPRQLCDNAG 453
            |||:.:||..:|..:.:.||||.|:|::..|...::|:.|.:.....|.|..||:||..|.:|||
  Fly   399 HDALCVVRCLVKLRAQIVGGGAPEIEMALQLAALAQTVEGVDAYCFRAFADALEVIPSTLAENAG 463

  Fly   454 FDATNILNKLRQKHAQGGQWYGVDINKEDISDNYEQCVWEPSIIKINALTAAAEAACMILSVDET 518
            .:....:.:||.:||||.:..|:::.|..|:|.:.:.|.:|.::.|:::|.|.|....||.:|:.
  Fly   464 LNPIATVTELRNRHAQGEKNAGINVRKGAITDIFAENVVQPLLVSISSITLATETIRSILKIDDI 528

  Fly   519 IKS 521
            :.:
  Fly   529 VNT 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT7	NP_649835.1	chap_CCT_eta	2..524	CDD:274086	176/523 (34%)
CCT7	NP_649835.1	TCP1_eta	4..524	CDD:239456	176/523 (34%)
CCT4	NP_609579.1	TCP1_delta	18..531	CDD:239454	176/521 (34%)
CCT4	NP_609579.1	Cpn60_TCP1	37..529	CDD:278544	170/501 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453409
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11353
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840