DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCT7 and Cct7

DIOPT Version :9

Sequence 1:	NP_649835.1	Gene:	CCT7 / 41054	FlyBaseID:	FBgn0037632	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_001100073.1	Gene:	Cct7 / 297406	RGDID:	1306422	Length:	544	Species:	Rattus norvegicus

Alignment Length:	541	Identity:	408/541 - (75%)
Similarity:	470/541 - (86%)	Gaps:	3/541 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQPQIVLLKEGTDSSQGKPQLVSNINACQSIVDAVRTTLGPRGMDKLIVDAHGKATISNDGATIM 65
            |...::|||||||||||.|||||||:|||.|.:|||||||||||||||||..||||||||||||:
  Rat     2 MPTPVILLKEGTDSSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDGATIL 66

  Fly    66 KLLEIIHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQVKPFVEEGVHPRVIIKAIRKALQL 130
            |||:::|||||||||||||||||||||||||.|||.||||||||:||||:||::||:|.|.|.||
  Rat    67 KLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQL 131

  Fly   131 CMEKINEMAVQIVEQSKDQQRALLEKCAATAMSSKLIHQQKDFFSRIVVDAVLSLDELLPLNMIG 195
            .:.||.|:||.:.:|.|.:||.:|||||.||:|||||.|||.||:::|||||:.|||||.|.|||
  Rat   132 AVNKIKEIAVTVKKQDKVEQRKMLEKCAMTALSSKLISQQKVFFAKMVVDAVMMLDELLQLKMIG 196

  Fly   196 IKKVTGGSLEESQLVSGVAFKKTFSYAGFEMAPKSYDNCKIALLNIELELKAERDNAEIRVDNVK 260
            ||||.||:||||:||:|||||||||||||||.||.|.|.||||||:|||||||:|||||||..|:
  Rat   197 IKKVQGGALEESRLVAGVAFKKTFSYAGFEMQPKKYKNPKIALLNVELELKAEKDNAEIRVHTVE 261

  Fly   261 EYQKVVDAEWQILYNKLAKIHESGANVVLSKLPIGDVATQYFADRDIFCAGRVPEEDLKRTMKAC 325
            :||.:|||||.|||:||.|||:|||.|:||||||||||||||||||:|||||||||||||||.||
  Rat   262 DYQAIVDAEWNILYDKLEKIHQSGAKVILSKLPIGDVATQYFADRDMFCAGRVPEEDLKRTMMAC 326

  Fly   326 GGAVMTTANDIKPNVLGLCEHFEERQVGGERFNLFQGCPNAKTSTLILRGGAEQFLEETERSLHD 390
            ||::.|:.|.:.|:|||.|:.|||.|:||||:|.|.|||.|||.|:|||||||||:|||||||||
  Rat   327 GGSIQTSVNALIPDVLGRCQVFEETQIGGERYNFFTGCPKAKTCTIILRGGAEQFMEETERSLHD 391

  Fly   391 AIMIVRRTIKHDSVVAGGGAIEMELSKLLRDYSRTIAGKEQLLIAAIAKGLEIIPRQLCDNAGFD 455
            |||||||.||:||||||||||||||||.||||||||.||:||||.|.||.|||||||||||||||
  Rat   392 AIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFD 456

  Fly   456 ATNILNKLRQKHAQGGQWYGVDINKEDISDNYEQCVWEPSIIKINALTAAAEAACMILSVDETIK 520
            |||||||||.:|||||.|||||||.|||:||::..||||::::|||||||:||||:|:|||||||
  Rat   457 ATNILNKLRARHAQGGMWYGVDINNEDIADNFQAFVWEPAMVRINALTAASEAACLIVSVDETIK 521

  Fly   521 SPKA---GEPPMAGGGMGMGR 538
            :|::   ...|.||.|.|.||
  Rat   522 NPRSTVDAPAPAAGRGRGQGR 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT7	NP_649835.1	chap_CCT_eta	2..524	CDD:274086	400/521 (77%)
CCT7	NP_649835.1	TCP1_eta	4..524	CDD:239456	400/519 (77%)
Cct7	NP_001100073.1	TCP1_eta	5..525	CDD:239456	400/519 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343752
Domainoid	1	1.000	761	1.000	Domainoid score	I82
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4694
Inparanoid	1	1.050	819	1.000	Inparanoid score	I444
OMA	1	1.010	-	-		QHG60896
OrthoDB	1	1.010	-	-		D205390at33208
OrthoFinder	1	1.000	-	-		FOG0004859
OrthoInspector	1	1.000	-	-		oto98666
orthoMCL	1	0.900	-	-		OOG6_101782
Panther	1	1.100	-	-	LDO	PTHR11353
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3429
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770