DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCT7 and Cct5

DIOPT Version :9

Sequence 1:	NP_649835.1	Gene:	CCT7 / 41054	FlyBaseID:	FBgn0037632	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_001004078.1	Gene:	Cct5 / 294864	RGDID:	735161	Length:	541	Species:	Rattus norvegicus

Alignment Length:	530	Identity:	150/530 - (28%)
Similarity:	282/530 - (53%)	Gaps:	15/530 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VLLKEGTDSSQ--GKPQLVSNINACQSIVDAVRTTLGPRGMDKLIVDAHGKATISNDGATIMKLL 68
            :::|:....|:  |...|.|:|.|.:::.:.:||:|||.|:||::||..|..|::||||||:.::
  Rat    17 LIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMM 81

  Fly    69 EIIHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQVKPFVEEGVHPRVIIKAIRKALQLCME 133
            ::.|..||.:|:::||||.|:|||||.||:|||..|::.:..::.|:||..|.....:|.::.::
  Rat    82 DVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARIAIQ 146

  Fly   134 KINEMAVQIVEQSKDQQRALLEKCAATAMSSKLIHQQKDFFSRIVVDAVLSLDEL----LPLNMI 194
            .:::::..::....:.:.  |.:.|.|.:.||:::......:.|.|:|||::.::    :...:|
  Rat   147 HLDKISDNVLVDINNPEP--LIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELI 209

  Fly   195 GIKKVTGGSLEESQLVSGVAFKKTFSYAGFEMAPKSYDNCKIALLNIELELKAERDNAEIRVDNV 259
            .::...||.||:::|:.||...|.||:   ...||...|.|||:|....|....:...::.|.:|
  Rat   210 KVEGKVGGRLEDTKLIKGVIVDKDFSH---PQMPKEVLNAKIAILTCPFEPPKPKTKHKLDVTSV 271

  Fly   260 KEYQKVVDAEWQILYNKLAKIHESGANVVLSKLPIGDVATQYFADRDIFCAGRVPEEDLKRTMKA 324
            ::|:.:...|.:.....:|:|.|:|||:.:.:....|.|........:.....|...:::....|
  Rat   272 EDYKALQKYEKEKFEEMIAQIKETGANLAICQWGFDDEANHLLLQNGLPAVRWVGGPEIELIAIA 336

  Fly   325 CGGAVMTTANDIKPNVLGLCEHFEERQVG--GERFNLFQGCPNAKTSTLILRGGAEQFLEETERS 387
            .||.::...:::....||......|...|  .::..:.:.|.|::..|:.:|||.:..:||.:||
  Rat   337 TGGRIVPRFSELTSEKLGFAGVVREISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRS 401

  Fly   388 LHDAIMIVRRTIKHDSVVAGGGAIEMELSKLLRDYSRTIAGKEQLLIAAIAKGLEIIPRQLCDNA 452
            ||||:.::|..|:.:.||.||||.|:..:..:...:......||..:.|.|..||:||..|.:|:
  Rat   402 LHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENS 466

  Fly   453 GFDATNILNKLRQKHA-QGGQWYGVDINKEDISDNYEQCVWEPSIIKINALTAAAEAACMILSVD 516
            |.:....:.::|.:.. :.....|:|...:..:|...|.|.|..|.|...::.|.:...|||.:|
  Rat   467 GMNPIQTMTEVRARQVKESNPALGIDCLHKGSNDMQYQHVIETLIGKKQQISLATQMVRMILKID 531

  Fly   517 ETIKSPKAGE 526
            : |:.|...|
  Rat   532 D-IRKPGESE 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT7	NP_649835.1	chap_CCT_eta	2..524	CDD:274086	149/526 (28%)
CCT7	NP_649835.1	TCP1_eta	4..524	CDD:239456	149/526 (28%)
Cct5	NP_001004078.1	TCP1_epsilon	10..535	CDD:239455	148/523 (28%)
Cct5	NP_001004078.1	Cpn60_TCP1	44..533	CDD:278544	140/494 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60896
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820