DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCT7 and cct7

DIOPT Version :9

Sequence 1:	NP_649835.1	Gene:	CCT7 / 41054	FlyBaseID:	FBgn0037632	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_596355.1	Gene:	cct7 / 2540572	PomBaseID:	SPBC25H2.12c	Length:	558	Species:	Schizosaccharomyces pombe

Alignment Length:	552	Identity:	346/552 - (62%)
Similarity:	434/552 - (78%)	Gaps:	11/552 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 PQI--VLLKEGTDSSQGKPQLVSNINACQSIVDAVRTTLGPRGMDKLIVDAHGKATISNDGATIM 65
            |||  ::||||||.|||:.||:||||||.::.|.:||||||.|.|||:||..|:..|||||||||
pombe     6 PQIPVIVLKEGTDDSQGRGQLLSNINACVAVQDTIRTTLGPLGADKLMVDDRGEVVISNDGATIM 70

  Fly    66 KLLEIIHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQVKPFVEEGVHPRVIIKAIRKALQL 130
            |||:|:|||||||||||::|||||||||||||:.|||.|::.:.|||:||...:||:..|||.||
pombe    71 KLLDIVHPAAKTLVDIARAQDAEVGDGTTSVVVFAGELLREARTFVEDGVSSHLIIRGYRKAAQL 135

  Fly   131 CMEKINEMAVQIVEQSKDQQRALLEKCAATAMSSKLIHQQKDFFSRIVVDAVLSLD-ELLPLNMI 194
            .:.||.|:|:.:....:.:.|.||.|||:|||:||||.....||:::||||||:|| |.|..|||
pombe   136 AVNKIKEIAIHLDLSDEGKLRDLLTKCASTAMNSKLIRSNSTFFTKMVVDAVLTLDQEDLNENMI 200

  Fly   195 GIKKVTGGSLEESQLVSGVAFKKTFSYAGFEMAPKSYDNCKIALLNIELELKAERDNAEIRVDNV 259
            |||||.||::|:|.||.||||||||||||||..||.:.|.||..|::|||||||:||||:|||.|
pombe   201 GIKKVPGGAMEDSLLVKGVAFKKTFSYAGFEQQPKFFKNPKILCLDVELELKAEKDNAEVRVDKV 265

  Fly   260 KEYQKVVDAEWQILYNKLAKIHESGANVVLSKLPIGDVATQYFADRDIFCAGRVPEEDLKRTMKA 324
            :|||.:|||||:|:::||..|..:||.||||||||||:||||||||||||||||..:||.|.::|
pombe   266 QEYQNIVDAEWRIIFSKLEAIVATGAKVVLSKLPIGDLATQYFADRDIFCAGRVAADDLNRVVQA 330

  Fly   325 CGGAVMTTANDIKPNVLGLCEHFEERQVGGERFNLFQGCPNAKTSTLILRGGAEQFLEETERSLH 389
            .||::.:|.::|:...||.|:.|||||:||:|||||:|||.|||.||||||||:||:.|.|||||
pombe   331 VGGSIQSTCSNIEEKHLGTCDTFEERQIGGDRFNLFEGCPKAKTCTLILRGGADQFIAEVERSLH 395

  Fly   390 DAIMIVRRTIKHDSVVAGGGAIEMELSKLLRDYSRTIAGKEQLLIAAIAKGLEIIPRQLCDNAGF 454
            ||||||:..:|::.|||||||.||||||.|||||.||:||:|..|||.|:.||:|||||||||||
pombe   396 DAIMIVKHALKNNLVVAGGGACEMELSKYLRDYSLTISGKQQNFIAAFARSLEVIPRQLCDNAGF 460

  Fly   455 DATNILNKLRQKHAQGGQWYGVDINKEDISDNYEQCVWEPSIIKINALTAAAEAACMILSVDETI 519
            |:||||||||.:||:|..|.|||::.|.:::|:|:.|||||.:|.||:.:|.|||.:||||||||
pombe   461 DSTNILNKLRMQHAKGEMWAGVDMDSEGVANNFEKFVWEPSTVKSNAILSATEAATLILSVDETI 525

  Fly   520 K--------SPKAGEPPMAGGGMGMGRGMGRP 543
            |        :|:...||.|...:..|||.|.|
pombe   526 KNEPSQQPQAPQGALPPGAANRIMRGRGRGMP 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT7	NP_649835.1	chap_CCT_eta	2..524	CDD:274086	338/531 (64%)
CCT7	NP_649835.1	TCP1_eta	4..524	CDD:239456	337/530 (64%)
cct7	NP_596355.1	chap_CCT_eta	9..530	CDD:274086	334/520 (64%)
cct7	NP_596355.1	TCP1_eta	9..530	CDD:239456	334/520 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	627	1.000	Domainoid score	I22
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4694
Inparanoid	1	1.050	683	1.000	Inparanoid score	I109
OMA	1	1.010	-	-		QHG60896
OrthoFinder	1	1.000	-	-		FOG0004859
OrthoInspector	1	1.000	-	-		oto102062
orthoMCL	1	0.900	-	-		OOG6_101782
Panther	1	1.100	-	-	LDO	PTHR11353
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1489
SonicParanoid	1	1.000	-	-		X3429
TreeFam	1	0.960	-	-
	14	13.860