Protein Alignment CCT7 and Cct8

DIOPT Version :10

• Sequence 1: NP_649835.1
• Gene: CCT7 / 41054
• FlyBaseID: FBgn0037632
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_033970.3
• Gene: Cct8 / 12469
• MGIID: 107183
• Length: 548
• Species: Mus musculus
• Alignment Length: 542
• Identity: 145/542 - (26%)
• Similarity: 260/542 - (47%)
• Gaps: 34/542 - (6%)

  Fly     7 LLKEGTDSSQGKPQLV-SNINACQSIVDAVRTTLGPRGMDKLIVDAHGKATISNDGATIMKLLEI 70
            :||:|.....|..:.| .||.||:.:....||..||.||:|::::...|..::||.|||::.||:
Mouse    14 MLKDGAKHFSGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINRLEKLFVTNDAATILRELEV 78

  Fly    71 IHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQVKPFVEEGVHPRVIIKAIRKALQLCMEKI 135
            .|||||.:|..:..|:.||||||..|::.||..|:..:..:..|:.    :..:....::..:|.
Mouse    79 QHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRIGLS----VSEVISGYEIACKKA 139

  Fly   136 NEMAVQIV------EQSKDQQRALLEKCAATAMSSKLIHQQKDFFSRIVVDAVLSLDELLP---- 190
            :|:..::|      .:..|:..:||.    |::.||. :..:.|.::::..|.:|   :.|
Mouse   140 HEILPELVCCSAKNLRDVDEVSSLLR----TSIMSKQ-YGSETFLAKLIAQACVS---IFPDSGN 196

  Fly   191 --LNMIGIKKVTGGSLEESQLVSGVAFKKTFSYAGFEMAPKSYDNCKIALLNIELELKAERDNAE 253
              ::.|.:.|:.|..:..|.::.|:.|||.     .|....|..:.|||:.:...:.........
Mouse   197 FNVDNIRVCKILGSGIYSSSVLHGMVFKKE-----TEGDVTSVKDAKIAVYSCPFDGMITETKGT 256

  Fly   254 IRVDNVKEYQKVVDAEWQILYNKLAKIHESGANVVLSKLPIGDVATQYFADRDIFCAGRVPEEDL 318
            :.:...:|.......|..::..::..|..:||||:::...:.|:|..|....:|.......:.||
Mouse   257 VLIKTAEELMNFSKGEENLMDAQVKAIAGTGANVIVTGGKVADIALHYANKYNIMLVRLNSKWDL 321

  Fly   319 KRTMKACGGAVMTTANDIKPNVLGLCEHFEERQVGGERFNLFQ-GCPNAKTSTLILRGGAEQFLE 382
            :|..|..|...:..........:|.|:.....:||..:..:|: ...:...||::|||..:..::
Mouse   322 RRLCKTVGATALPKLTPPVQEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIVLRGSTDNLMD 386

  Fly   383 ETERSLHDAIMIVRRTIKHDSVVAGGGAIEMELSKLLRDYSRTIAGKEQLLIAAIAKGLEIIPRQ 447
            :.||::.|.:...:...:...:|.||||.|:||:|.:..|..|..|.||..|...|:..|.|||.
Mouse   387 DIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAEAFEAIPRA 451

  Fly   448 LCDNAGFDATNILNKLRQKHAQGGQWYGVDINKE--DISDNYEQCVWEPSIIKINALTAAAEAAC 510
            |.:|:|..|..:::||...|.:|.:..|:||..|  .:.|..|..:.:..:.|..|:..|..||.
Mouse   452 LAENSGVKANEVISKLYSVHQEGNKNVGLDIEAEVPAVKDMLEASILDTYLGKYWAIKLATNAAV 516

  Fly   511 MILSVDETIKSPKAGEP-PMAG 531
            .:|.||:.|.:..||.| |.:|
Mouse   517 TVLRVDQIIMAKPAGGPKPPSG 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT7	NP_649835.1	TCP1_eta	4..524	CDD:239456	140/532 (26%)
Cct8	NP_033970.3	chap_CCT_theta	10..539	CDD:274087	145/542 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	529..548		5/10 (50%)